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The map label for this gene is ribH

Identifier: 86605774

GI number: 86605774

Start: 1098940

End: 1099530

Strand: Reverse

Name: ribH

Synonym: CYA_1078

Alternate gene names: 86605774

Gene position: 1099530-1098940 (Counterclockwise)

Preceding gene: 86605776

Following gene: 86605771

Centisome position: 37.49

GC content: 61.25

Gene sequence:

>591_bases
ATGGCAGTTTACGAAGGCAATTTTGTTCAGACGGGGGATCTGCGTCTGGCCATTGTTATCAGTCGGTTTAACGATTTGAT
TGCCGGCAAATTGTTGGAGGGGTGCCAAGATGCCCTGAAGCGGCATGGCATCGATGTCAGCTCGGAGAGCCAGCAGGTGG
ACTATTACTGGGTGCCCGGCAGCTTTGAGGTGCCTATGTTGGCCTGCCAACTGGCGCAGTCCCGCCGTTACGATGCCATC
ATCTGCCTGGGGGCGGTCATTCGGGGCCAAACCCCCCATTTCGACTATGTGGCAGCAGAGGTGGCCAAGGGGATCGCGGC
AGCCAGTTTTCGCACCGGCGTGCCGGTCATCTTCGGGATCCTCACCGCCGATACCCTACAGCAGGCGCTGGAGCGGGCTG
GGATCAAGAACAACAAAGGCTGGGAATACGCCATGAGCGCTCTGGAGATGGCCACCCTGATGCGCCAAGTAGCTCCCCTC
TTGCAAGGGAGCGACAGGGCTGCCAGCAATGGGGCGGCCTCCCGCCCCTCTCTGCCCGGTGGAGCGGAAGCCCTGCAGCC
GGGGGTAACTCTGGAGGGTGCCGCCTACTGA

Upstream 100 bases:

>100_bases
CCCCTTTTTGGGCAGATCTGGAGGAGAAGGGTAAATTAGGATAGGAAGACACGGTTGTGCGGTGTGGAGCAGCGCCTGGT
TTTTTCCCGGAGCAGCGCAG

Downstream 100 bases:

>100_bases
CGGCGGGTTAAACGGGTGAGCACCTCGTTGGAACGCTGCACAAAGGCCCGTGCGGCTGCCGGGTCAAAGCTTTTCTGGGT
AATCAGCGCCAGATCGTAGA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MAVYEGNFVQTGDLRLAIVISRFNDLIAGKLLEGCQDALKRHGIDVSSESQQVDYYWVPGSFEVPMLACQLAQSRRYDAI
ICLGAVIRGQTPHFDYVAAEVAKGIAAASFRTGVPVIFGILTADTLQQALERAGIKNNKGWEYAMSALEMATLMRQVAPL
LQGSDRAASNGAASRPSLPGGAEALQPGVTLEGAAY

Sequences:

>Translated_196_residues
MAVYEGNFVQTGDLRLAIVISRFNDLIAGKLLEGCQDALKRHGIDVSSESQQVDYYWVPGSFEVPMLACQLAQSRRYDAI
ICLGAVIRGQTPHFDYVAAEVAKGIAAASFRTGVPVIFGILTADTLQQALERAGIKNNKGWEYAMSALEMATLMRQVAPL
LQGSDRAASNGAASRPSLPGGAEALQPGVTLEGAAY
>Mature_195_residues
AVYEGNFVQTGDLRLAIVISRFNDLIAGKLLEGCQDALKRHGIDVSSESQQVDYYWVPGSFEVPMLACQLAQSRRYDAII
CLGAVIRGQTPHFDYVAAEVAKGIAAASFRTGVPVIFGILTADTLQQALERAGIKNNKGWEYAMSALEMATLMRQVAPLL
QGSDRAASNGAASRPSLPGGAEALQPGVTLEGAAY

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=158, Percent_Identity=46.2025316455696, Blast_Score=144, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324429, Length=160, Percent_Identity=30.625, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 20907; Mature: 20776

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYEGNFVQTGDLRLAIVISRFNDLIAGKLLEGCQDALKRHGIDVSSESQQVDYYWVPG
CCEECCCEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
SFEVPMLACQLAQSRRYDAIICLGAVIRGQTPHFDYVAAEVAKGIAAASFRTGVPVIFGI
CCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
LTADTLQQALERAGIKNNKGWEYAMSALEMATLMRQVAPLLQGSDRAASNGAASRPSLPG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GAEALQPGVTLEGAAY
CHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AVYEGNFVQTGDLRLAIVISRFNDLIAGKLLEGCQDALKRHGIDVSSESQQVDYYWVPG
CEECCCEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
SFEVPMLACQLAQSRRYDAIICLGAVIRGQTPHFDYVAAEVAKGIAAASFRTGVPVIFGI
CCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
LTADTLQQALERAGIKNNKGWEYAMSALEMATLMRQVAPLLQGSDRAASNGAASRPSLPG
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GAEALQPGVTLEGAAY
CHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA