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The map label for this gene is ppnK

Identifier: 86605004

GI number: 86605004

Start: 291655

End: 292578

Strand: Reverse

Name: ppnK

Synonym: CYA_0282

Alternate gene names: 86605004

Gene position: 292578-291655 (Counterclockwise)

Preceding gene: 86605008

Following gene: 86604992

Centisome position: 9.98

GC content: 62.12

Gene sequence:

>924_bases
ATGAGCAAGCCCAAAGCCGGGATCCTCTACAACGACGCCAAGCCCGCCGCCAAGCGCAGCAGCGAAACCCTGTCCCGCTG
GTTTCAGGAACAGGGTTGGGAAGTCTGTGTCGCACCCAACTGGGGCGGCATCCTTGGCTACGCCAAGCCCGACAGTCCCG
TCTGCTTGACCAAGGTGGACAGCCTGGCCCCCGCCGGCTTTGACGAGAGCATGAAGTTTGCCGTGGTGCTGGGGGGAGAC
GGCACCGTTTTGGCAGCAGCCCGGCAACTGGCCCCCAAAGGGATCCCCTTGCTGGCCGTGAACACGGGCCACCTGGGCTT
TCTGACAGAGACCTACCTAACCCACCTGGAGGAGGCGGCCAAGGCAGCCATTGCTGGCGAGTACATTCTCGATCGCCGCA
GCATGTTGCTGGTGCAGGCCTACCGCGGCAACGAATTGCGCTGGGAGGTGCTCAGCCTCAACGAGATGGTGCTCCACCGC
GAGCCCTTGACCAGCATGTGCCACTTTGAAGTAACCATTGGGGATCACTCACCGCTGGATGTGGCTGCCGACGGCATTAT
TTTAGCCACCCCCACCGGTTCCACCGCCTATGCCCTTTCTGCGGGAGGGCCGGTCATCACTCCCGGCCTGCCGGTGTTGC
AGTTGATCCCTATCTGTCCCCACTCGATGGCCTCACGGGCTCTGGTCTTTCCCGATTCGGAAGAGGTATGGATCAGCCCC
GCCAGCCCTCAGCCGCTGGTTTTGGTAGCGGACGGCAATGCCGGCTGCTACATCCTGCCAGAAGACCAAATTCGCGTTGT
CCGCGCCCCCTACTGCACAGATTTGATTCGCCTACGCCGACCGGAGTTTTTCCGCGTCATGCGGGAGAAATTGGGCTGGG
GCCTAACCTACGCCTCCAAGCCCACCTCGGTAGAGCTGCCTTAG

Upstream 100 bases:

>100_bases
CACCAAAACCCGAGACCGCTGCCGTCCTGGTTACAGAAGGGATCCCAGAGCCGATCCAGAACTGATAGAGTTTTGGCACC
CTCTGCCTCACCACTGCCCC

Downstream 100 bases:

>100_bases
TTAGAAAACTTAAATGAGGAGGGGCTGTCGACTTCGATGGGGCCCAGCCCTCTTTTTTGCACCAGGGTTTGCAGCTCGTG
CACAAGGTGTTGATCTCGGG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSKPKAGILYNDAKPAAKRSSETLSRWFQEQGWEVCVAPNWGGILGYAKPDSPVCLTKVDSLAPAGFDESMKFAVVLGGD
GTVLAAARQLAPKGIPLLAVNTGHLGFLTETYLTHLEEAAKAAIAGEYILDRRSMLLVQAYRGNELRWEVLSLNEMVLHR
EPLTSMCHFEVTIGDHSPLDVAADGIILATPTGSTAYALSAGGPVITPGLPVLQLIPICPHSMASRALVFPDSEEVWISP
ASPQPLVLVADGNAGCYILPEDQIRVVRAPYCTDLIRLRRPEFFRVMREKLGWGLTYASKPTSVELP

Sequences:

>Translated_307_residues
MSKPKAGILYNDAKPAAKRSSETLSRWFQEQGWEVCVAPNWGGILGYAKPDSPVCLTKVDSLAPAGFDESMKFAVVLGGD
GTVLAAARQLAPKGIPLLAVNTGHLGFLTETYLTHLEEAAKAAIAGEYILDRRSMLLVQAYRGNELRWEVLSLNEMVLHR
EPLTSMCHFEVTIGDHSPLDVAADGIILATPTGSTAYALSAGGPVITPGLPVLQLIPICPHSMASRALVFPDSEEVWISP
ASPQPLVLVADGNAGCYILPEDQIRVVRAPYCTDLIRLRRPEFFRVMREKLGWGLTYASKPTSVELP
>Mature_306_residues
SKPKAGILYNDAKPAAKRSSETLSRWFQEQGWEVCVAPNWGGILGYAKPDSPVCLTKVDSLAPAGFDESMKFAVVLGGDG
TVLAAARQLAPKGIPLLAVNTGHLGFLTETYLTHLEEAAKAAIAGEYILDRRSMLLVQAYRGNELRWEVLSLNEMVLHRE
PLTSMCHFEVTIGDHSPLDVAADGIILATPTGSTAYALSAGGPVITPGLPVLQLIPICPHSMASRALVFPDSEEVWISPA
SPQPLVLVADGNAGCYILPEDQIRVVRAPYCTDLIRLRRPEFFRVMREKLGWGLTYASKPTSVELP

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=259, Percent_Identity=29.3436293436293, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1788968, Length=288, Percent_Identity=32.6388888888889, Blast_Score=152, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320794, Length=251, Percent_Identity=31.0756972111554, Blast_Score=119, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6322509, Length=251, Percent_Identity=32.2709163346614, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6325068, Length=170, Percent_Identity=32.9411764705882, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573828, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28573830, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573832, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161077047, Length=223, Percent_Identity=31.8385650224215, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573826, Length=223, Percent_Identity=31.8385650224215, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129957, Length=279, Percent_Identity=28.3154121863799, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24653422, Length=283, Percent_Identity=28.6219081272085, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281363321, Length=279, Percent_Identity=28.3154121863799, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363323, Length=279, Percent_Identity=28.3154121863799, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24653424, Length=279, Percent_Identity=28.3154121863799, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33248; Mature: 33117

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPKAGILYNDAKPAAKRSSETLSRWFQEQGWEVCVAPNWGGILGYAKPDSPVCLTKVD
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCEEEEEHH
SLAPAGFDESMKFAVVLGGDGTVLAAARQLAPKGIPLLAVNTGHLGFLTETYLTHLEEAA
HCCCCCCCCCEEEEEEECCCCCEEHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
KAAIAGEYILDRRSMLLVQAYRGNELRWEVLSLNEMVLHREPLTSMCHFEVTIGDHSPLD
HHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEHHHHHHCCCCCCCEEEEEEEECCCCCCC
VAADGIILATPTGSTAYALSAGGPVITPGLPVLQLIPICPHSMASRALVFPDSEEVWISP
EECCCEEEECCCCCCEEEEECCCCEECCCCCHHHHCCCCCHHHHCCEEECCCCCCEEEEC
ASPQPLVLVADGNAGCYILPEDQIRVVRAPYCTDLIRLRRPEFFRVMREKLGWGLTYASK
CCCCCEEEEEECCCCEEEECCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCEEECCC
PTSVELP
CCEECCC
>Mature Secondary Structure 
SKPKAGILYNDAKPAAKRSSETLSRWFQEQGWEVCVAPNWGGILGYAKPDSPVCLTKVD
CCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCCEEEEEHH
SLAPAGFDESMKFAVVLGGDGTVLAAARQLAPKGIPLLAVNTGHLGFLTETYLTHLEEAA
HCCCCCCCCCEEEEEEECCCCCEEHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
KAAIAGEYILDRRSMLLVQAYRGNELRWEVLSLNEMVLHREPLTSMCHFEVTIGDHSPLD
HHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEHHHHHHCCCCCCCEEEEEEEECCCCCCC
VAADGIILATPTGSTAYALSAGGPVITPGLPVLQLIPICPHSMASRALVFPDSEEVWISP
EECCCEEEECCCCCCEEEEECCCCEECCCCCHHHHCCCCCHHHHCCEEECCCCCCEEEEC
ASPQPLVLVADGNAGCYILPEDQIRVVRAPYCTDLIRLRRPEFFRVMREKLGWGLTYASK
CCCCCEEEEEECCCCEEEECCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCEEECCC
PTSVELP
CCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA