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The map label for this gene is yeaO [H]

Identifier: 86361149

GI number: 86361149

Start: 474065

End: 474412

Strand: Direct

Name: yeaO [H]

Synonym: RHE_PF00419

Alternate gene names: 86361149

Gene position: 474065-474412 (Clockwise)

Preceding gene: 86361148

Following gene: 86361150

Centisome position: 73.78

GC content: 60.63

Gene sequence:

>348_bases
ATGGCCTTGCACATCAAACGAGTCTACGAGCCAAAAGAAGACCGGGACGGCACGCGTGTTCTGGTCGACAGGTTGTGGCC
GCGCGGCTTGAAGAAGCAGGAGGCGGCCGTCGATGTCTGGTTGAAAGAGATCGCGCCCAGCCCGGCGCTGCGCCGATGGT
TCGGCCACGACCCCGCCAAATGGAGCGAGTTCCAGCGCCGCTATCGCGACGAGCTCAAAAAGAACTCGTCAGCTGTGGAG
GAACTCGGACGCCGGATCGGGGAATCGGACGTCACACTTCTCTATGCGGCAAAAGATCCAGACCACAACCATGCGATCGT
GCTCCAGCGCTTCATCGGCGACAACTGA

Upstream 100 bases:

>100_bases
AGGCAGCGCAGTGTGACTAATTGGCAACCATCGGCCATGAGTGGAACCAAATCCTGCATCTGCGTATTCGCTCGGAATTA
CCTTTACAGCGGATGAGCAA

Downstream 100 bases:

>100_bases
AGCGGCCCGACAACCACCTCCCGCTGCGAAGATTTCCGGGAACCTTTTCGATCGATCTGCATCCAATGATCGCTTCCATC
CGACATAAGGAGACAGATCA

Product: hypothetical protein

Products: S-adenosyl-L-homocysteine; precorrin-1; Precorrin 2

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 114

Protein sequence:

>115_residues
MALHIKRVYEPKEDRDGTRVLVDRLWPRGLKKQEAAVDVWLKEIAPSPALRRWFGHDPAKWSEFQRRYRDELKKNSSAVE
ELGRRIGESDVTLLYAAKDPDHNHAIVLQRFIGDN

Sequences:

>Translated_115_residues
MALHIKRVYEPKEDRDGTRVLVDRLWPRGLKKQEAAVDVWLKEIAPSPALRRWFGHDPAKWSEFQRRYRDELKKNSSAVE
ELGRRIGESDVTLLYAAKDPDHNHAIVLQRFIGDN
>Mature_114_residues
ALHIKRVYEPKEDRDGTRVLVDRLWPRGLKKQEAAVDVWLKEIAPSPALRRWFGHDPAKWSEFQRRYRDELKKNSSAVEE
LGRRIGESDVTLLYAAKDPDHNHAIVLQRFIGDN

Specific function: Unknown

COG id: COG3189

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv3073c [H]

Homologues:

Organism=Escherichia coli, GI87081976, Length=108, Percent_Identity=44.4444444444444, Blast_Score=97, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007438 [H]

Pfam domain/function: PF04343 DUF488 [H]

EC number: 2.1.1.107

Molecular weight: Translated: 13474; Mature: 13343

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHIKRVYEPKEDRDGTRVLVDRLWPRGLKKQEAAVDVWLKEIAPSPALRRWFGHDPAK
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
WSEFQRRYRDELKKNSSAVEELGRRIGESDVTLLYAAKDPDHNHAIVLQRFIGDN
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
ALHIKRVYEPKEDRDGTRVLVDRLWPRGLKKQEAAVDVWLKEIAPSPALRRWFGHDPAK
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
WSEFQRRYRDELKKNSSAVEELGRRIGESDVTLLYAAKDPDHNHAIVLQRFIGDN
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; uroporphyrin III; precorrin-1

Specific reaction: (1) S-adenosyl-L-methionine + uroporphyrin III = S-adenosyl-L-homocysteine + precorrin-1; (2) S-adenosyl-L-methionine + precorrin-1 = S-adenosyl-L-homocysteine + precorrin-2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]