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The map label for this gene is yhdP [H]

Identifier: 86605702

GI number: 86605702

Start: 1016586

End: 1018019

Strand: Reverse

Name: yhdP [H]

Synonym: CYA_1003

Alternate gene names: 86605702

Gene position: 1018019-1016586 (Counterclockwise)

Preceding gene: 86605703

Following gene: 86605700

Centisome position: 34.71

GC content: 60.32

Gene sequence:

>1434_bases
ATGGACGACCCTCCTTTAGCCTCGGCCCCCAGCCCTGAGTTCTCTTGGGGAGAGGCGTCTCTCAGTCTCCTCTGGGTTAT
CGCCCTTCTCCTCATCAACGCTTTTTTTGTGGCGGTGGAGTTTTCCTTGGTGTCGGCGCGGCGCTCCCGCATGGTGCAGC
TGGCCAGCGAAGGGAACCGCCAGGCGGGGATTGTGCAAAAGGCCCAGGAACAGTTGGAGTATGCCCTCTCCACCACCCAG
TTGGGCATTACCCTAGCCAGCGTGCTGCTGGGCTGGATTGGGGCCACCCAGGTTGCGCCGACGCTGTTTTTGGCCTTGAG
GCAGTTGGCTTGGCTTCAGAATGTGGATCCCGCCCTTATCCGGGGAGTGGCAGTGGTGGTGGTGTTTTCGCTGCTCACCT
ATTTCCAAATTGTGGTGGGAGAGCTGATCCCGAAAACTCTGGCCATTCTCTACTCGGAGCCGATTGCGCTGCAACTGGCC
TGGCTTAACCGCTTGGTGAGCCGCTTTTTGCACCCTTTCGTGGAGCTGCTCCGGTTCTCCTCCCGCTGCTTGTTGCAGCT
TTTTGGCGTCCGCATCCCGGAGGCCACTTCTTTTTACAGCACCATGACGGTGGAGGAGCTGCAACTGCTGATTGCCTCGT
CGGTGGAGTCGGGCAACATCGAGGCGGAGGAGCGGGAGCTGTTGAGCAATATTTTCGAGTTCGGCGAGACGGTGGCCAGC
GAGGTGATGATCCCGCGCACCAGCATCGATGCGGTGCCGGAGACGGCCACGGTGCAAGAGGTGCTGGCCGAGGTGGCGGA
ATCGGGGCACTCCCGCTATCCGGTCTACGGCGAGTCTTTGGATGACATCCGCGGGCTGATCCACGTTAAGGAGTTGATCG
GCCAGTTGGCCAAGGGATCCATAGATTTGCACAGCCCCATCACCAACTTCATCCGCGAGGCCCACTTTGAGCCGGAGAAC
AAGCCAATTGCGGAACTGTTGCCCGAAATGAGGCAGCACCACTGGCCGATGGTGGTGCTAGTGGATGAGTTTGGCGGCAC
GGCAGGCCTGATTACCATTCAAGACTTGGTGGAGGAGATCGTCGGCAAGCTCTCCGATGGGCCGGATCCCAAGGCGAAGG
AGGCGGATATTCAGGAGCTGGACGAAAATACCCTCCTCATCCAGGCCCAGTTGGACATTGAAGAGGTCAACGAGCGCTGC
CACCTCAACTTGCCCCTCCACGAGGACTACCAGACCCTGGGGGGCTTTTTGATCTACCACCTGCAGAAGATCCCGCGCGT
GGGGGAAAAGTTTACCTACCAAGACATGGAGTTCCAGGTGGTGCGCATGGAAGGGCCGCGGGTGGATCGGGTGAAGGTCG
TCCGCCACCGCCGCAGCTCTCCCAACCCCCTGCCTTCCCTGCCCCCTGCTCAGACGGCGCAGCCGGGCACTTGA

Upstream 100 bases:

>100_bases
AGCCGCCCGATGGCTGAGGCCAGTTTAACTGCTGGCCAGGGGCAGGTGGTCGAGTCGGTCTGGGCTAAAATGCTCTCTAT
CCGTCTTGCTGCTCCCCCTG

Downstream 100 bases:

>100_bases
GGAGCTAGGTTTTGACGACCTTGAGGGTCTGCAGCCGCACGTCTTCGGGGCCGTTGATAAAGCCGCCTGCCTCGTGCACC
AACAGCAGATAGTCCACCGC

Product: HlyC/CorC (HCC) family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MDDPPLASAPSPEFSWGEASLSLLWVIALLLINAFFVAVEFSLVSARRSRMVQLASEGNRQAGIVQKAQEQLEYALSTTQ
LGITLASVLLGWIGATQVAPTLFLALRQLAWLQNVDPALIRGVAVVVVFSLLTYFQIVVGELIPKTLAILYSEPIALQLA
WLNRLVSRFLHPFVELLRFSSRCLLQLFGVRIPEATSFYSTMTVEELQLLIASSVESGNIEAEERELLSNIFEFGETVAS
EVMIPRTSIDAVPETATVQEVLAEVAESGHSRYPVYGESLDDIRGLIHVKELIGQLAKGSIDLHSPITNFIREAHFEPEN
KPIAELLPEMRQHHWPMVVLVDEFGGTAGLITIQDLVEEIVGKLSDGPDPKAKEADIQELDENTLLIQAQLDIEEVNERC
HLNLPLHEDYQTLGGFLIYHLQKIPRVGEKFTYQDMEFQVVRMEGPRVDRVKVVRHRRSSPNPLPSLPPAQTAQPGT

Sequences:

>Translated_477_residues
MDDPPLASAPSPEFSWGEASLSLLWVIALLLINAFFVAVEFSLVSARRSRMVQLASEGNRQAGIVQKAQEQLEYALSTTQ
LGITLASVLLGWIGATQVAPTLFLALRQLAWLQNVDPALIRGVAVVVVFSLLTYFQIVVGELIPKTLAILYSEPIALQLA
WLNRLVSRFLHPFVELLRFSSRCLLQLFGVRIPEATSFYSTMTVEELQLLIASSVESGNIEAEERELLSNIFEFGETVAS
EVMIPRTSIDAVPETATVQEVLAEVAESGHSRYPVYGESLDDIRGLIHVKELIGQLAKGSIDLHSPITNFIREAHFEPEN
KPIAELLPEMRQHHWPMVVLVDEFGGTAGLITIQDLVEEIVGKLSDGPDPKAKEADIQELDENTLLIQAQLDIEEVNERC
HLNLPLHEDYQTLGGFLIYHLQKIPRVGEKFTYQDMEFQVVRMEGPRVDRVKVVRHRRSSPNPLPSLPPAQTAQPGT
>Mature_477_residues
MDDPPLASAPSPEFSWGEASLSLLWVIALLLINAFFVAVEFSLVSARRSRMVQLASEGNRQAGIVQKAQEQLEYALSTTQ
LGITLASVLLGWIGATQVAPTLFLALRQLAWLQNVDPALIRGVAVVVVFSLLTYFQIVVGELIPKTLAILYSEPIALQLA
WLNRLVSRFLHPFVELLRFSSRCLLQLFGVRIPEATSFYSTMTVEELQLLIASSVESGNIEAEERELLSNIFEFGETVAS
EVMIPRTSIDAVPETATVQEVLAEVAESGHSRYPVYGESLDDIRGLIHVKELIGQLAKGSIDLHSPITNFIREAHFEPEN
KPIAELLPEMRQHHWPMVVLVDEFGGTAGLITIQDLVEEIVGKLSDGPDPKAKEADIQELDENTLLIQAQLDIEEVNERC
HLNLPLHEDYQTLGGFLIYHLQKIPRVGEKFTYQDMEFQVVRMEGPRVDRVKVVRHRRSSPNPLPSLPPAQTAQPGT

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=405, Percent_Identity=35.5555555555556, Blast_Score=235, Evalue=7e-62,
Organism=Escherichia coli, GI1790664, Length=455, Percent_Identity=25.4945054945055, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI145693175, Length=420, Percent_Identity=23.0952380952381, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1786879, Length=249, Percent_Identity=28.9156626506024, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87082033, Length=402, Percent_Identity=26.1194029850746, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788119, Length=244, Percent_Identity=25.8196721311475, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 53091; Mature: 53091

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDPPLASAPSPEFSWGEASLSLLWVIALLLINAFFVAVEFSLVSARRSRMVQLASEGNR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QAGIVQKAQEQLEYALSTTQLGITLASVLLGWIGATQVAPTLFLALRQLAWLQNVDPALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
RGVAVVVVFSLLTYFQIVVGELIPKTLAILYSEPIALQLAWLNRLVSRFLHPFVELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRCLLQLFGVRIPEATSFYSTMTVEELQLLIASSVESGNIEAEERELLSNIFEFGETVAS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
EVMIPRTSIDAVPETATVQEVLAEVAESGHSRYPVYGESLDDIRGLIHVKELIGQLAKGS
HHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
IDLHSPITNFIREAHFEPENKPIAELLPEMRQHHWPMVVLVDEFGGTAGLITIQDLVEEI
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHH
VGKLSDGPDPKAKEADIQELDENTLLIQAQLDIEEVNERCHLNLPLHEDYQTLGGFLIYH
HHHCCCCCCCCCCCCHHHHCCCCEEEEEEECCHHHHCCCEEECCCCHHHHHHHHHHHHHH
LQKIPRVGEKFTYQDMEFQVVRMEGPRVDRVKVVRHRRSSPNPLPSLPPAQTAQPGT
HHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDDPPLASAPSPEFSWGEASLSLLWVIALLLINAFFVAVEFSLVSARRSRMVQLASEGNR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QAGIVQKAQEQLEYALSTTQLGITLASVLLGWIGATQVAPTLFLALRQLAWLQNVDPALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
RGVAVVVVFSLLTYFQIVVGELIPKTLAILYSEPIALQLAWLNRLVSRFLHPFVELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRCLLQLFGVRIPEATSFYSTMTVEELQLLIASSVESGNIEAEERELLSNIFEFGETVAS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
EVMIPRTSIDAVPETATVQEVLAEVAESGHSRYPVYGESLDDIRGLIHVKELIGQLAKGS
HHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
IDLHSPITNFIREAHFEPENKPIAELLPEMRQHHWPMVVLVDEFGGTAGLITIQDLVEEI
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHH
VGKLSDGPDPKAKEADIQELDENTLLIQAQLDIEEVNERCHLNLPLHEDYQTLGGFLIYH
HHHCCCCCCCCCCCCHHHHCCCCEEEEEEECCHHHHCCCEEECCCCHHHHHHHHHHHHHH
LQKIPRVGEKFTYQDMEFQVVRMEGPRVDRVKVVRHRRSSPNPLPSLPPAQTAQPGT
HHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]