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The map label for this gene is 86605293

Identifier: 86605293

GI number: 86605293

Start: 589986

End: 590897

Strand: Reverse

Name: 86605293

Synonym: CYA_0576

Alternate gene names: NA

Gene position: 590897-589986 (Counterclockwise)

Preceding gene: 86605294

Following gene: 86605289

Centisome position: 20.15

GC content: 63.71

Gene sequence:

>912_bases
ATGTTGCCCGTTTACTATTCTGAGACTTTTCTCCGCCACGACGCCGGGCCGTTTCACCCCGAGCGTCCGGCTCGCCTGCA
GGCCATTGTCAAGGCGCTGCGCGGTGCCTCTTTCGCCGAGCATCTGGAATGGCGGGATCCCCCCTTGGCCGATCTTGCAC
AACTGGAGCGGGTACACCCGCGCTGGCACATTCAACGGGTGGCCGAGTTGGCTGAGGCAGGAGGGGGTCGCCTCGATGCC
GATACCGCCGTTTCCCCAGCGAGCTTTGAGGCGGCGCGGCAGGCAGTTGGAGCCTGGATTGCTGCTTCGGCCTCGGCTTT
GGCCGCGGCTCAGCCTGCTTTGGTGCTGTGTCGCCCGCCGGGGCATCACGCGGAGCCGGAACGGGCAATGGGGTTTTGTC
TCTTCAGTAACGCCGCCATTGCCGCCCTCTGGGCCCTGGATCAGCCGGGGGTGAGGCGGGTAGCCATTTTCGATTGGGAT
GTGCACCACGGCAACGGCACGCAGGCGGTGGTGGAGCGTCACCCCCAACTGGCCTATGCCTCTATCCATCAGTTTCCCCT
CTACCCTGGCACGGGCTTGGCCGAGGAAACCGGGATCCACGGCAACCTCTGCAACGTGCCTCTGCCTGCCAGGTCAGACT
GGTCGGTCTACAAAAAAGCTCTCGATGAGAAGGTCTTGCCGTTTTTGCGGGCCTTCCAACCGGATTTGCTGCTGGTGAGC
GCCGGCTTTGACTGTGCCAAAGGGGATCCCTTGGCCAGTATGCTGCTGGAGCCGGAAGACTTTGGCCGCATGGCCCACCT
CTGCCTGGAGGAGGTGACCCGCAAGACCGTCTTCGGGTTAGAAGGGGGCTATGACCTGGAGAATCTGGCCCGCGGCTGGC
TGAGCCTGGCCCAAGCTTGCCTGGAGAGCTAG

Upstream 100 bases:

>100_bases
TTTGGCGTTGATCCCTATGCGGGATCCATGTCGGAAGCCTTCTACGGGTAGAGGGAAGATGGGCTTAGGCTAGACTGCAA
GAACGCTACCTTGCCCTGGT

Downstream 100 bases:

>100_bases
CCCTTCCACTTCACCTTGGGCAGGATCTGCCGCACATCCACGCGGTCTTTGTACTTGAGGGCGAAGTTGAGCAGCGAGTC
CAAAAGCGAGTCAGATAGGT

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLPVYYSETFLRHDAGPFHPERPARLQAIVKALRGASFAEHLEWRDPPLADLAQLERVHPRWHIQRVAELAEAGGGRLDA
DTAVSPASFEAARQAVGAWIAASASALAAAQPALVLCRPPGHHAEPERAMGFCLFSNAAIAALWALDQPGVRRVAIFDWD
VHHGNGTQAVVERHPQLAYASIHQFPLYPGTGLAEETGIHGNLCNVPLPARSDWSVYKKALDEKVLPFLRAFQPDLLLVS
AGFDCAKGDPLASMLLEPEDFGRMAHLCLEEVTRKTVFGLEGGYDLENLARGWLSLAQACLES

Sequences:

>Translated_303_residues
MLPVYYSETFLRHDAGPFHPERPARLQAIVKALRGASFAEHLEWRDPPLADLAQLERVHPRWHIQRVAELAEAGGGRLDA
DTAVSPASFEAARQAVGAWIAASASALAAAQPALVLCRPPGHHAEPERAMGFCLFSNAAIAALWALDQPGVRRVAIFDWD
VHHGNGTQAVVERHPQLAYASIHQFPLYPGTGLAEETGIHGNLCNVPLPARSDWSVYKKALDEKVLPFLRAFQPDLLLVS
AGFDCAKGDPLASMLLEPEDFGRMAHLCLEEVTRKTVFGLEGGYDLENLARGWLSLAQACLES
>Mature_303_residues
MLPVYYSETFLRHDAGPFHPERPARLQAIVKALRGASFAEHLEWRDPPLADLAQLERVHPRWHIQRVAELAEAGGGRLDA
DTAVSPASFEAARQAVGAWIAASASALAAAQPALVLCRPPGHHAEPERAMGFCLFSNAAIAALWALDQPGVRRVAIFDWD
VHHGNGTQAVVERHPQLAYASIHQFPLYPGTGLAEETGIHGNLCNVPLPARSDWSVYKKALDEKVLPFLRAFQPDLLLVS
AGFDCAKGDPLASMLLEPEDFGRMAHLCLEEVTRKTVFGLEGGYDLENLARGWLSLAQACLES

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=318, Percent_Identity=32.3899371069182, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI17158039, Length=325, Percent_Identity=31.3846153846154, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI30795202, Length=325, Percent_Identity=31.3846153846154, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI30795204, Length=325, Percent_Identity=31.3846153846154, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI148539870, Length=330, Percent_Identity=32.1212121212121, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI169234807, Length=330, Percent_Identity=32.1212121212121, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI20070354, Length=300, Percent_Identity=34.3333333333333, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI62750347, Length=324, Percent_Identity=30.8641975308642, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI62750349, Length=324, Percent_Identity=30.8641975308642, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI153085395, Length=324, Percent_Identity=31.1728395061728, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI226529806, Length=294, Percent_Identity=30.6122448979592, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI8923769, Length=318, Percent_Identity=23.8993710691824, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI13128860, Length=316, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI262073088, Length=185, Percent_Identity=26.4864864864865, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI13128862, Length=308, Percent_Identity=27.9220779220779, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI293336691, Length=303, Percent_Identity=23.7623762376238, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=307, Percent_Identity=32.8990228013029, Blast_Score=151, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI193209491, Length=335, Percent_Identity=33.7313432835821, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17540332, Length=309, Percent_Identity=33.0097087378641, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI193206283, Length=309, Percent_Identity=33.0097087378641, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17537347, Length=302, Percent_Identity=35.7615894039735, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25154020, Length=311, Percent_Identity=28.6173633440514, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25154022, Length=311, Percent_Identity=28.2958199356913, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17508561, Length=310, Percent_Identity=24.8387096774194, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17534739, Length=303, Percent_Identity=24.0924092409241, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324307, Length=318, Percent_Identity=34.5911949685535, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6325325, Length=164, Percent_Identity=26.219512195122, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323999, Length=302, Percent_Identity=22.1854304635762, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325141, Length=229, Percent_Identity=25.764192139738, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281360899, Length=294, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24642142, Length=300, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24642144, Length=300, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24642146, Length=300, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24641720, Length=306, Percent_Identity=35.6209150326797, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281360801, Length=306, Percent_Identity=35.6209150326797, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281360799, Length=306, Percent_Identity=35.6209150326797, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24657891, Length=308, Percent_Identity=24.6753246753247, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644244, Length=309, Percent_Identity=25.5663430420712, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649807, Length=301, Percent_Identity=24.2524916943522, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33058; Mature: 33058

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVYYSETFLRHDAGPFHPERPARLQAIVKALRGASFAEHLEWRDPPLADLAQLERVHP
CCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHCH
RWHIQRVAELAEAGGGRLDADTAVSPASFEAARQAVGAWIAASASALAAAQPALVLCRPP
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GHHAEPERAMGFCLFSNAAIAALWALDQPGVRRVAIFDWDVHHGNGTQAVVERHPQLAYA
CCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHCCCCHHHH
SIHQFPLYPGTGLAEETGIHGNLCNVPLPARSDWSVYKKALDEKVLPFLRAFQPDLLLVS
HHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGFDCAKGDPLASMLLEPEDFGRMAHLCLEEVTRKTVFGLEGGYDLENLARGWLSLAQAC
CCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LES
HCC
>Mature Secondary Structure
MLPVYYSETFLRHDAGPFHPERPARLQAIVKALRGASFAEHLEWRDPPLADLAQLERVHP
CCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHCH
RWHIQRVAELAEAGGGRLDADTAVSPASFEAARQAVGAWIAASASALAAAQPALVLCRPP
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GHHAEPERAMGFCLFSNAAIAALWALDQPGVRRVAIFDWDVHHGNGTQAVVERHPQLAYA
CCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEEEEEEECCCCCHHHHHCCCCHHHH
SIHQFPLYPGTGLAEETGIHGNLCNVPLPARSDWSVYKKALDEKVLPFLRAFQPDLLLVS
HHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
AGFDCAKGDPLASMLLEPEDFGRMAHLCLEEVTRKTVFGLEGGYDLENLARGWLSLAQAC
CCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LES
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]