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The map label for this gene is arsA [H]

Identifier: 86605793

GI number: 86605793

Start: 1129063

End: 1131117

Strand: Reverse

Name: arsA [H]

Synonym: CYA_1104

Alternate gene names: 86605793

Gene position: 1131117-1129063 (Counterclockwise)

Preceding gene: 86605794

Following gene: 86605792

Centisome position: 38.57

GC content: 65.5

Gene sequence:

>2055_bases
GTGCCAGAAGGGATCCCTTTGCAGCCTGCTCAACTCGATTGTGGCGGGAGCGCTTTCCGCCTGTCTCTCCTTTCTCCTTG
CCAGCGTCTGCTGCTGTTTAGCGGCAAGGGGGGCGTAGGCAAAACCACCCTCACCTGTGCCCTGGCCCGTCACCTGGCCC
AGGCGCAACCAGAGCGCCGTCTGCTGCTCCTGTCCACCGATCCGGCCCACTCCCTGGGGGATGTGCTGGGGATCCCGGTG
GCCGACGTTCCCCAGCCCCTGCCGGATTGGCCCAACTTGCAGGTGCGGGCTCTCCAGGCCGAGGTGTTGCTGCAGGATTT
CAAGCAGACCTACGGCCCGGCTCTGGAGCTGATTGCCGAGCGGGGCAGTTGGCTGGCCAAGGAAGATCTCCTGCCCCTTT
GGGATCTGGACTGGCCGGGGGTGGACGAGCTGATGGCCATCTTAGAGGTCAACCGGCTGCTGGCGGGCCAAGAGGTGGAT
ACAGTTATCCTGGATACCGCCCCCACCGGCCACACCCTGCGGCTGTTGGAACTGCCCGACTTTCTCGACAATTTGCTGGC
GGTGTTTGCCACCTTCCAGGCCAAGCACCGCGAGGTTGTCCAATCCCTCACGGGCGCCTATCGACCGGATGAGGCCGACG
CCTTCCTGGCCCGCTTGCAGAGCGAGCTGGAGGGGGGCAAAGCCCGCCTCACCGACCCGGAGAGCACTGCCGCCTGGCTG
GTGCTGATCCCGGAGCCGTTGAGCGTGGCGGAGACGCGCCGCTTTTGTCAACAACTGCAAAGCCGCCGGGTGCCCATTGG
CGGCCTGTTGGTCAACCAGGTGTTGTTGGGAGCCAGCGGGAGAGCGTCGTCTGGGATCCCGCCGTCCCCCCTCTACCTGG
CCCGCCAGCAGGAACAGCGGCGCTGGCTAAAAGCGCTCCAAGAGGAGCTGCCTGGCTATCCCATCTGGGTTTGTCCCTAT
CAACTGGAGGAGCCCATTGGGCCGGCGGCCCTGGACAAGCTGGTGCAGCAGCTTCGTCCCTTGCCAGAGGTGCTGCTGCA
GTTGGAAGAGATTCCCGCTAGCCCAGGGGAGCCTGTCGGCGGGATCCCCTCCCCCCCAAGGGTGGCCCTGCCAGATTTTT
TGGCCCAAGGGATCCGCCTGCTGCTGGTGGGAGGCAAAGGCGGGGTAGGCAAGACCACGGTGGCCGGGGCGCTGGCCTGG
AACTTGGCCCAACGCCATCCCGACCGGCAGCTCTTGCTGGTCTCCATCGACCCGGCCCACTCGCTGGGGGATCTGTTCGG
GGTGAAATTGGGGCAAGATCCGCTGCCGCTGCTGCCCAATTTGCTGGGGCAGGAGATCGAGGCGGCGGCAGTGCTGGAGC
GCTTCCGGCAGGAGTACCTGGAAGAGGTGGCGGCCATCTTGGCCGGCGAAGGGACGGCGGGGGTGGAGGTTCAGTACGAC
CCCCAGGCCTGGCGGCAGCTTTTGCAGATGGCTCCACCGGGCCTGGACGAGGTGATGGCCCTGCTGACGGTGCTGGAGCA
GGAGGCCAGCGGCCAGTTCAACCTGGTGGTGGTGGATACAGCCCCCACCGGCCATCTCCTGCGCTTTTTGCAGATGCCGC
AGGCCCTGGAAGGCTGGGTAAGCCTGGCCCTCAAGCTGTGGCTAAAGTACCGCGACGTGGTGGGCCGGCCAGAATGGGCG
CAGCGGCTGCGGGATCTCTTGGCCCAGGTGCGGCAGCTCCGGCAGCGGCTGCGGGATCCCCAGTTTGCTAGCTTTATCCC
CGTCTTCAACCCCGAACAGGCAGTTCTGGCGGAAACTGAGCGCCTTCTGGCAGAACTGGATGCCCTGGGGATCCCTCATC
CCTATGCCGTTCTCAACCGCGTGTGGCCGGAGGATTCCACCCCCTTTGGTGCAGCTCTTCGGCGCCGCCACCAGGCCATC
CTGGCCCAGTTGCCCCAGCGCTTTCCCCAGCAGGCCATTGTCACCGTCCCTTTTCTGCACCCACCCAGCTTAGAGGCCAT
CGGGGCTTACCTGCTGGCTTCCTCTAGCCCGATGTTGCCAGAAACCTCCACCTAG

Upstream 100 bases:

>100_bases
GCTGGCGTGGGACAGAGGACGCCGGTTGTGGTGGGAGAGGGGAAACTTCGCTGATCTGGAGCATCCCTAAGGGAGATCCA
GGCCACAATGGGGGTGACCT

Downstream 100 bases:

>100_bases
CGCCTGGCAGAGCCGCTAGCCTGGAAAAGGTGCCAGTGCGGCTTTTCCCCCTCACCTTGCTGCTTTTGCCTATGGTGTTC
AACCTCCCCCTGCAAGCCAT

Product: arsenite-antimonite ArsAB efflux family transporter ATP-binding protein ArsAB

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MPEGIPLQPAQLDCGGSAFRLSLLSPCQRLLLFSGKGGVGKTTLTCALARHLAQAQPERRLLLLSTDPAHSLGDVLGIPV
ADVPQPLPDWPNLQVRALQAEVLLQDFKQTYGPALELIAERGSWLAKEDLLPLWDLDWPGVDELMAILEVNRLLAGQEVD
TVILDTAPTGHTLRLLELPDFLDNLLAVFATFQAKHREVVQSLTGAYRPDEADAFLARLQSELEGGKARLTDPESTAAWL
VLIPEPLSVAETRRFCQQLQSRRVPIGGLLVNQVLLGASGRASSGIPPSPLYLARQQEQRRWLKALQEELPGYPIWVCPY
QLEEPIGPAALDKLVQQLRPLPEVLLQLEEIPASPGEPVGGIPSPPRVALPDFLAQGIRLLLVGGKGGVGKTTVAGALAW
NLAQRHPDRQLLLVSIDPAHSLGDLFGVKLGQDPLPLLPNLLGQEIEAAAVLERFRQEYLEEVAAILAGEGTAGVEVQYD
PQAWRQLLQMAPPGLDEVMALLTVLEQEASGQFNLVVVDTAPTGHLLRFLQMPQALEGWVSLALKLWLKYRDVVGRPEWA
QRLRDLLAQVRQLRQRLRDPQFASFIPVFNPEQAVLAETERLLAELDALGIPHPYAVLNRVWPEDSTPFGAALRRRHQAI
LAQLPQRFPQQAIVTVPFLHPPSLEAIGAYLLASSSPMLPETST

Sequences:

>Translated_684_residues
MPEGIPLQPAQLDCGGSAFRLSLLSPCQRLLLFSGKGGVGKTTLTCALARHLAQAQPERRLLLLSTDPAHSLGDVLGIPV
ADVPQPLPDWPNLQVRALQAEVLLQDFKQTYGPALELIAERGSWLAKEDLLPLWDLDWPGVDELMAILEVNRLLAGQEVD
TVILDTAPTGHTLRLLELPDFLDNLLAVFATFQAKHREVVQSLTGAYRPDEADAFLARLQSELEGGKARLTDPESTAAWL
VLIPEPLSVAETRRFCQQLQSRRVPIGGLLVNQVLLGASGRASSGIPPSPLYLARQQEQRRWLKALQEELPGYPIWVCPY
QLEEPIGPAALDKLVQQLRPLPEVLLQLEEIPASPGEPVGGIPSPPRVALPDFLAQGIRLLLVGGKGGVGKTTVAGALAW
NLAQRHPDRQLLLVSIDPAHSLGDLFGVKLGQDPLPLLPNLLGQEIEAAAVLERFRQEYLEEVAAILAGEGTAGVEVQYD
PQAWRQLLQMAPPGLDEVMALLTVLEQEASGQFNLVVVDTAPTGHLLRFLQMPQALEGWVSLALKLWLKYRDVVGRPEWA
QRLRDLLAQVRQLRQRLRDPQFASFIPVFNPEQAVLAETERLLAELDALGIPHPYAVLNRVWPEDSTPFGAALRRRHQAI
LAQLPQRFPQQAIVTVPFLHPPSLEAIGAYLLASSSPMLPETST
>Mature_683_residues
PEGIPLQPAQLDCGGSAFRLSLLSPCQRLLLFSGKGGVGKTTLTCALARHLAQAQPERRLLLLSTDPAHSLGDVLGIPVA
DVPQPLPDWPNLQVRALQAEVLLQDFKQTYGPALELIAERGSWLAKEDLLPLWDLDWPGVDELMAILEVNRLLAGQEVDT
VILDTAPTGHTLRLLELPDFLDNLLAVFATFQAKHREVVQSLTGAYRPDEADAFLARLQSELEGGKARLTDPESTAAWLV
LIPEPLSVAETRRFCQQLQSRRVPIGGLLVNQVLLGASGRASSGIPPSPLYLARQQEQRRWLKALQEELPGYPIWVCPYQ
LEEPIGPAALDKLVQQLRPLPEVLLQLEEIPASPGEPVGGIPSPPRVALPDFLAQGIRLLLVGGKGGVGKTTVAGALAWN
LAQRHPDRQLLLVSIDPAHSLGDLFGVKLGQDPLPLLPNLLGQEIEAAAVLERFRQEYLEEVAAILAGEGTAGVEVQYDP
QAWRQLLQMAPPGLDEVMALLTVLEQEASGQFNLVVVDTAPTGHLLRFLQMPQALEGWVSLALKLWLKYRDVVGRPEWAQ
RLRDLLAQVRQLRQRLRDPQFASFIPVFNPEQAVLAETERLLAELDALGIPHPYAVLNRVWPEDSTPFGAALRRRHQAIL
AQLPQRFPQQAIVTVPFLHPPSLEAIGAYLLASSSPMLPETST

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=287, Percent_Identity=25.4355400696864, Blast_Score=101, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17557003, Length=306, Percent_Identity=27.1241830065359, Blast_Score=108, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320103, Length=326, Percent_Identity=30.3680981595092, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24586297, Length=308, Percent_Identity=26.6233766233766, Blast_Score=105, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016300
- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 75004; Mature: 74873

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEGIPLQPAQLDCGGSAFRLSLLSPCQRLLLFSGKGGVGKTTLTCALARHLAQAQPERR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCE
LLLLSTDPAHSLGDVLGIPVADVPQPLPDWPNLQVRALQAEVLLQDFKQTYGPALELIAE
EEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
RGSWLAKEDLLPLWDLDWPGVDELMAILEVNRLLAGQEVDTVILDTAPTGHTLRLLELPD
CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECHH
FLDNLLAVFATFQAKHREVVQSLTGAYRPDEADAFLARLQSELEGGKARLTDPESTAAWL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCEEE
VLIPEPLSVAETRRFCQQLQSRRVPIGGLLVNQVLLGASGRASSGIPPSPLYLARQQEQR
EEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
RWLKALQEELPGYPIWVCPYQLEEPIGPAALDKLVQQLRPLPEVLLQLEEIPASPGEPVG
HHHHHHHHHCCCCCEEECCHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
GIPSPPRVALPDFLAQGIRLLLVGGKGGVGKTTVAGALAWNLAQRHPDRQLLLVSIDPAH
CCCCCCCCCCHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCH
SLGDLFGVKLGQDPLPLLPNLLGQEIEAAAVLERFRQEYLEEVAAILAGEGTAGVEVQYD
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
PQAWRQLLQMAPPGLDEVMALLTVLEQEASGQFNLVVVDTAPTGHLLRFLQMPQALEGWV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCHHHHHHHH
SLALKLWLKYRDVVGRPEWAQRLRDLLAQVRQLRQRLRDPQFASFIPVFNPEQAVLAETE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHH
RLLAELDALGIPHPYAVLNRVWPEDSTPFGAALRRRHQAILAQLPQRFPQQAIVTVPFLH
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
PPSLEAIGAYLLASSSPMLPETST
CCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PEGIPLQPAQLDCGGSAFRLSLLSPCQRLLLFSGKGGVGKTTLTCALARHLAQAQPERR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCE
LLLLSTDPAHSLGDVLGIPVADVPQPLPDWPNLQVRALQAEVLLQDFKQTYGPALELIAE
EEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
RGSWLAKEDLLPLWDLDWPGVDELMAILEVNRLLAGQEVDTVILDTAPTGHTLRLLELPD
CCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECHH
FLDNLLAVFATFQAKHREVVQSLTGAYRPDEADAFLARLQSELEGGKARLTDPESTAAWL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCCEEE
VLIPEPLSVAETRRFCQQLQSRRVPIGGLLVNQVLLGASGRASSGIPPSPLYLARQQEQR
EEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
RWLKALQEELPGYPIWVCPYQLEEPIGPAALDKLVQQLRPLPEVLLQLEEIPASPGEPVG
HHHHHHHHHCCCCCEEECCHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
GIPSPPRVALPDFLAQGIRLLLVGGKGGVGKTTVAGALAWNLAQRHPDRQLLLVSIDPAH
CCCCCCCCCCHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCH
SLGDLFGVKLGQDPLPLLPNLLGQEIEAAAVLERFRQEYLEEVAAILAGEGTAGVEVQYD
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEC
PQAWRQLLQMAPPGLDEVMALLTVLEQEASGQFNLVVVDTAPTGHLLRFLQMPQALEGWV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCHHHHHHHH
SLALKLWLKYRDVVGRPEWAQRLRDLLAQVRQLRQRLRDPQFASFIPVFNPEQAVLAETE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHH
RLLAELDALGIPHPYAVLNRVWPEDSTPFGAALRRRHQAILAQLPQRFPQQAIVTVPFLH
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
PPSLEAIGAYLLASSSPMLPETST
CCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9847077; 11016950 [H]