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The map label for this gene is ndhH

Identifier: 86605457

GI number: 86605457

Start: 754994

End: 756178

Strand: Reverse

Name: ndhH

Synonym: CYA_0747

Alternate gene names: 86605457

Gene position: 756178-754994 (Counterclockwise)

Preceding gene: 86605459

Following gene: 86605456

Centisome position: 25.78

GC content: 60.17

Gene sequence:

>1185_bases
ATGCCCATGATCGAGACCCGTACTGACCGGATGCTGCTCAACTTTGGGCCGCACCATCCTTCTATGCACGGGGTCTTGCG
CCTGCTGGTCACCCTCGATGGCGAAAACATCGTCGACTGCGAGCCGGTGATTGGCTATCTGCACCGCGGCATGGAAAAAA
TTGCCGAAAACCGCACCGTGGTGCAGTACCTGCCCTACGTCTCCCGCTGGGACTACGGTGCCGGCATGTTCAACGAGGCC
ATCACCGTCAACGCCGTCGAGAAACTGGCTGGGATCCCGGTGCCCCGGCGGGCCAGCTACCTGCGGGTGATCATGTTGGA
GCTGACCCGCATCACCAACCACCTGCTCTGGTTTGGCCCCTTCTTGGCCGACCTGGGCGCCCAAACCCCCTTCCTCTACG
CCATGCGGGAGCGGGAGTGGATCTTGGATTTGTTTGAAGCCGTCACCGGCATGCGCCTCATCAACAACAACTACTTCCGC
GTCGGGGGCGTGGCGGTGGATCTGCCCTACGGCTGGACGGAAAAATGCCTCGATTTTTGCGAGTACTTCCTGCCCAAGGT
AGATGAGTACGAGCGGCTGGTTACCGACAACCCCATCTTCCGCCGGCGGCTGGAAGGGATAGGGGTCATCTCCAAGCAAG
ATGCCATCAACTGGGGCCTGTCTGGGCCCATGCTGCGGGCCTGCGGCGTCAACTGGGATCTGCGCAAGGTGGATCACTAC
GAGTGCTACGACGACTTCGACTGGGAGGTGGCGGTTTACCCAGAGGGGGATTGCCTGGCCCGCTATCGAGTGCGCATGAA
GGAGATGCGCGAGTCCTGCAAAATTGTGCAGCAGGCGGTGAAGGCCCTGCCCGGTGGCCCCTTTGAAAATCTGGAAGCCA
AGCGCATGCTGGAGGGGCCAAAGTCGGAGTGGAACAAGGGCGACTACCAGTTCATCAGCAAAAAGCCCTCGGCCAACTTC
AAGATCCCCAAAGGAGAGGCCTACGTACGGGTGGAGAGCGCCAAAGGGGAGCTGGGGATTTACATTGTTGGCGACGACAA
CGTCTGTCCGTGGCGCTGGAAGATCCGTCCACCCGGCTTTGTCAACCTGCAGGTGTTGCCTCAGCTCATTCGCGGCATGA
AGGTGGCCGACATGATCGCCATCTTGGGCAGCATCGACATCATTATGGGGGAGGTGGATCGCTAA

Upstream 100 bases:

>100_bases
CCTGATGGCCCGAGAGCTCGAGGAACCGCGGGAAAGCCGCTATACTGCAAATGTTGCAGACCATAAACATTCTTCAGTTG
CGGAGGCGGCGGCCATGCCC

Downstream 100 bases:

>100_bases
GATACTCGTAGGAAAGGGAGGACAAGGGCGATGGCCTGGGCGATCTTGCTTCTGCCGCTCCTGATTGTCGTAACTATTGC
CGCGATTATCGGTCCCAAGC

Product: NAD(P)H-quinone oxidoreductase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase subunit H; NADH-plastoquinone oxidoreductase subunit H; NDH-1 subunit H; NDH-H

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MPMIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQYLPYVSRWDYGAGMFNEA
ITVNAVEKLAGIPVPRRASYLRVIMLELTRITNHLLWFGPFLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFR
VGGVAVDLPYGWTEKCLDFCEYFLPKVDEYERLVTDNPIFRRRLEGIGVISKQDAINWGLSGPMLRACGVNWDLRKVDHY
ECYDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKSEWNKGDYQFISKKPSANF
KIPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR

Sequences:

>Translated_394_residues
MPMIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQYLPYVSRWDYGAGMFNEA
ITVNAVEKLAGIPVPRRASYLRVIMLELTRITNHLLWFGPFLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFR
VGGVAVDLPYGWTEKCLDFCEYFLPKVDEYERLVTDNPIFRRRLEGIGVISKQDAINWGLSGPMLRACGVNWDLRKVDHY
ECYDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKSEWNKGDYQFISKKPSANF
KIPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR
>Mature_393_residues
PMIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQYLPYVSRWDYGAGMFNEAI
TVNAVEKLAGIPVPRRASYLRVIMLELTRITNHLLWFGPFLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRV
GGVAVDLPYGWTEKCLDFCEYFLPKVDEYERLVTDNPIFRRRLEGIGVISKQDAINWGLSGPMLRACGVNWDLRKVDHYE
CYDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKSEWNKGDYQFISKKPSANFK
IPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=396, Percent_Identity=41.6666666666667, Blast_Score=304, Evalue=1e-82,
Organism=Homo sapiens, GI260898743, Length=390, Percent_Identity=40.7692307692308, Blast_Score=291, Evalue=1e-78,
Organism=Escherichia coli, GI145693162, Length=393, Percent_Identity=39.6946564885496, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1789076, Length=383, Percent_Identity=28.4595300261097, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788832, Length=393, Percent_Identity=28.7531806615776, Blast_Score=128, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17568379, Length=392, Percent_Identity=41.3265306122449, Blast_Score=316, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17555284, Length=392, Percent_Identity=41.0714285714286, Blast_Score=315, Evalue=2e-86,
Organism=Drosophila melanogaster, GI221459469, Length=396, Percent_Identity=42.9292929292929, Blast_Score=332, Evalue=3e-91,
Organism=Drosophila melanogaster, GI24638644, Length=393, Percent_Identity=39.9491094147583, Blast_Score=322, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NDHH_SYNJA (Q2JWB1)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474220.1
- HSSP:   Q56220
- ProteinModelPortal:   Q2JWB1
- SMR:   Q2JWB1
- STRING:   Q2JWB1
- GeneID:   3897084
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0747
- TIGR:   CYA_0747
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   FGPFLAD
- ProtClustDB:   PRK07415
- BioCyc:   SSP321327:CYA_0747-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: 1.6.5.3

Molecular weight: Translated: 45251; Mature: 45120

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTV
CCCCCCCCCEEEEECCCCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCHH
VQYLPYVSRWDYGAGMFNEAITVNAVEKLAGIPVPRRASYLRVIMLELTRITNHLLWFGP
HHHCCHHHCCCCCCCHHCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVGGVAVDLPYGWTEKCLDFC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCHHHHHHHH
EYFLPKVDEYERLVTDNPIFRRRLEGIGVISKQDAINWGLSGPMLRACGVNWDLRKVDHY
HHHCCCCHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCC
ECYDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGP
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCC
KSEWNKGDYQFISKKPSANFKIPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGF
CCCCCCCCEEEEECCCCCCEECCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCE
VNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR
EHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCC
>Mature Secondary Structure 
PMIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTV
CCCCCCCCEEEEECCCCCCCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCHH
VQYLPYVSRWDYGAGMFNEAITVNAVEKLAGIPVPRRASYLRVIMLELTRITNHLLWFGP
HHHCCHHHCCCCCCCHHCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVGGVAVDLPYGWTEKCLDFC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCHHHHHHHH
EYFLPKVDEYERLVTDNPIFRRRLEGIGVISKQDAINWGLSGPMLRACGVNWDLRKVDHY
HHHCCCCHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCC
ECYDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGP
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCC
KSEWNKGDYQFISKKPSANFKIPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGF
CCCCCCCCEEEEECCCCCCEECCCCCEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCE
VNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR
EHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA