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The map label for this gene is mdtH [H]

Identifier: 86605568

GI number: 86605568

Start: 871611

End: 872861

Strand: Reverse

Name: mdtH [H]

Synonym: CYA_0864

Alternate gene names: 86605568

Gene position: 872861-871611 (Counterclockwise)

Preceding gene: 86605569

Following gene: 86605567

Centisome position: 29.76

GC content: 61.39

Gene sequence:

>1251_bases
ATGCGGATCCCGTCCTGGTGGCCAAAGCTAAGTTTTCAGGTTTGGCTAATCTTTATCGGTCGGCTGCTCTCCCAAACCGG
AACCGGCTTTACCCTGTTCTACGCCAGCCTCTTTTTCGTCAATCAGGTGGGGCTGACGGCTACCCAGGTGGGTTTGGGCC
TGGGCTTGATGGCCTTTACTGGCGTATTTGGCCGCATCCTCGGAGGTTCGATGGCAGACGGAGCTTGGGGCCGCCGCTCC
ACCTTGATCCTCTCGCTGGCCATTTCCGCGCTGGGATCCTTCGGCTTTGCCCTTTCCCGTGGCTTCTGGAGCTTTGCCTT
GGCCAACCTGGTGGCGGGGTTTGGGCAGGGCCTCTATTGGCCGCCGGCGGAAGCAATAGTAGCGGATCTAACCCCGCGCG
AGCAGCGCAACGAAGCCTATGCCCTAAACCGCCTGGGGGATAACTTGGGCCTGAGCCTCGGCGTGGCCATGGCCAGCGCC
CTGGTGGCTCTGACGAAGAACTACCGCCTCTTGTTTATTATCGACGGCCTCACGTACTTGATTTTTTTAGCCCTGCTCTG
GCTTTGCATTCGGGAAACTCGGGTAGCTCCGTCGGCGGCAGAGTTCGCAGGCTGGAAAGCCGCCCTGAGGGATCGCCCCC
TATTGGTGTTTGCCGCGGCCAACATTTTCTTCACCACCTACATTGCCCAACTCAGCAGCAGCTTGCCCCTTTACTTGCGC
AAGGGGGCTGGGATGCCTGAGGTACAGATTGGCACGTTGTTTGCTCTGCACGGCGCCCTCGTTGCCCTGCTGCAGATGCC
GGCAGCTCGTTGGCTCAATCGCTGGACGCGTGTCCGCGCCCTCCGGGGATCCGCACTGATGTGGGGGCTGGGATTTGGTT
TGGTTTGGCTCAGCGGCCTGGCGGCCCAGTTGGGAGCGATGCCGGCTATAGGGATGGCGGCCTTGGCCTTGGCAGTGCTC
TCGTTGGCCTTGGTGAGCTACAATCCCTCCGCTTCGGCGCTGGTGGCAGATTTGGCCCCGGATCATCTGCGGGGGGTGTA
TCTGTCGGTCAACTCCCTCTGTTGGGCAGCAGGCTTTGCCCTTGGGCCGCTCATTGGGGGAGTGGCTCTGGATCTGCCGC
CAGCGTGGGCAGGCGGGCTGTGGTTGTTTTGGGTGGCCAGCGTTAGTCTTGTCTGGGGGATCCTTAACGTTTTGGATGGC
CTTCTGCCCCTTCGCGCCAAGGAGGCTGCTCCCCTGGCCAGCAAGCTCTAG

Upstream 100 bases:

>100_bases
AGCCGCTGGCTCCCCCTCAGTTTTCCGCCCGCTGAAGTGGATCTGGCGTCAGCGACCGGGATCCCGTAAGCTAGCTAACC
TATCTCCCGTTGCATCCCCT

Downstream 100 bases:

>100_bases
GAGGAGATGGGCAGCTTGTTAAGCTAATGTTACCTTCAGCTTTCTGAACATGCGTCGTATTTGCATCCTTGGGGGCGGCT
TTGGCGGGCTGTACACAGCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MRIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGLMAFTGVFGRILGGSMADGAWGRRS
TLILSLAISALGSFGFALSRGFWSFALANLVAGFGQGLYWPPAEAIVADLTPREQRNEAYALNRLGDNLGLSLGVAMASA
LVALTKNYRLLFIIDGLTYLIFLALLWLCIRETRVAPSAAEFAGWKAALRDRPLLVFAAANIFFTTYIAQLSSSLPLYLR
KGAGMPEVQIGTLFALHGALVALLQMPAARWLNRWTRVRALRGSALMWGLGFGLVWLSGLAAQLGAMPAIGMAALALAVL
SLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGFALGPLIGGVALDLPPAWAGGLWLFWVASVSLVWGILNVLDG
LLPLRAKEAAPLASKL

Sequences:

>Translated_416_residues
MRIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGLMAFTGVFGRILGGSMADGAWGRRS
TLILSLAISALGSFGFALSRGFWSFALANLVAGFGQGLYWPPAEAIVADLTPREQRNEAYALNRLGDNLGLSLGVAMASA
LVALTKNYRLLFIIDGLTYLIFLALLWLCIRETRVAPSAAEFAGWKAALRDRPLLVFAAANIFFTTYIAQLSSSLPLYLR
KGAGMPEVQIGTLFALHGALVALLQMPAARWLNRWTRVRALRGSALMWGLGFGLVWLSGLAAQLGAMPAIGMAALALAVL
SLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGFALGPLIGGVALDLPPAWAGGLWLFWVASVSLVWGILNVLDG
LLPLRAKEAAPLASKL
>Mature_416_residues
MRIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGLMAFTGVFGRILGGSMADGAWGRRS
TLILSLAISALGSFGFALSRGFWSFALANLVAGFGQGLYWPPAEAIVADLTPREQRNEAYALNRLGDNLGLSLGVAMASA
LVALTKNYRLLFIIDGLTYLIFLALLWLCIRETRVAPSAAEFAGWKAALRDRPLLVFAAANIFFTTYIAQLSSSLPLYLR
KGAGMPEVQIGTLFALHGALVALLQMPAARWLNRWTRVRALRGSALMWGLGFGLVWLSGLAAQLGAMPAIGMAALALAVL
SLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGFALGPLIGGVALDLPPAWAGGLWLFWVASVSLVWGILNVLDG
LLPLRAKEAAPLASKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081828, Length=327, Percent_Identity=25.6880733944954, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787815, Length=361, Percent_Identity=22.7146814404432, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR022855
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44413; Mature: 44413

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGLMAFT
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GVFGRILGGSMADGAWGRRSTLILSLAISALGSFGFALSRGFWSFALANLVAGFGQGLYW
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPAEAIVADLTPREQRNEAYALNRLGDNLGLSLGVAMASALVALTKNYRLLFIIDGLTYL
CCHHHHHHCCCCCHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHH
IFLALLWLCIRETRVAPSAAEFAGWKAALRDRPLLVFAAANIFFTTYIAQLSSSLPLYLR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEE
KGAGMPEVQIGTLFALHGALVALLQMPAARWLNRWTRVRALRGSALMWGLGFGLVWLSGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AAQLGAMPAIGMAALALAVLSLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGFA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LGPLIGGVALDLPPAWAGGLWLFWVASVSLVWGILNVLDGLLPLRAKEAAPLASKL
HHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHCCC
>Mature Secondary Structure
MRIPSWWPKLSFQVWLIFIGRLLSQTGTGFTLFYASLFFVNQVGLTATQVGLGLGLMAFT
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GVFGRILGGSMADGAWGRRSTLILSLAISALGSFGFALSRGFWSFALANLVAGFGQGLYW
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPAEAIVADLTPREQRNEAYALNRLGDNLGLSLGVAMASALVALTKNYRLLFIIDGLTYL
CCHHHHHHCCCCCHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHH
IFLALLWLCIRETRVAPSAAEFAGWKAALRDRPLLVFAAANIFFTTYIAQLSSSLPLYLR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEE
KGAGMPEVQIGTLFALHGALVALLQMPAARWLNRWTRVRALRGSALMWGLGFGLVWLSGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AAQLGAMPAIGMAALALAVLSLALVSYNPSASALVADLAPDHLRGVYLSVNSLCWAAGFA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LGPLIGGVALDLPPAWAGGLWLFWVASVSLVWGILNVLDGLLPLRAKEAAPLASKL
HHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA