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The map label for this gene is fur [H]

Identifier: 86606053

GI number: 86606053

Start: 1390490

End: 1390939

Strand: Reverse

Name: fur [H]

Synonym: CYA_1383

Alternate gene names: 86606053

Gene position: 1390939-1390490 (Counterclockwise)

Preceding gene: 86606054

Following gene: 86606052

Centisome position: 47.43

GC content: 59.11

Gene sequence:

>450_bases
ATGTCCTCCTCCCGCCAGACCCGCAGCCAAAAACTGATCCTGGAAGTCTTGAAGCAGAGCTTGCGGCCCCTCTCGGCCCA
AGAGATCTTCCTGGAGTTGCGCAATGCCAACCATAGCGTTGGCTTGGCCACGGTCTACCGGGCTTTGGAGGCTCTGCGCA
ACGAGGGCAAGCTGCAAGCGGTCAACTTGGGAGATCAGCAGACCTACTATCAGGTTTTGCCCAGCAACGGCCACAACCGC
CATCACCTCATTTGCACCGAATGTCGGCGGGTGGTGCCTCTGCCGGATTGCCCAGTGGGAGACCTGGAGGAGCAGCTTGC
CAGCCGCTACCAATTTGTCATCGAGTACCATGTGCTTGACTTCTACGGCATCTGCGCCGAATGCCGTGGGGAGAGCAGCT
CCAACCCTGGCTCACAGCGATCCTCTTGCCTTGAGGCCAAACCGCAATGA

Upstream 100 bases:

>100_bases
CAAATGTTCGACCAAATGCACCAAACCCTAGAGCGCATGAAAGCCGAGGCCGACGCCGAGCGCTAACCTTGCTGGTGACC
CCTCAGAACGAAAAGGGATC

Downstream 100 bases:

>100_bases
TGAACTATCTCTGGACGCTGTTGATCGGATTGGCGGGCGCCCTGATTGCAGTCAAGCTGAGGCTGCCGGCAGGAGCTTTG
GTGGGTTCGATGGTAGCAGT

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSSSRQTRSQKLILEVLKQSLRPLSAQEIFLELRNANHSVGLATVYRALEALRNEGKLQAVNLGDQQTYYQVLPSNGHNR
HHLICTECRRVVPLPDCPVGDLEEQLASRYQFVIEYHVLDFYGICAECRGESSSNPGSQRSSCLEAKPQ

Sequences:

>Translated_149_residues
MSSSRQTRSQKLILEVLKQSLRPLSAQEIFLELRNANHSVGLATVYRALEALRNEGKLQAVNLGDQQTYYQVLPSNGHNR
HHLICTECRRVVPLPDCPVGDLEEQLASRYQFVIEYHVLDFYGICAECRGESSSNPGSQRSSCLEAKPQ
>Mature_148_residues
SSSRQTRSQKLILEVLKQSLRPLSAQEIFLELRNANHSVGLATVYRALEALRNEGKLQAVNLGDQQTYYQVLPSNGHNRH
HLICTECRRVVPLPDCPVGDLEEQLASRYQFVIEYHVLDFYGICAECRGESSSNPGSQRSSCLEAKPQ

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=129, Percent_Identity=28.6821705426357, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16801; Mature: 16670

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSRQTRSQKLILEVLKQSLRPLSAQEIFLELRNANHSVGLATVYRALEALRNEGKLQA
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEE
VNLGDQQTYYQVLPSNGHNRHHLICTECRRVVPLPDCPVGDLEEQLASRYQFVIEYHVLD
ECCCCCCCEEEECCCCCCCCCCEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FYGICAECRGESSSNPGSQRSSCLEAKPQ
HHHHHHHHCCCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
SSSRQTRSQKLILEVLKQSLRPLSAQEIFLELRNANHSVGLATVYRALEALRNEGKLQA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEE
VNLGDQQTYYQVLPSNGHNRHHLICTECRRVVPLPDCPVGDLEEQLASRYQFVIEYHVLD
ECCCCCCCEEEECCCCCCCCCCEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FYGICAECRGESSSNPGSQRSSCLEAKPQ
HHHHHHHHCCCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]