Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 86361259

GI number: 86361259

Start: 594574

End: 595299

Strand: Direct

Name: ompR [H]

Synonym: RHE_PF00530

Alternate gene names: 86361259

Gene position: 594574-595299 (Clockwise)

Preceding gene: 86361258

Following gene: 86361260

Centisome position: 92.54

GC content: 63.36

Gene sequence:

>726_bases
ATGGCAGCACCTCAGCATGACGCGCACCTTCTCGTCGTCGATGACGATCCGCGCATACGCCAAATGTTGACGCGCTATTT
CGAGGATGAAGGTTATACGGTCTCTTCCGCTGCCGACGGCACCGAGATGCGCGTGCGCCTGCGCCAGCAGAACTTCGACG
CCGTCCTGCTCGATCTCGTTCTCCCGGGCGGCACGGATGGCCTTGACCTGGCCCGCGAAATCCGCGCCCAGTCCGACGTC
CCGATCATGATGCTGACCGGCCGCGACGACGTCGTCGACCGAATTGTCGGTCTGGAGGTCGGCGCCGACGATTACATCGC
CAAGCCCTTCCATCTCCGGGAAGTCCATGCGCGCCTGAAATCGATCCTGCGCCGCCGGCAACCTCCCGCGCGCAACCCCG
AAGCGGCCGGCGAGGAGATCATCGGCTTCGAGGACTGGAAGCTCAATCTCAGCCGCCGCCAACTGCTCGACCCCGAGGGT
ACGGAGATCGAACTGACGACTGGCGAATTCGATATGCTGACGACCTTCGTGCGGCATGCCGGCCGGGTCCTGACCCGCGA
CGTGCTGATGGACCTGACCAGGGGCCGAAACCTCGAAGCCTTTGACCGGACGATCGATGCCCAGATCGTCCGGCTGCGCC
GAAAGATCGAAACCGACCCGAAGAAGCCGCAATTCATCAAGGCGGTGCGCGGCGTCGGCTATGTCTTTACCGCAAGACTC
GACTAG

Upstream 100 bases:

>100_bases
GGACAACCGACCGGTGGCTGGTGACACCAGCTTGACGGGCATGTTAAAGACGGTGCCATTGGATACGATCTGTAACGAGC
AACGGCTTGGCGGATAGACG

Downstream 100 bases:

>100_bases
CTTCCGGCTCGCGGCCGATCTCTCCCTCGGCTCGCTTGCCATGGGCACGCCCCCATCAGGATGATCAGGCATCAAGGAAC
CGCTGGCGACCGTCAAAGTT

Product: two-component response regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MAAPQHDAHLLVVDDDPRIRQMLTRYFEDEGYTVSSAADGTEMRVRLRQQNFDAVLLDLVLPGGTDGLDLAREIRAQSDV
PIMMLTGRDDVVDRIVGLEVGADDYIAKPFHLREVHARLKSILRRRQPPARNPEAAGEEIIGFEDWKLNLSRRQLLDPEG
TEIELTTGEFDMLTTFVRHAGRVLTRDVLMDLTRGRNLEAFDRTIDAQIVRLRRKIETDPKKPQFIKAVRGVGYVFTARL
D

Sequences:

>Translated_241_residues
MAAPQHDAHLLVVDDDPRIRQMLTRYFEDEGYTVSSAADGTEMRVRLRQQNFDAVLLDLVLPGGTDGLDLAREIRAQSDV
PIMMLTGRDDVVDRIVGLEVGADDYIAKPFHLREVHARLKSILRRRQPPARNPEAAGEEIIGFEDWKLNLSRRQLLDPEG
TEIELTTGEFDMLTTFVRHAGRVLTRDVLMDLTRGRNLEAFDRTIDAQIVRLRRKIETDPKKPQFIKAVRGVGYVFTARL
D
>Mature_240_residues
AAPQHDAHLLVVDDDPRIRQMLTRYFEDEGYTVSSAADGTEMRVRLRQQNFDAVLLDLVLPGGTDGLDLAREIRAQSDVP
IMMLTGRDDVVDRIVGLEVGADDYIAKPFHLREVHARLKSILRRRQPPARNPEAAGEEIIGFEDWKLNLSRRQLLDPEGT
EIELTTGEFDMLTTFVRHAGRVLTRDVLMDLTRGRNLEAFDRTIDAQIVRLRRKIETDPKKPQFIKAVRGVGYVFTARLD

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=45.7264957264957, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=39.7435897435897, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=39.3162393162393, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=39.3939393939394, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=35.4700854700855, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.2105263157895, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=35.6521739130435, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=35.6223175965665, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=30.5676855895196, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=32.8947368421053, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.2173913043478, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.4561403508772, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=34.070796460177, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=30.0847457627119, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790299, Length=139, Percent_Identity=33.0935251798561, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=131, Percent_Identity=32.0610687022901, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27459; Mature: 27328

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPQHDAHLLVVDDDPRIRQMLTRYFEDEGYTVSSAADGTEMRVRLRQQNFDAVLLDLV
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEE
LPGGTDGLDLAREIRAQSDVPIMMLTGRDDVVDRIVGLEVGADDYIAKPFHLREVHARLK
CCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCEECCCCHHCCCHHHHHHHHHHH
SILRRRQPPARNPEAAGEEIIGFEDWKLNLSRRQLLDPEGTEIELTTGEFDMLTTFVRHA
HHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHCCCCCCCEEEEECCCHHHHHHHHHHH
GRVLTRDVLMDLTRGRNLEAFDRTIDAQIVRLRRKIETDPKKPQFIKAVRGVGYVFTARL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEC
D
C
>Mature Secondary Structure 
AAPQHDAHLLVVDDDPRIRQMLTRYFEDEGYTVSSAADGTEMRVRLRQQNFDAVLLDLV
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEE
LPGGTDGLDLAREIRAQSDVPIMMLTGRDDVVDRIVGLEVGADDYIAKPFHLREVHARLK
CCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCEECCCCHHCCCHHHHHHHHHHH
SILRRRQPPARNPEAAGEEIIGFEDWKLNLSRRQLLDPEGTEIELTTGEFDMLTTFVRHA
HHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHCCCCCCCEEEEECCCHHHHHHHHHHH
GRVLTRDVLMDLTRGRNLEAFDRTIDAQIVRLRRKIETDPKKPQFIKAVRGVGYVFTARL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]