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The map label for this gene is gsiC [H]

Identifier: 86361082

GI number: 86361082

Start: 394959

End: 395909

Strand: Direct

Name: gsiC [H]

Synonym: RHE_PF00352

Alternate gene names: 86361082

Gene position: 394959-395909 (Clockwise)

Preceding gene: 86361081

Following gene: 86361083

Centisome position: 61.47

GC content: 57.31

Gene sequence:

>951_bases
ATGAACAATCCGATCCTGTCCCTTATAGCAAGCAGGCTGCTGATCGCAGTCGTCACGCTGATTATTGTATCCTTCGCGGT
GTTCTTCGCCACGACCATGCTTCCGGGCGATACGGCGTCCATCCTGCTCGGGCAGGCGGCAACGCCGGAGGCCGTCGAGG
GACTGCGCAAGGCAATGCATCTCGATCAGCCGGCTTTTCTCCGCTTCGTCTACTGGATGATCGGGCTGTTGTCGGGCGAC
CTCGGCACGTCCTACGCTAACGATATGCCAATCGCTGACCTCATCGGCGGCCGCTTTGCCAACTCGATGAAGCTGGCGGG
TATCACCGCCTTGTTTGCGGTGCCGATCGCGCTGACACTAGGCACCACAGCAGCCATGATGCGAGGATCGCTCTATGACC
GTGCAGTCACCGTGCTTACGATTGGCGTAATATCGGTGCCTGAATTCATGATCGCGACGTCGGCCGTCCTGTTCTTTGCG
GTCTATCTGCAATGGCTTCCGGCAATCTCCCTGACCAATGAAGCGAAAACCTTTACCGATATGCTACGCGTCTATGCGAT
GCCGGTGATCACACTGACCTTCGGCGTATCGGCGCAGATGATCCGAATGACGCGGGCTGCCGTGATTGAAACGCTGAACA
CGCCCTATGCCGAAATGGCGTTGCTGAAAGGCGCCTCACGCAGTCGCATCGTTTTGAAGCATGCATTGCCGAATGCACTC
GGCCCGATCGTCAACGCAGTTGCGCTCTCGCTTTCTTATCTGCTCGGCGGCGTCATCATCGTCGAAACGATCTTCAACTA
TCCCGGAATTGCCAAGCTCATGGTCGATGCGGTCGCAACGCGAGACCTGCCTCTTGTCCAGACCTGCGCGATGGTCTTCT
GCGTCGGCTACCTCATCCTCATCACGCTTGCCGACATTGTTGCCATTCTTTCCAATCCGAGGCTGCGATGA

Upstream 100 bases:

>100_bases
TGGAATCCTGACGAGGCACCTGGCCGGGAACAGGATTGTTCCCGGTCATCCTCCCCTTTCGTGATAAGCTGTCGGACTTC
GGCCGACGGGGAGCATGAAG

Downstream 100 bases:

>100_bases
CATCCCATATCGAACAACGGCCCGCCGTGGCGCGCCGGCTCAGCTACCGCTTCAATCTCGTCGGGCTCCTGGGGCTTGCC
GTGATCCTGTTCTGGGCCTT

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNNPILSLIASRLLIAVVTLIIVSFAVFFATTMLPGDTASILLGQAATPEAVEGLRKAMHLDQPAFLRFVYWMIGLLSGD
LGTSYANDMPIADLIGGRFANSMKLAGITALFAVPIALTLGTTAAMMRGSLYDRAVTVLTIGVISVPEFMIATSAVLFFA
VYLQWLPAISLTNEAKTFTDMLRVYAMPVITLTFGVSAQMIRMTRAAVIETLNTPYAEMALLKGASRSRIVLKHALPNAL
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMVDAVATRDLPLVQTCAMVFCVGYLILITLADIVAILSNPRLR

Sequences:

>Translated_316_residues
MNNPILSLIASRLLIAVVTLIIVSFAVFFATTMLPGDTASILLGQAATPEAVEGLRKAMHLDQPAFLRFVYWMIGLLSGD
LGTSYANDMPIADLIGGRFANSMKLAGITALFAVPIALTLGTTAAMMRGSLYDRAVTVLTIGVISVPEFMIATSAVLFFA
VYLQWLPAISLTNEAKTFTDMLRVYAMPVITLTFGVSAQMIRMTRAAVIETLNTPYAEMALLKGASRSRIVLKHALPNAL
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMVDAVATRDLPLVQTCAMVFCVGYLILITLADIVAILSNPRLR
>Mature_316_residues
MNNPILSLIASRLLIAVVTLIIVSFAVFFATTMLPGDTASILLGQAATPEAVEGLRKAMHLDQPAFLRFVYWMIGLLSGD
LGTSYANDMPIADLIGGRFANSMKLAGITALFAVPIALTLGTTAAMMRGSLYDRAVTVLTIGVISVPEFMIATSAVLFFA
VYLQWLPAISLTNEAKTFTDMLRVYAMPVITLTFGVSAQMIRMTRAAVIETLNTPYAEMALLKGASRSRIVLKHALPNAL
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMVDAVATRDLPLVQTCAMVFCVGYLILITLADIVAILSNPRLR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=312, Percent_Identity=34.2948717948718, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=27.9761904761905, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789888, Length=315, Percent_Identity=27.6190476190476, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=28.0254777070064, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787761, Length=307, Percent_Identity=29.6416938110749, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=27.8810408921933, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788504, Length=282, Percent_Identity=23.758865248227, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33862; Mature: 33862

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPILSLIASRLLIAVVTLIIVSFAVFFATTMLPGDTASILLGQAATPEAVEGLRKAMH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHC
LDQPAFLRFVYWMIGLLSGDLGTSYANDMPIADLIGGRFANSMKLAGITALFAVPIALTL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GTTAAMMRGSLYDRAVTVLTIGVISVPEFMIATSAVLFFAVYLQWLPAISLTNEAKTFTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHH
MLRVYAMPVITLTFGVSAQMIRMTRAAVIETLNTPYAEMALLKGASRSRIVLKHALPNAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCHHH
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMVDAVATRDLPLVQTCAMVFCVGYLIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ITLADIVAILSNPRLR
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNNPILSLIASRLLIAVVTLIIVSFAVFFATTMLPGDTASILLGQAATPEAVEGLRKAMH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHC
LDQPAFLRFVYWMIGLLSGDLGTSYANDMPIADLIGGRFANSMKLAGITALFAVPIALTL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GTTAAMMRGSLYDRAVTVLTIGVISVPEFMIATSAVLFFAVYLQWLPAISLTNEAKTFTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHH
MLRVYAMPVITLTFGVSAQMIRMTRAAVIETLNTPYAEMALLKGASRSRIVLKHALPNAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCHHH
GPIVNAVALSLSYLLGGVIIVETIFNYPGIAKLMVDAVATRDLPLVQTCAMVFCVGYLIL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ITLADIVAILSNPRLR
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]