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The map label for this gene is sppA-2

Identifier: 86606131

GI number: 86606131

Start: 1468878

End: 1469918

Strand: Reverse

Name: sppA-2

Synonym: CYA_1463

Alternate gene names: 86606131

Gene position: 1469918-1468878 (Counterclockwise)

Preceding gene: 86606135

Following gene: 86606130

Centisome position: 50.12

GC content: 62.82

Gene sequence:

>1041_bases
GTGACACAGGGATCTCAGCTTAACCGCCTTTTGGCCGCTTCCTTGCTGGTGGTCTGCCTGATTGCGGCTGTTATTGGCGG
CACACGACCTGCCGCAGAGTCGGTTCGGGGTGGCGTCGGGCTAGAGGCCCCTCGAGGGGCGAATCGCATTGAGGTGGTTA
CCATCGAGGGAACGATAGGAGGGCCACGGGGCTCGACTTTGGTAGGTTTGCCCACCTCTCCCTTAGATCAGTTGCGGGAA
GCTGTCGAGGATCGCGCCGTCAAGGCTGTATTGCTGCGCATCAACAGCCCGGGCGGGGCTGTGGGATCCAGCCAGGAGCT
CTACCGCGCCGTCACGGCTCTGCGGGAAGCCGGCAAGCCGGTGATTGCCGTCATGGAAGACGTTGCCGCCAGCGGCGGCT
ACTATGTAGCCAGTGCTGCCGACAAGATCTACGCCAACCCGGGCACCCTGACCGGCAGCATAGGGGTGATCATCAGCGGC
CTCAACTTTGGCAAACTGCTCGACAACTACGGCATAGAGCCGCAGACCTTCAAAACCGGCGAGTACAAAGACATTCTTTC
CCCTTTCCGGGCTGCCACCCCCCAAGAGCAACGTCTGCTGCAAGAGTTGGTGGAGGATACCCTCGACCAGTTCGTTCGCG
ATGTGGCCCGCGGACGCCAGCGCTTGCCGGACAAAGGGGCAGAAAAGGTGCTGGATGCGGAGATGATCGCCCGACGGCAA
AGCTTGGATGAGGCGCGGGTGCGCCAGTTGGCCGATGGGCGCATCTTCACCGGGGCGCAGGCTGTGGAGTTGGGCCTGGT
AGATGCCCTGGGAGGATATGCCGAAGCCGTGGAAGATCTGCGGCGCATGACCGGGGATCCCTCTTTGTCGCCAGCAACGG
CGAGAGATCCCTTCCAACGCGCCCTGCAGCGACTATTGAGCCAAGGACTGCCTCCGCAAGGGCAAAATCTCTGGCCCGCT
CGACTGTTGGGGAGCCACGAGGTGGCCGGGATCCCGGAAGTGCCGCTGCTGTGGATGGCGCCCGGGTGGACTTTGCGCTA
A

Upstream 100 bases:

>100_bases
CGTCCACTTGCAAAAGTGGAGATTGGATCCACCTGGCTCCTGCCCTCTGTTGCAGGAGCTTGCCGGGTGATAGAACGGAG
TCAGCGACATTGGGGGGCTT

Downstream 100 bases:

>100_bases
ACCTGACAGTGATCATAGGCTTGGTGTGAGGGGTGAAGCTGTGGATCACACGCCGGACGACGCTTCTGCGCTGGCGACGG
CAGGGCATAGCCCCCTGGCC

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTQGSQLNRLLAASLLVVCLIAAVIGGTRPAAESVRGGVGLEAPRGANRIEVVTIEGTIGGPRGSTLVGLPTSPLDQLRE
AVEDRAVKAVLLRINSPGGAVGSSQELYRAVTALREAGKPVIAVMEDVAASGGYYVASAADKIYANPGTLTGSIGVIISG
LNFGKLLDNYGIEPQTFKTGEYKDILSPFRAATPQEQRLLQELVEDTLDQFVRDVARGRQRLPDKGAEKVLDAEMIARRQ
SLDEARVRQLADGRIFTGAQAVELGLVDALGGYAEAVEDLRRMTGDPSLSPATARDPFQRALQRLLSQGLPPQGQNLWPA
RLLGSHEVAGIPEVPLLWMAPGWTLR

Sequences:

>Translated_346_residues
MTQGSQLNRLLAASLLVVCLIAAVIGGTRPAAESVRGGVGLEAPRGANRIEVVTIEGTIGGPRGSTLVGLPTSPLDQLRE
AVEDRAVKAVLLRINSPGGAVGSSQELYRAVTALREAGKPVIAVMEDVAASGGYYVASAADKIYANPGTLTGSIGVIISG
LNFGKLLDNYGIEPQTFKTGEYKDILSPFRAATPQEQRLLQELVEDTLDQFVRDVARGRQRLPDKGAEKVLDAEMIARRQ
SLDEARVRQLADGRIFTGAQAVELGLVDALGGYAEAVEDLRRMTGDPSLSPATARDPFQRALQRLLSQGLPPQGQNLWPA
RLLGSHEVAGIPEVPLLWMAPGWTLR
>Mature_345_residues
TQGSQLNRLLAASLLVVCLIAAVIGGTRPAAESVRGGVGLEAPRGANRIEVVTIEGTIGGPRGSTLVGLPTSPLDQLREA
VEDRAVKAVLLRINSPGGAVGSSQELYRAVTALREAGKPVIAVMEDVAASGGYYVASAADKIYANPGTLTGSIGVIISGL
NFGKLLDNYGIEPQTFKTGEYKDILSPFRAATPQEQRLLQELVEDTLDQFVRDVARGRQRLPDKGAEKVLDAEMIARRQS
LDEARVRQLADGRIFTGAQAVELGLVDALGGYAEAVEDLRRMTGDPSLSPATARDPFQRALQRLLSQGLPPQGQNLWPAR
LLGSHEVAGIPEVPLLWMAPGWTLR

Specific function: Digestion of the cleaved signal peptides [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=201, Percent_Identity=35.8208955223881, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787527, Length=189, Percent_Identity=32.8042328042328, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 36816; Mature: 36684

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQGSQLNRLLAASLLVVCLIAAVIGGTRPAAESVRGGVGLEAPRGANRIEVVTIEGTIG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEECCCC
GPRGSTLVGLPTSPLDQLREAVEDRAVKAVLLRINSPGGAVGSSQELYRAVTALREAGKP
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCCC
VIAVMEDVAASGGYYVASAADKIYANPGTLTGSIGVIISGLNFGKLLDNYGIEPQTFKTG
HHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCCHHHHEECCCHHHHHHHCCCCCCCCCCC
EYKDILSPFRAATPQEQRLLQELVEDTLDQFVRDVARGRQRLPDKGAEKVLDAEMIARRQ
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SLDEARVRQLADGRIFTGAQAVELGLVDALGGYAEAVEDLRRMTGDPSLSPATARDPFQR
HHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
ALQRLLSQGLPPQGQNLWPARLLGSHEVAGIPEVPLLWMAPGWTLR
HHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TQGSQLNRLLAASLLVVCLIAAVIGGTRPAAESVRGGVGLEAPRGANRIEVVTIEGTIG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEEEEEECCCC
GPRGSTLVGLPTSPLDQLREAVEDRAVKAVLLRINSPGGAVGSSQELYRAVTALREAGKP
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCCC
VIAVMEDVAASGGYYVASAADKIYANPGTLTGSIGVIISGLNFGKLLDNYGIEPQTFKTG
HHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCCHHHHEECCCHHHHHHHCCCCCCCCCCC
EYKDILSPFRAATPQEQRLLQELVEDTLDQFVRDVARGRQRLPDKGAEKVLDAEMIARRQ
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SLDEARVRQLADGRIFTGAQAVELGLVDALGGYAEAVEDLRRMTGDPSLSPATARDPFQR
HHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
ALQRLLSQGLPPQGQNLWPARLLGSHEVAGIPEVPLLWMAPGWTLR
HHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]