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The map label for this gene is holB

Identifier: 86605952

GI number: 86605952

Start: 1285137

End: 1286150

Strand: Reverse

Name: holB

Synonym: CYA_1270

Alternate gene names: 86605952

Gene position: 1286150-1285137 (Counterclockwise)

Preceding gene: 86605953

Following gene: 86605951

Centisome position: 43.85

GC content: 64.89

Gene sequence:

>1014_bases
ATGGTTGAGGGAGTCACGGTTCTGCCCCCCCAGCACATCGTCGGGCAGGAGCTGGCGGCGCGGCTGCTCGTGGCGGCCTT
GGAAAAGGGGCGGGTGACCTCAAGCTACTGTTTCTTGGGACCAGAAGGGGTGGGACGGAGCCTGATGGCCCGCTGGTTTG
CCCAGGCCCTCTTCTGCGAGGCCAGCTCAGGGATCCCTTGCGGCCAGTGCTCCAACTGCCGTTGGCTCCTCGCAGGCACC
CATCCCGATCTCCACTGGGTCAGCCCCACCTATGTCCACCAGGGCCGCCTGATAGCAGCAGACGCCCCGGAGGCACAAGC
TCTGCAGCGGCGCTCCCCGCCGCAAATTCGCCTGGAACAGGTGCAGGAAGTGGTTCGCTTCTGTGCCCGTAGGCCAATGC
ACGCCCGCCGCTCGCTAGTTGTACTGGAGGGAGCGGAAACCCTGACAGAAAGTGCGGCCAATGCCCTGCTGAAAACCCTG
GAGGAGCCTGAGCCGGCCCACATCGTTCTTATCGCCTCCCACCACTCGCCTACCCCCCCTCCCCACCCTTTGCCACCGAC
GCTGCTGTCCCGCTGCCAGATGGTGCCGTTTCGCCGCCTCAGCTCGGCAGAGATGGAGCAAGTGTTGACAGCTTTGGGCT
GCCCGGAGCTGCCCGGGATCCCTCGCTCTGAGCTAATTGCCCTAGCCCAAGGCAGCCCTGGACGGGCGCTGGCCGCCCAG
CAGCACCTGCAAAGCCTTCCGCCGTCACTGCTGCAGGACCTAAGACGCTGGCCCCACTCGCTGCGGCAGGCGCTGGAAGT
GGCTAGGGCAGTGGCTGCTCTCGATTTGCCGGCGCAGCTGTGGCTGATTGACTATCTGCAGCAGCAGTTCTGGGCGCAGG
GATCCCGCCAGGCCATCCGGCAACTGGAGCAGATTCGCCAACAGCTTTTGCAATTTGTGCAGCCGCGCCTTGCTTGGGAG
GTCAACCTGGCCGGATTCGACAGCAGTGGCAACCCAAGCCCTGTGGCAAAGTGA

Upstream 100 bases:

>100_bases
GAGGGATCCCTTGGTGGAGGAGGGGCTGTGGCAATTTCTCTTGCCGACCTTTGCCTGCGACTAGGCAACTTTGCCGATGC
TTCAGCCCAGAGCTGCCGAG

Downstream 100 bases:

>100_bases
GGAGAGAGCGTTCAAGACGTGTCTATGCCTGCATGGCTTTCCGCCCTCCTTGCCGCCCTTGGAGGCTACCTGCTGGGATC
CATCCCCACCGGCTACTGGG

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MVEGVTVLPPQHIVGQELAARLLVAALEKGRVTSSYCFLGPEGVGRSLMARWFAQALFCEASSGIPCGQCSNCRWLLAGT
HPDLHWVSPTYVHQGRLIAADAPEAQALQRRSPPQIRLEQVQEVVRFCARRPMHARRSLVVLEGAETLTESAANALLKTL
EEPEPAHIVLIASHHSPTPPPHPLPPTLLSRCQMVPFRRLSSAEMEQVLTALGCPELPGIPRSELIALAQGSPGRALAAQ
QHLQSLPPSLLQDLRRWPHSLRQALEVARAVAALDLPAQLWLIDYLQQQFWAQGSRQAIRQLEQIRQQLLQFVQPRLAWE
VNLAGFDSSGNPSPVAK

Sequences:

>Translated_337_residues
MVEGVTVLPPQHIVGQELAARLLVAALEKGRVTSSYCFLGPEGVGRSLMARWFAQALFCEASSGIPCGQCSNCRWLLAGT
HPDLHWVSPTYVHQGRLIAADAPEAQALQRRSPPQIRLEQVQEVVRFCARRPMHARRSLVVLEGAETLTESAANALLKTL
EEPEPAHIVLIASHHSPTPPPHPLPPTLLSRCQMVPFRRLSSAEMEQVLTALGCPELPGIPRSELIALAQGSPGRALAAQ
QHLQSLPPSLLQDLRRWPHSLRQALEVARAVAALDLPAQLWLIDYLQQQFWAQGSRQAIRQLEQIRQQLLQFVQPRLAWE
VNLAGFDSSGNPSPVAK
>Mature_337_residues
MVEGVTVLPPQHIVGQELAARLLVAALEKGRVTSSYCFLGPEGVGRSLMARWFAQALFCEASSGIPCGQCSNCRWLLAGT
HPDLHWVSPTYVHQGRLIAADAPEAQALQRRSPPQIRLEQVQEVVRFCARRPMHARRSLVVLEGAETLTESAANALLKTL
EEPEPAHIVLIASHHSPTPPPHPLPPTLLSRCQMVPFRRLSSAEMEQVLTALGCPELPGIPRSELIALAQGSPGRALAAQ
QHLQSLPPSLLQDLRRWPHSLRQALEVARAVAALDLPAQLWLIDYLQQQFWAQGSRQAIRQLEQIRQQLLQFVQPRLAWE
VNLAGFDSSGNPSPVAK

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=197, Percent_Identity=31.4720812182741, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37121; Mature: 37121

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEGVTVLPPQHIVGQELAARLLVAALEKGRVTSSYCFLGPEGVGRSLMARWFAQALFCE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHCCHHHHHHHHHHHHHHH
ASSGIPCGQCSNCRWLLAGTHPDLHWVSPTYVHQGRLIAADAPEAQALQRRSPPQIRLEQ
CCCCCCCCCCCCCEEEEECCCCCCEECCCCEEECCEEEECCCCHHHHHHHCCCCCHHHHH
VQEVVRFCARRPMHARRSLVVLEGAETLTESAANALLKTLEEPEPAHIVLIASHHSPTPP
HHHHHHHHHCCCHHHHCCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
PHPLPPTLLSRCQMVPFRRLSSAEMEQVLTALGCPELPGIPRSELIALAQGSPGRALAAQ
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEECCCCCCHHHHH
QHLQSLPPSLLQDLRRWPHSLRQALEVARAVAALDLPAQLWLIDYLQQQFWAQGSRQAIR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHH
QLEQIRQQLLQFVQPRLAWEVNLAGFDSSGNPSPVAK
HHHHHHHHHHHHHCHHHEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MVEGVTVLPPQHIVGQELAARLLVAALEKGRVTSSYCFLGPEGVGRSLMARWFAQALFCE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHCCHHHHHHHHHHHHHHH
ASSGIPCGQCSNCRWLLAGTHPDLHWVSPTYVHQGRLIAADAPEAQALQRRSPPQIRLEQ
CCCCCCCCCCCCCEEEEECCCCCCEECCCCEEECCEEEECCCCHHHHHHHCCCCCHHHHH
VQEVVRFCARRPMHARRSLVVLEGAETLTESAANALLKTLEEPEPAHIVLIASHHSPTPP
HHHHHHHHHCCCHHHHCCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
PHPLPPTLLSRCQMVPFRRLSSAEMEQVLTALGCPELPGIPRSELIALAQGSPGRALAAQ
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEECCCCCCHHHHH
QHLQSLPPSLLQDLRRWPHSLRQALEVARAVAALDLPAQLWLIDYLQQQFWAQGSRQAIR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHH
QLEQIRQQLLQFVQPRLAWEVNLAGFDSSGNPSPVAK
HHHHHHHHHHHHHCHHHEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]