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The map label for this gene is cysC

Identifier: 86606200

GI number: 86606200

Start: 1545458

End: 1545988

Strand: Reverse

Name: cysC

Synonym: CYA_1535

Alternate gene names: 86606200

Gene position: 1545988-1545458 (Counterclockwise)

Preceding gene: 86606202

Following gene: 86606199

Centisome position: 52.71

GC content: 61.39

Gene sequence:

>531_bases
ATGGGGCGGCGGGGGGTAACGGTCTGGTTTACGGGGCTCAGCGGCGCGGGCAAAACCACCCTGAGCTGCGGTGTCGCCCA
GCAGTTACAGGCTTTGGGGTTGCCGGTGGAAGTGCTCGATGGAGACCTGGTGCGGCAACACCTCAGCAAGGAACTGGGCT
TCAGCAGGGCGGATCGGGATGAGAACGTTCGTCGCATCGGCTTTGTGGCAGAGATGCTGACCCGCCACGGGGTGATCGTG
CTGGTGTCGGCCATCTCCCCCTATCGCGCCACCCGGCAGGAGGTGCGGCAGCAGATCGGCAACTTCATCGAAGTCTTTGT
GGACGCCCCCCTGGAAGTTTGTGAACAGCGCGATGTGAAAGGCCTCTACCGCAAAGCGCGGGCAGGCCTCATCCGGCACT
TCACCGGCATCGACGACCCCTACGAGCCGCCAGAATATCCAGAGGTGGTCTGCAAAACCGCCGAGCAAAGCATCTCTGAA
TGTATCGACTTGGTGATGCAAAGCCTGAGAAGCCACGGCTATCTCCAATAG

Upstream 100 bases:

>100_bases
GCGGCGGCATGGCAGAGGGAGAATGGACAATGTCTCGAGTGTATCACTCTGGGCGGGGGATGATATTCTGGCAAAGCCCA
AGGAGAAGGGATCTACACCC

Downstream 100 bases:

>100_bases
GGCGCTGGGCCTGGCGGGTTTGGGATCCTTGTGGGAAGATGTGAACAAGCATTTCGTTTCTGAGAATCAAGGTAGCTATG
GCAGTGACTCGTGCCGGACG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MGRRGVTVWFTGLSGAGKTTLSCGVAQQLQALGLPVEVLDGDLVRQHLSKELGFSRADRDENVRRIGFVAEMLTRHGVIV
LVSAISPYRATRQEVRQQIGNFIEVFVDAPLEVCEQRDVKGLYRKARAGLIRHFTGIDDPYEPPEYPEVVCKTAEQSISE
CIDLVMQSLRSHGYLQ

Sequences:

>Translated_176_residues
MGRRGVTVWFTGLSGAGKTTLSCGVAQQLQALGLPVEVLDGDLVRQHLSKELGFSRADRDENVRRIGFVAEMLTRHGVIV
LVSAISPYRATRQEVRQQIGNFIEVFVDAPLEVCEQRDVKGLYRKARAGLIRHFTGIDDPYEPPEYPEVVCKTAEQSISE
CIDLVMQSLRSHGYLQ
>Mature_175_residues
GRRGVTVWFTGLSGAGKTTLSCGVAQQLQALGLPVEVLDGDLVRQHLSKELGFSRADRDENVRRIGFVAEMLTRHGVIVL
VSAISPYRATRQEVRQQIGNFIEVFVDAPLEVCEQRDVKGLYRKARAGLIRHFTGIDDPYEPPEYPEVVCKTAEQSISEC
IDLVMQSLRSHGYLQ

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=173, Percent_Identity=54.3352601156069, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI34447231, Length=173, Percent_Identity=49.7109826589595, Blast_Score=172, Evalue=1e-43,
Organism=Homo sapiens, GI62912492, Length=173, Percent_Identity=49.7109826589595, Blast_Score=172, Evalue=2e-43,
Organism=Escherichia coli, GI1789107, Length=171, Percent_Identity=51.4619883040936, Blast_Score=177, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17542422, Length=178, Percent_Identity=48.876404494382, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6322852, Length=171, Percent_Identity=47.3684210526316, Blast_Score=165, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24667032, Length=176, Percent_Identity=46.0227272727273, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24667028, Length=176, Percent_Identity=46.0227272727273, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24667036, Length=176, Percent_Identity=46.0227272727273, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI116007838, Length=176, Percent_Identity=46.0227272727273, Blast_Score=159, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24667044, Length=176, Percent_Identity=46.0227272727273, Blast_Score=159, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24667040, Length=176, Percent_Identity=46.0227272727273, Blast_Score=159, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_SYNJA (Q2JUC0)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474963.1
- ProteinModelPortal:   Q2JUC0
- SMR:   Q2JUC0
- STRING:   Q2JUC0
- GeneID:   3897141
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_1535
- TIGR:   CYA_1535
- eggNOG:   COG0529
- HOGENOM:   HBG309946
- OMA:   ITITAFV
- ProtClustDB:   PRK00889
- BioCyc:   SSP321327:CYA_1535-MONOMER
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 19630; Mature: 19499

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: ACT_SITE 86-86

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRGVTVWFTGLSGAGKTTLSCGVAQQLQALGLPVEVLDGDLVRQHLSKELGFSRADRD
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCCC
ENVRRIGFVAEMLTRHGVIVLVSAISPYRATRQEVRQQIGNFIEVFVDAPLEVCEQRDVK
HHHHHHHHHHHHHHHCCHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHH
GLYRKARAGLIRHFTGIDDPYEPPEYPEVVCKTAEQSISECIDLVMQSLRSHGYLQ
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GRRGVTVWFTGLSGAGKTTLSCGVAQQLQALGLPVEVLDGDLVRQHLSKELGFSRADRD
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCCC
ENVRRIGFVAEMLTRHGVIVLVSAISPYRATRQEVRQQIGNFIEVFVDAPLEVCEQRDVK
HHHHHHHHHHHHHHHCCHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHH
GLYRKARAGLIRHFTGIDDPYEPPEYPEVVCKTAEQSISECIDLVMQSLRSHGYLQ
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA