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The map label for this gene is trxBf

Identifier: 86360868

GI number: 86360868

Start: 143910

End: 144815

Strand: Direct

Name: trxBf

Synonym: RHE_PF00137

Alternate gene names: 86360868

Gene position: 143910-144815 (Clockwise)

Preceding gene: 86360866

Following gene: 86360869

Centisome position: 22.4

GC content: 58.83

Gene sequence:

>906_bases
ATGCGCGATTGCATTATCATCGGAGGTGGACCTGCTGGCTTGACTGCGGCCATTTATCTTGCGCGCTATCACCTCTCAAC
AACCGTATTCGATGACCATAGCAGTCGTGCCGCCACCATTCCGATTTCCCATAACCTCGCAGGGTTCCCGGAGGGCATCA
GCGGAAGGGAGCTTCTCGCCAGGATGCGCACACAGCTTCAAAGGTACAAAGTTCAGATCCTGGCTGAGGGCGTTAGCCAG
CTTCGGAAGGAGCAGGTCGGCTTTCGAGTTCTCTCCAACAGCGGCAGCATGCGGGCCCGAACAGTCCTTCTCGCCACCGG
TGTCACCGACCGCAAGCCACCGATATTGGCCGAACGTCATGACGAGGCTGTTGCAGGCGGCCTTATCCGCTACTGCCCTG
TCTGTGACGGGTTCGAGGTGACCGACAAGCGTGTGGCTGTTATCGGTTGCGGATCGAGAGCGTTTGCGGAGGCGCTGTTC
CTGCGGAGTTATACGACACACGTGACCATCATCACACCGCAGGAGGAACACGAGCTCTCGGAGATTGAGGTCGATCGGCT
GCGGGACTTACAGATCGGCCTCCAGAAAGGTCCGGTAAAGTCCATCGACCCCGGGCGCGATGCAATCAGAGTCGCGACAG
CTTCCGGTATCGGCGAGTTTTCGTCTATATACCCGGCGCTTGGATCGGACGCTCGGTCGAAACTGGCAGCTGTGGCCGGT
GCAGAATTGTCGGAGAACGGCTGCGTCATCGTCGACAGTCACCAAAGGTCAACCCTACCTGGCCTGTATGCAGCTGGAGA
TGTGGTCGTTGGCTTGGATCAGATCGGGACCGCGATGGGCCAGGCGGGCATAGCGGCCACCGCGATCCGAAATGATTTGA
ACGAGGCTAGACCTCTAGCGCGCTAA

Upstream 100 bases:

>100_bases
ACCGCCCGCGAGCAGCTGTTGGGCGTGCCCAGGGAAATCAGAATGCTCCCCGCTAAGTGGCGCCTTACGACATCTTAAGC
GGCGACGGTCTGGAGACACG

Downstream 100 bases:

>100_bases
AGGATGCCGTCGCTGGGCCCCACCCCGCATTTCCGGAAAAGCGTGTGGACCGGGTGAGCCTGAGCCTTGCTCTACGTATT
GCTCAGTGCGCAGCAACCTT

Product: thioredoxin reductase (NADPH) protein

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MRDCIIIGGGPAGLTAAIYLARYHLSTTVFDDHSSRAATIPISHNLAGFPEGISGRELLARMRTQLQRYKVQILAEGVSQ
LRKEQVGFRVLSNSGSMRARTVLLATGVTDRKPPILAERHDEAVAGGLIRYCPVCDGFEVTDKRVAVIGCGSRAFAEALF
LRSYTTHVTIITPQEEHELSEIEVDRLRDLQIGLQKGPVKSIDPGRDAIRVATASGIGEFSSIYPALGSDARSKLAAVAG
AELSENGCVIVDSHQRSTLPGLYAAGDVVVGLDQIGTAMGQAGIAATAIRNDLNEARPLAR

Sequences:

>Translated_301_residues
MRDCIIIGGGPAGLTAAIYLARYHLSTTVFDDHSSRAATIPISHNLAGFPEGISGRELLARMRTQLQRYKVQILAEGVSQ
LRKEQVGFRVLSNSGSMRARTVLLATGVTDRKPPILAERHDEAVAGGLIRYCPVCDGFEVTDKRVAVIGCGSRAFAEALF
LRSYTTHVTIITPQEEHELSEIEVDRLRDLQIGLQKGPVKSIDPGRDAIRVATASGIGEFSSIYPALGSDARSKLAAVAG
AELSENGCVIVDSHQRSTLPGLYAAGDVVVGLDQIGTAMGQAGIAATAIRNDLNEARPLAR
>Mature_301_residues
MRDCIIIGGGPAGLTAAIYLARYHLSTTVFDDHSSRAATIPISHNLAGFPEGISGRELLARMRTQLQRYKVQILAEGVSQ
LRKEQVGFRVLSNSGSMRARTVLLATGVTDRKPPILAERHDEAVAGGLIRYCPVCDGFEVTDKRVAVIGCGSRAFAEALF
LRSYTTHVTIITPQEEHELSEIEVDRLRDLQIGLQKGPVKSIDPGRDAIRVATASGIGEFSSIYPALGSDARSKLAAVAG
AELSENGCVIVDSHQRSTLPGLYAAGDVVVGLDQIGTAMGQAGIAATAIRNDLNEARPLAR

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=285, Percent_Identity=27.3684210526316, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081763, Length=249, Percent_Identity=26.9076305220884, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320560, Length=287, Percent_Identity=28.2229965156794, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321898, Length=285, Percent_Identity=28.4210526315789, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 32101; Mature: 32101

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDCIIIGGGPAGLTAAIYLARYHLSTTVFDDHSSRAATIPISHNLAGFPEGISGRELLA
CCCEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHH
RMRTQLQRYKVQILAEGVSQLRKEQVGFRVLSNSGSMRARTVLLATGVTDRKPPILAERH
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCC
DEAVAGGLIRYCPVCDGFEVTDKRVAVIGCGSRAFAEALFLRSYTTHVTIITPQEEHELS
CHHHHCCHHHCCCCCCCCEECCCEEEEEECCCHHHHHHHHHHHHCCEEEEECCCHHHHHH
EIEVDRLRDLQIGLQKGPVKSIDPGRDAIRVATASGIGEFSSIYPALGSDARSKLAAVAG
HHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHC
AELSENGCVIVDSHQRSTLPGLYAAGDVVVGLDQIGTAMGQAGIAATAIRNDLNEARPLA
CCCCCCCEEEEECCCCCCCCCEEECCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
R
C
>Mature Secondary Structure
MRDCIIIGGGPAGLTAAIYLARYHLSTTVFDDHSSRAATIPISHNLAGFPEGISGRELLA
CCCEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHH
RMRTQLQRYKVQILAEGVSQLRKEQVGFRVLSNSGSMRARTVLLATGVTDRKPPILAERH
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCC
DEAVAGGLIRYCPVCDGFEVTDKRVAVIGCGSRAFAEALFLRSYTTHVTIITPQEEHELS
CHHHHCCHHHCCCCCCCCEECCCEEEEEECCCHHHHHHHHHHHHCCEEEEECCCHHHHHH
EIEVDRLRDLQIGLQKGPVKSIDPGRDAIRVATASGIGEFSSIYPALGSDARSKLAAVAG
HHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHC
AELSENGCVIVDSHQRSTLPGLYAAGDVVVGLDQIGTAMGQAGIAATAIRNDLNEARPLA
CCCCCCCEEEEECCCCCCCCCEEECCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]