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The map label for this gene is azr [H]

Identifier: 86606163

GI number: 86606163

Start: 1505050

End: 1505595

Strand: Reverse

Name: azr [H]

Synonym: CYA_1496

Alternate gene names: 86606163

Gene position: 1505595-1505050 (Counterclockwise)

Preceding gene: 86606164

Following gene: 86606162

Centisome position: 51.34

GC content: 58.24

Gene sequence:

>546_bases
GTGGCCATCGGCGGCAGCTTGCGGCCCAATTCTTTGACTTATCAGGCGCTAGAGGTGGTGCGGCGCGAGTTTGAGAGGTT
GAGGCTTCTCTTGCACATCCTCGACCTGCGGCAAATGAAGTTGCCCTTTGCCGATGGTTCGGAATCCTACCCGGACTATC
CCGACGTGGAGGTTTTGCGGGCAACAATGAAGCGGGCCGATGGGATCATCCTGGCTAGCCCTGAGTACCACGGCGGCATC
AGCGGCAGCCTGAAGAATGCTCTCGATCTCTTGAGCTTTGAACACTTAGAGGGCAAGGTCTTCGGGCTGATCAGCGTTTT
GGGCGGTGAGAGCAACAGCAATACCCTCAACCAGATGCGTTTAATTGTGCGGTGGGTGCATGGCTGGGCGATCCCGGAGC
AGATTGCCATTGGTCGGGCTTGGAGCGCCTTCGATGAGCAGGGCAACCTCAAGGACGAAAACCTACGCCAGCGCTTGCAA
CGCTTTGTGCAGAGCTTGGTCACCAACACCTCCAAACTGCGCGGGTCCCGGCTCCCAGCTCCTTGA

Upstream 100 bases:

>100_bases
TAATGTCTGCTCAGGAGCCTGGCTTATGTCTCCTTCAACCCTGCAAGCCCCTACTGTCGATTGGCAAGCCGTCATGGCTG
AAGCCTCTGGAGCTTGTTTC

Downstream 100 bases:

>100_bases
AAAGGGCCTAGGTTCCCCAGCAGCCCCATTTTCAAGAGGGGCTTCCCCTTTCCTGGGAGAGGGGCTGACGCCCAAGTAAC
GGCATGGCTAAGGTGGGCCA

Product: NADPH-dependent FMN reductase

Products: NAD(P)(+); FMNH(2). [C]

Alternate protein names: Azobenzene reductase [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAIGGSLRPNSLTYQALEVVRREFERLRLLLHILDLRQMKLPFADGSESYPDYPDVEVLRATMKRADGIILASPEYHGGI
SGSLKNALDLLSFEHLEGKVFGLISVLGGESNSNTLNQMRLIVRWVHGWAIPEQIAIGRAWSAFDEQGNLKDENLRQRLQ
RFVQSLVTNTSKLRGSRLPAP

Sequences:

>Translated_181_residues
MAIGGSLRPNSLTYQALEVVRREFERLRLLLHILDLRQMKLPFADGSESYPDYPDVEVLRATMKRADGIILASPEYHGGI
SGSLKNALDLLSFEHLEGKVFGLISVLGGESNSNTLNQMRLIVRWVHGWAIPEQIAIGRAWSAFDEQGNLKDENLRQRLQ
RFVQSLVTNTSKLRGSRLPAP
>Mature_180_residues
AIGGSLRPNSLTYQALEVVRREFERLRLLLHILDLRQMKLPFADGSESYPDYPDVEVLRATMKRADGIILASPEYHGGIS
GSLKNALDLLSFEHLEGKVFGLISVLGGESNSNTLNQMRLIVRWVHGWAIPEQIAIGRAWSAFDEQGNLKDENLRQRLQR
FVQSLVTNTSKLRGSRLPAP

Specific function: Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an electron donor for its activity [H]

COG id: COG0431

COG function: function code R; Predicted flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the azoreductase type 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: 1.5.1.29 [C]

Molecular weight: Translated: 20338; Mature: 20206

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGGSLRPNSLTYQALEVVRREFERLRLLLHILDLRQMKLPFADGSESYPDYPDVEVLR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
ATMKRADGIILASPEYHGGISGSLKNALDLLSFEHLEGKVFGLISVLGGESNSNTLNQMR
HHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHH
LIVRWVHGWAIPEQIAIGRAWSAFDEQGNLKDENLRQRLQRFVQSLVTNTSKLRGSRLPA
HHHHHHHHCCCHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
P
C
>Mature Secondary Structure 
AIGGSLRPNSLTYQALEVVRREFERLRLLLHILDLRQMKLPFADGSESYPDYPDVEVLR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
ATMKRADGIILASPEYHGGISGSLKNALDLLSFEHLEGKVFGLISVLGGESNSNTLNQMR
HHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHH
LIVRWVHGWAIPEQIAIGRAWSAFDEQGNLKDENLRQRLQRFVQSLVTNTSKLRGSRLPA
HHHHHHHHCCCHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H; FMN [C]

Specific reaction: NAD(P)H + FMN = NAD(P)(+) + FMNH(2). [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]