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The map label for this gene is uvrC

Identifier: 86604931

GI number: 86604931

Start: 211884

End: 213749

Strand: Reverse

Name: uvrC

Synonym: CYA_0207

Alternate gene names: 86604931

Gene position: 213749-211884 (Counterclockwise)

Preceding gene: 86604932

Following gene: 86604930

Centisome position: 7.29

GC content: 58.2

Gene sequence:

>1866_bases
ATGACTGTCCCTCTGATTCAAAACCCTGAGGTTCTAGAAAGCCGCCTTAAGGAGATTCCTGCCGAACCTGGTGTCTATTT
GATGCGGGATGCCACCGACCAGATTCTCTATGTGGGCAAATCCAAAAAGTTGCGATCTCGCGTGCGATCCTATTTTCGCT
TTACCGGCGACCTGTCTCCTCGTATTCAGCGCATGGTAGTTCAGGTTTGCGAGATCGAGTTTATCGTCACTGATAACGAA
AGCGAAGCTCTAGCCCTGGAAGACAATCTCATTAAAACCTATCAGCCGCCCTACAATGTTCTCCTCAAAGAGGATAAAAA
ATACCCCTATTTGTGCATTACGTGGTCAGAGCCTTACCCGCAGATTTACATTACCCGCCACCGCCGTCTCAACCAAAATC
AAGATAAGTACTACGGGCCCTATACCGATGTGGGCCTGCTGCGTTACACCCTCGGTCTGGTAAAGCGCATTTTTCCCTTG
CGCCAGCGCCCCAAGCCGCTTTACAAGGACCGCCCCTGTTTGAACTATGACATCGGGCGTTGCCCTGGTGTCTGTCAGGG
CTTGATTAGCCCGGAAGCGTATCGCAAGACCGTTGCTCAAGTGGCGATGATCTTCCAAGGCCAGACGGACGAGCTTATCC
GTGAGTTGAAGGAGAAAATGGCCCAGGCAGCGCAGCAAGAAAACTATGAGGCGGCGGCGCGCTATCGGGATCAAATCCGC
GGCCTAGAGCAACTGGGCCAATCCCAGAAGGTCTCTTTGCCCAACTCTACCGCCAGCCGCGATGCCATAGCTTTGGCCAT
GAACGACTCGCGGGCTTGCATCCAGTTGTTTCAGGTGCGGGCGGGCAAGTTGGTGGGACGGCTAGGGTTTGTGGCCGAAA
ACCGCGGCGACGACCCGGCTCTTATTTTGCAGCGGGTTTTGCAGGAACATTACCAATATTGCGACCCGGTGGAAATTCCC
TCCGAGATTTTGACCCAGTATGAGTTGCCGGATCGCGATTTTTTGGAATCTTGGCTGAGCCAGAAAAAGGGGCGCAAGGT
CAGCCTCCTTGCCCCGCAGCGGCAGAGCAAAGCCGAGCTAATCGAACTGGTGGAGCGGAACGCCCAGCTAGAGCTAGCCC
GCAGCCAGCGCCTGGCGGAGCGGGAGGCAGCAGCGCTGGAGCGCTTGGCGGAAGTTTTGGATCTGCCAGAGCCGCCCCGT
CGCCTAGAAGCCTACGACATCTCCCACATCCAGGGATCCGACGCTGTGGGCAGCCAGGTGGTGTTTATCGATGGCCTGCC
GGCCAAGCAACACTACCGCCGCTACAAGATTCGCAACCCCCAGGTGCGGCCTGGCCACTCCGACGACTTTGCCAGCCATG
CCGAGGTGGCGCGGCGTCGCTTCAGCAAGATGACTTCCGAGGATCAGCCGGACTTGGTGCTCATCGACGGGGGCAAGGGG
CAACTGGCAGCAGTGATGGCCGTCTTGGCAGAGCTGGGGCTGGATCACCTGCCGGTCTTTGCCCTGGCCAAGCGGGAAGA
GGAGATCTTTCGGCCTGGGGATCCTGAGCCGCTGCGGCTGCCGCCCCAGGATCCGGCCCGCCTGCTGTTGCAGCGTCTGC
GGGATGAGGCCCACCGCTTTGCCCTTGCCTACCATCGCCAGCAGCGGAAACTACGCCAACAGGCTTCGGTTCTGGAGGAG
ATCCCTGGTCTAGGCAAGCAGCGGCAAAAGCTGCTCATGGAGGCGTTTCGCTCCCTTGCCCGCATTCAAGTGGCTACGGA
AGAGCAGTTGGCCCAGGTGCCAGGCATTGGCCCCAAGCTGGCCCGCCAGATCTACCGCTACTTCCATCCAGAAGCCGAAA
CAGAGTTGCCAGCAACAGCGGAGTAG

Upstream 100 bases:

>100_bases
AGCCAACTGGGCGATGGGATGATTTTAAGATGGGAGTGACTTGGTCATCACTGAATGAAAGCCTTGGGATCCCTGGCTTT
GCCTGTTGGAGCGAAGCTGT

Downstream 100 bases:

>100_bases
CCGACCCGCCTGTGGGCAAGCCGAACGACCTGAGCTGGCCTATCATCGTGGAGTCCGCCATTCTCGGCCAAGGGGGCCAA
GTGAAGGTAGCGCTGTTGCA

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MTVPLIQNPEVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTGDLSPRIQRMVVQVCEIEFIVTDNE
SEALALEDNLIKTYQPPYNVLLKEDKKYPYLCITWSEPYPQIYITRHRRLNQNQDKYYGPYTDVGLLRYTLGLVKRIFPL
RQRPKPLYKDRPCLNYDIGRCPGVCQGLISPEAYRKTVAQVAMIFQGQTDELIRELKEKMAQAAQQENYEAAARYRDQIR
GLEQLGQSQKVSLPNSTASRDAIALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPALILQRVLQEHYQYCDPVEIP
SEILTQYELPDRDFLESWLSQKKGRKVSLLAPQRQSKAELIELVERNAQLELARSQRLAEREAAALERLAEVLDLPEPPR
RLEAYDISHIQGSDAVGSQVVFIDGLPAKQHYRRYKIRNPQVRPGHSDDFASHAEVARRRFSKMTSEDQPDLVLIDGGKG
QLAAVMAVLAELGLDHLPVFALAKREEEIFRPGDPEPLRLPPQDPARLLLQRLRDEAHRFALAYHRQQRKLRQQASVLEE
IPGLGKQRQKLLMEAFRSLARIQVATEEQLAQVPGIGPKLARQIYRYFHPEAETELPATAE

Sequences:

>Translated_621_residues
MTVPLIQNPEVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTGDLSPRIQRMVVQVCEIEFIVTDNE
SEALALEDNLIKTYQPPYNVLLKEDKKYPYLCITWSEPYPQIYITRHRRLNQNQDKYYGPYTDVGLLRYTLGLVKRIFPL
RQRPKPLYKDRPCLNYDIGRCPGVCQGLISPEAYRKTVAQVAMIFQGQTDELIRELKEKMAQAAQQENYEAAARYRDQIR
GLEQLGQSQKVSLPNSTASRDAIALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPALILQRVLQEHYQYCDPVEIP
SEILTQYELPDRDFLESWLSQKKGRKVSLLAPQRQSKAELIELVERNAQLELARSQRLAEREAAALERLAEVLDLPEPPR
RLEAYDISHIQGSDAVGSQVVFIDGLPAKQHYRRYKIRNPQVRPGHSDDFASHAEVARRRFSKMTSEDQPDLVLIDGGKG
QLAAVMAVLAELGLDHLPVFALAKREEEIFRPGDPEPLRLPPQDPARLLLQRLRDEAHRFALAYHRQQRKLRQQASVLEE
IPGLGKQRQKLLMEAFRSLARIQVATEEQLAQVPGIGPKLARQIYRYFHPEAETELPATAE
>Mature_620_residues
TVPLIQNPEVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTGDLSPRIQRMVVQVCEIEFIVTDNES
EALALEDNLIKTYQPPYNVLLKEDKKYPYLCITWSEPYPQIYITRHRRLNQNQDKYYGPYTDVGLLRYTLGLVKRIFPLR
QRPKPLYKDRPCLNYDIGRCPGVCQGLISPEAYRKTVAQVAMIFQGQTDELIRELKEKMAQAAQQENYEAAARYRDQIRG
LEQLGQSQKVSLPNSTASRDAIALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPALILQRVLQEHYQYCDPVEIPS
EILTQYELPDRDFLESWLSQKKGRKVSLLAPQRQSKAELIELVERNAQLELARSQRLAEREAAALERLAEVLDLPEPPRR
LEAYDISHIQGSDAVGSQVVFIDGLPAKQHYRRYKIRNPQVRPGHSDDFASHAEVARRRFSKMTSEDQPDLVLIDGGKGQ
LAAVMAVLAELGLDHLPVFALAKREEEIFRPGDPEPLRLPPQDPARLLLQRLRDEAHRFALAYHRQQRKLRQQASVLEEI
PGLGKQRQKLLMEAFRSLARIQVATEEQLAQVPGIGPKLARQIYRYFHPEAETELPATAE

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=608, Percent_Identity=36.6776315789474, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1788037, Length=204, Percent_Identity=30.3921568627451, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF00633 HHH; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 71206; Mature: 71075

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPLIQNPEVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTGDLSP
CCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCCH
RIQRMVVQVCEIEFIVTDNESEALALEDNLIKTYQPPYNVLLKEDKKYPYLCITWSEPYP
HHHHHHHHHHHEEEEEECCCCCEEEECCCHHHHCCCCHHHHEECCCCCCEEEEEECCCCC
QIYITRHRRLNQNQDKYYGPYTDVGLLRYTLGLVKRIFPLRQRPKPLYKDRPCLNYDIGR
EEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
CPGVCQGLISPEAYRKTVAQVAMIFQGQTDELIRELKEKMAQAAQQENYEAAARYRDQIR
CCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GLEQLGQSQKVSLPNSTASRDAIALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPA
HHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LILQRVLQEHYQYCDPVEIPSEILTQYELPDRDFLESWLSQKKGRKVSLLAPQRQSKAEL
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHH
IELVERNAQLELARSQRLAEREAAALERLAEVLDLPEPPRRLEAYDISHIQGSDAVGSQV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCHHCCCCCCCCCCCCCEE
VFIDGLPAKQHYRRYKIRNPQVRPGHSDDFASHAEVARRRFSKMTSEDQPDLVLIDGGKG
EEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
QLAAVMAVLAELGLDHLPVFALAKREEEIFRPGDPEPLRLPPQDPARLLLQRLRDEAHRF
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ALAYHRQQRKLRQQASVLEEIPGLGKQRQKLLMEAFRSLARIQVATEEQLAQVPGIGPKL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ARQIYRYFHPEAETELPATAE
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TVPLIQNPEVLESRLKEIPAEPGVYLMRDATDQILYVGKSKKLRSRVRSYFRFTGDLSP
CCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCCH
RIQRMVVQVCEIEFIVTDNESEALALEDNLIKTYQPPYNVLLKEDKKYPYLCITWSEPYP
HHHHHHHHHHHEEEEEECCCCCEEEECCCHHHHCCCCHHHHEECCCCCCEEEEEECCCCC
QIYITRHRRLNQNQDKYYGPYTDVGLLRYTLGLVKRIFPLRQRPKPLYKDRPCLNYDIGR
EEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
CPGVCQGLISPEAYRKTVAQVAMIFQGQTDELIRELKEKMAQAAQQENYEAAARYRDQIR
CCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GLEQLGQSQKVSLPNSTASRDAIALAMNDSRACIQLFQVRAGKLVGRLGFVAENRGDDPA
HHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LILQRVLQEHYQYCDPVEIPSEILTQYELPDRDFLESWLSQKKGRKVSLLAPQRQSKAEL
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHH
IELVERNAQLELARSQRLAEREAAALERLAEVLDLPEPPRRLEAYDISHIQGSDAVGSQV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCHHCCCCCCCCCCCCCEE
VFIDGLPAKQHYRRYKIRNPQVRPGHSDDFASHAEVARRRFSKMTSEDQPDLVLIDGGKG
EEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
QLAAVMAVLAELGLDHLPVFALAKREEEIFRPGDPEPLRLPPQDPARLLLQRLRDEAHRF
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ALAYHRQQRKLRQQASVLEEIPGLGKQRQKLLMEAFRSLARIQVATEEQLAQVPGIGPKL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ARQIYRYFHPEAETELPATAE
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA