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The map label for this gene is lpxD

Identifier: 86605713

GI number: 86605713

Start: 1034023

End: 1035054

Strand: Reverse

Name: lpxD

Synonym: CYA_1015

Alternate gene names: 86605713

Gene position: 1035054-1034023 (Counterclockwise)

Preceding gene: 86605714

Following gene: 86605712

Centisome position: 35.29

GC content: 61.92

Gene sequence:

>1032_bases
ATGCAGCTACAGGAGATCGCCCAAAAATTGGGATGCCCCTACGAGGGAGATCCCACCCTAGAAATTCACGGCGTGGCTAG
CCTAGCAGAGGCGCGCCCAGGAGAGCTGAGTTTTCTCAGTGAAGCCCGCTACCTACCCTTGCTGGAGCAGACCCAAGCCA
GCGCCGTCATTGTGGAGGAATCGCTGGTTCTACCCCGCCCCATTGCTTGCCTGCGAGGGAAGGATCCCCGTCTGCTCTTT
GCCCAGGCCATCGAGCTGTTTTACCAGCCCTATCGCTTGCCTGTTGGGATCCATCCCACCGCTGTGATCGATCCCAGCGT
GGAGTTGGGGGAGGGGGTAGCCATTGGGCCCCATGTGGTGGTGATGGAAGGGGTGAAAATTGGCGACTACACCCAAATCC
ACCCCAACGTAACCATCTACCCCCACGTGCGGGTTGGATCCCGGTGTCAGCTTTTCGCCAACTGCGTTATTCACGAGCGC
ACCGAAATTGGCGACGACTGCCTCATCCACAGCGGCGCGGTCATTGGCGACGACGGCTTTGGCCACATTCCTCTTCCCGA
CGGCTCCTGGCGGCGCATGCTGCAGGCAGGCCGGGTGGTGCTGGAAGACGGCGTAGAGGTGGGCAGCAACACCACTATCG
ACCGGGCCGCTGTTGGCGAGACCCGCATTGGCCGGGGCACCAAGATTGACAACCTAGTGCAGATTGGCCACGGCGTGAAG
ACGGGATCCCACTGCTTGATCGTGGCTCAGGTGGGCATTGCCGGCAGCACCCAATTGGGCCACCACGTCATCTTGGCTGG
GCAATGTGGCCTGGCTGGGCACCTGCACATTGGCGATGGCGTACGCGTGGCTGCCCAGACAGGAGTAACCAGCGACGTCC
CCGCTGGTCAAACCGTGGCCGGCTACCCCCACCAACCCATTGCCGAATGGCGTAGGAGCATGGCAGTCCAACGGCATCTG
CCCGAGCTGCAGCGGGCCCTGCGCAAGCTGGAAGCGCGGGTAGCCAAGTTGGAGCAAAACGGTGGGAGGTAA

Upstream 100 bases:

>100_bases
CAAAGTCGGCGTTCCCCTGGAGCTCGAGACCTTTAGCTACAACTTGCGTGGAACCGTGATGGATGTGCGGCTGCTGCAAT
CGTAGAGGATCTCGAGCCTG

Downstream 100 bases:

>100_bases
GGGATCAGGGGTTAACCTGCCGATAGCCAATTCACTTGCTTGCTCCCAACGCCTAACCCAAGAAAACACTCCCCTCACCC
GCCGGCAACTGGCGGAGCTC

Product: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MQLQEIAQKLGCPYEGDPTLEIHGVASLAEARPGELSFLSEARYLPLLEQTQASAVIVEESLVLPRPIACLRGKDPRLLF
AQAIELFYQPYRLPVGIHPTAVIDPSVELGEGVAIGPHVVVMEGVKIGDYTQIHPNVTIYPHVRVGSRCQLFANCVIHER
TEIGDDCLIHSGAVIGDDGFGHIPLPDGSWRRMLQAGRVVLEDGVEVGSNTTIDRAAVGETRIGRGTKIDNLVQIGHGVK
TGSHCLIVAQVGIAGSTQLGHHVILAGQCGLAGHLHIGDGVRVAAQTGVTSDVPAGQTVAGYPHQPIAEWRRSMAVQRHL
PELQRALRKLEARVAKLEQNGGR

Sequences:

>Translated_343_residues
MQLQEIAQKLGCPYEGDPTLEIHGVASLAEARPGELSFLSEARYLPLLEQTQASAVIVEESLVLPRPIACLRGKDPRLLF
AQAIELFYQPYRLPVGIHPTAVIDPSVELGEGVAIGPHVVVMEGVKIGDYTQIHPNVTIYPHVRVGSRCQLFANCVIHER
TEIGDDCLIHSGAVIGDDGFGHIPLPDGSWRRMLQAGRVVLEDGVEVGSNTTIDRAAVGETRIGRGTKIDNLVQIGHGVK
TGSHCLIVAQVGIAGSTQLGHHVILAGQCGLAGHLHIGDGVRVAAQTGVTSDVPAGQTVAGYPHQPIAEWRRSMAVQRHL
PELQRALRKLEARVAKLEQNGGR
>Mature_343_residues
MQLQEIAQKLGCPYEGDPTLEIHGVASLAEARPGELSFLSEARYLPLLEQTQASAVIVEESLVLPRPIACLRGKDPRLLF
AQAIELFYQPYRLPVGIHPTAVIDPSVELGEGVAIGPHVVVMEGVKIGDYTQIHPNVTIYPHVRVGSRCQLFANCVIHER
TEIGDDCLIHSGAVIGDDGFGHIPLPDGSWRRMLQAGRVVLEDGVEVGSNTTIDRAAVGETRIGRGTKIDNLVQIGHGVK
TGSHCLIVAQVGIAGSTQLGHHVILAGQCGLAGHLHIGDGVRVAAQTGVTSDVPAGQTVAGYPHQPIAEWRRSMAVQRHL
PELQRALRKLEARVAKLEQNGGR

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786376, Length=335, Percent_Identity=34.3283582089552, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573 [H]

Pfam domain/function: PF00132 Hexapep; PF04613 LpxD [H]

EC number: 2.3.1.-

Molecular weight: Translated: 36811; Mature: 36811

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLQEIAQKLGCPYEGDPTLEIHGVASLAEARPGELSFLSEARYLPLLEQTQASAVIVEE
CCHHHHHHHHCCCCCCCCCEEEECHHHHHHCCCCCCHHHHCCCCCCHHHHCCCCEEEEEC
SLVLPRPIACLRGKDPRLLFAQAIELFYQPYRLPVGIHPTAVIDPSVELGEGVAIGPHVV
CCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHCCCEEECCEEE
VMEGVKIGDYTQIHPNVTIYPHVRVGSRCQLFANCVIHERTEIGDDCLIHSGAVIGDDGF
EEECEEECCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEECCEEECCCCC
GHIPLPDGSWRRMLQAGRVVLEDGVEVGSNTTIDRAAVGETRIGRGTKIDNLVQIGHGVK
CCCCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCC
TGSHCLIVAQVGIAGSTQLGHHVILAGQCGLAGHLHIGDGVRVAAQTGVTSDVPAGQTVA
CCCCEEEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCCCC
GYPHQPIAEWRRSMAVQRHLPELQRALRKLEARVAKLEQNGGR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLQEIAQKLGCPYEGDPTLEIHGVASLAEARPGELSFLSEARYLPLLEQTQASAVIVEE
CCHHHHHHHHCCCCCCCCCEEEECHHHHHHCCCCCCHHHHCCCCCCHHHHCCCCEEEEEC
SLVLPRPIACLRGKDPRLLFAQAIELFYQPYRLPVGIHPTAVIDPSVELGEGVAIGPHVV
CCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCHHCCCEEECCEEE
VMEGVKIGDYTQIHPNVTIYPHVRVGSRCQLFANCVIHERTEIGDDCLIHSGAVIGDDGF
EEECEEECCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEECCEEECCCCC
GHIPLPDGSWRRMLQAGRVVLEDGVEVGSNTTIDRAAVGETRIGRGTKIDNLVQIGHGVK
CCCCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCC
TGSHCLIVAQVGIAGSTQLGHHVILAGQCGLAGHLHIGDGVRVAAQTGVTSDVPAGQTVA
CCCCEEEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCCCC
GYPHQPIAEWRRSMAVQRHLPELQRALRKLEARVAKLEQNGGR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA