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The map label for this gene is 86360812

Identifier: 86360812

GI number: 86360812

Start: 82176

End: 83849

Strand: Direct

Name: 86360812

Synonym: RHE_PF00079

Alternate gene names: NA

Gene position: 82176-83849 (Clockwise)

Preceding gene: 86360810

Following gene: 86360813

Centisome position: 12.79

GC content: 61.59

Gene sequence:

>1674_bases
ATGAGACTCAAACTGGTTGCAGTTGCGGTCGCGGCGCTGGCGCCGGTGGTTGCAATGCTCTTCTACAACGAAGTCGCGCT
CCGCCACCAGCGCAACGAGGAGGTGCGCACCTCGGCTGCACAGGCGGCGAGGCAAGCCTCGTCGGAAGTCGAACGGATCA
TAGAGGGCCTGCACGCCCTTCTCGTCTCCGTGTCCTCGATGCCGTCCGTCAGGCACCTCGACGTCCAGGCTTGCAACGAC
GCGCTGAAATCGGTTGCCGAAAACATTCCCAACATCCGCACCATCTTCGTCGCCGGGCTCGATGGGCGGCCGATCTGCGG
AAGCATGGCTTTCCCGAAGGGCGTGGTCTTTTCCGACCGCGATTATTTCCAGCAGACTTTGGAGACCAAAGACTTTTCCG
TCGGTACCTATACGCAGAGCCGCCTTTCCGACCGCCCGGTGCTGCCGCTCGCGATACCCCTGATGGAAGGCGATACCATC
AAGGCCATCATCGTCAGCGGAATCCGGCTTGACTGGCTGCAGAACCGCATCACCGAGCGCGGGGTTGCTCCCGGCAATGA
GGTGACCATCGCCGATGGCAAGGGAACCATCGTCGCGCACGTCCCCTCTCCCGATCAGTTCGTCGGTACGATCTTGCCCG
AGGAATACCAGCGGCTGATCCACGCCGAACAGCCTGATGTAATCGAGATCACCAGCCAGGACGGAACAGCGCGCATCCTC
GGTTACCGCCCGATAGCCTTGCCTTCCAGTCCCCTCTATGTCAGCGCCGGCTTTTCGAAAACGGAGGTCTTCGCGCCGAT
CGATCGGGCGACGCTGATGAATACGCTCGCCATCATCGGCGGTGCGCTTTTCGCCTTCGTCGCCGCGATCTTTATCGGCA
ACCGCTTCATCCTGATGCCGATCTCCAGGATCGCAGATGTGATGGAAAGTTGGCGCAGCGGTCAGACGACAGCGCGGACC
GGCATGAAGGGACCGGACGAGCTGGGGCTCGTCGGCGCAACCTTCGATCGGCTGCTCGACGAACTCGAAGAGCGCAGGCG
CCAAAATCAGAAGGCGGAGGAGGAGCGGAGCCTGCTCGTCGGCGAGCTGGCGCATCGCGTCAAGAATGGCTTCACGCTCG
TGCAGGCGATTGCCAGACAAACCTTCTCGCGGTCCGATCCGGAGAGATACAGTTCCTTTGCCGAGAGGCTCGCAGCCCTC
GCCGGTACCTATGACCTCATCCTGTCTCGGGAGGGGTTGGCTTCACCCATTCGGGATATCCTCTCCGCAGCGCTGCGGGC
GCATGTCGCCTCGCAAGCCGATCGCATTCGTCTCGATGGGCCGGACGTCGTTCTTCCGGCGGACACCGCCCTGCCGCTCT
CGCTCGTGATTCATGAGCTGGCGACCAACGCAACCAAGTATGGAAGCCTCGGCAGCGAAAATGGAACAGTCACCATCGAA
TGGAAACACGACGATGGACGTGTCCTCCTTCTGTGGACGGAAGCCGGTGGACCGCCGGTCTCGACGCCGACGAAAAAGGG
CTTCGGCTCGGTGCTCATCGAACGTGCCTTCCCGTCGAAGGCGCAGGCGCGATTCCGCGTGGACTACCGCACCGAAGGCC
TCATCTTCGAAGTAATATTTTCGATCGGGGAACCGGTTGCCAAAGGCGAAGTTGACCCTCTGAGCCGGACGTAA

Upstream 100 bases:

>100_bases
TCGGGATTCGTATGTTGATATTTTGTAAACAAGATTGCGCGCGCGGTCTGGGCCGGATCGTCTCGATCATGCTACCAACC
CTTTTCCGAGAGGGGACAGT

Downstream 100 bases:

>100_bases
AGCATACGAGCTAGAGATGAAAACCAAGGTTGTCGTGGTCGAGGACGAGGCTCTGCTGCTGATGACGGCGGTCGCCATCG
TCGAGGAGGCAGGCTTTGAA

Product: putative two-component sensor histidine kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MRLKLVAVAVAALAPVVAMLFYNEVALRHQRNEEVRTSAAQAARQASSEVERIIEGLHALLVSVSSMPSVRHLDVQACND
ALKSVAENIPNIRTIFVAGLDGRPICGSMAFPKGVVFSDRDYFQQTLETKDFSVGTYTQSRLSDRPVLPLAIPLMEGDTI
KAIIVSGIRLDWLQNRITERGVAPGNEVTIADGKGTIVAHVPSPDQFVGTILPEEYQRLIHAEQPDVIEITSQDGTARIL
GYRPIALPSSPLYVSAGFSKTEVFAPIDRATLMNTLAIIGGALFAFVAAIFIGNRFILMPISRIADVMESWRSGQTTART
GMKGPDELGLVGATFDRLLDELEERRRQNQKAEEERSLLVGELAHRVKNGFTLVQAIARQTFSRSDPERYSSFAERLAAL
AGTYDLILSREGLASPIRDILSAALRAHVASQADRIRLDGPDVVLPADTALPLSLVIHELATNATKYGSLGSENGTVTIE
WKHDDGRVLLLWTEAGGPPVSTPTKKGFGSVLIERAFPSKAQARFRVDYRTEGLIFEVIFSIGEPVAKGEVDPLSRT

Sequences:

>Translated_557_residues
MRLKLVAVAVAALAPVVAMLFYNEVALRHQRNEEVRTSAAQAARQASSEVERIIEGLHALLVSVSSMPSVRHLDVQACND
ALKSVAENIPNIRTIFVAGLDGRPICGSMAFPKGVVFSDRDYFQQTLETKDFSVGTYTQSRLSDRPVLPLAIPLMEGDTI
KAIIVSGIRLDWLQNRITERGVAPGNEVTIADGKGTIVAHVPSPDQFVGTILPEEYQRLIHAEQPDVIEITSQDGTARIL
GYRPIALPSSPLYVSAGFSKTEVFAPIDRATLMNTLAIIGGALFAFVAAIFIGNRFILMPISRIADVMESWRSGQTTART
GMKGPDELGLVGATFDRLLDELEERRRQNQKAEEERSLLVGELAHRVKNGFTLVQAIARQTFSRSDPERYSSFAERLAAL
AGTYDLILSREGLASPIRDILSAALRAHVASQADRIRLDGPDVVLPADTALPLSLVIHELATNATKYGSLGSENGTVTIE
WKHDDGRVLLLWTEAGGPPVSTPTKKGFGSVLIERAFPSKAQARFRVDYRTEGLIFEVIFSIGEPVAKGEVDPLSRT
>Mature_557_residues
MRLKLVAVAVAALAPVVAMLFYNEVALRHQRNEEVRTSAAQAARQASSEVERIIEGLHALLVSVSSMPSVRHLDVQACND
ALKSVAENIPNIRTIFVAGLDGRPICGSMAFPKGVVFSDRDYFQQTLETKDFSVGTYTQSRLSDRPVLPLAIPLMEGDTI
KAIIVSGIRLDWLQNRITERGVAPGNEVTIADGKGTIVAHVPSPDQFVGTILPEEYQRLIHAEQPDVIEITSQDGTARIL
GYRPIALPSSPLYVSAGFSKTEVFAPIDRATLMNTLAIIGGALFAFVAAIFIGNRFILMPISRIADVMESWRSGQTTART
GMKGPDELGLVGATFDRLLDELEERRRQNQKAEEERSLLVGELAHRVKNGFTLVQAIARQTFSRSDPERYSSFAERLAAL
AGTYDLILSREGLASPIRDILSAALRAHVASQADRIRLDGPDVVLPADTALPLSLVIHELATNATKYGSLGSENGTVTIE
WKHDDGRVLLLWTEAGGPPVSTPTKKGFGSVLIERAFPSKAQARFRVDYRTEGLIFEVIFSIGEPVAKGEVDPLSRT

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60701; Mature: 60701

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKLVAVAVAALAPVVAMLFYNEVALRHQRNEEVRTSAAQAARQASSEVERIIEGLHAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVSVSSMPSVRHLDVQACNDALKSVAENIPNIRTIFVAGLDGRPICGSMAFPKGVVFSDR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEECCH
DYFQQTLETKDFSVGTYTQSRLSDRPVLPLAIPLMEGDTIKAIIVSGIRLDWLQNRITER
HHHHHHHCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCEEEHHHCCHHHHHHHHHHHHC
GVAPGNEVTIADGKGTIVAHVPSPDQFVGTILPEEYQRLIHAEQPDVIEITSQDGTARIL
CCCCCCEEEEECCCCEEEEECCCCHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCEEEE
GYRPIALPSSPLYVSAGFSKTEVFAPIDRATLMNTLAIIGGALFAFVAAIFIGNRFILMP
EECCCCCCCCCEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
ISRIADVMESWRSGQTTARTGMKGPDELGLVGATFDRLLDELEERRRQNQKAEEERSLLV
HHHHHHHHHHHHCCCCHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GELAHRVKNGFTLVQAIARQTFSRSDPERYSSFAERLAALAGTYDLILSREGLASPIRDI
HHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHH
LSAALRAHVASQADRIRLDGPDVVLPADTALPLSLVIHELATNATKYGSLGSENGTVTIE
HHHHHHHHHHHCCCEEEECCCCEEECCCCCCHHHHHHHHHHHCCHHCCCCCCCCCEEEEE
WKHDDGRVLLLWTEAGGPPVSTPTKKGFGSVLIERAFPSKAQARFRVDYRTEGLIFEVIF
EEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHH
SIGEPVAKGEVDPLSRT
HHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLKLVAVAVAALAPVVAMLFYNEVALRHQRNEEVRTSAAQAARQASSEVERIIEGLHAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVSVSSMPSVRHLDVQACNDALKSVAENIPNIRTIFVAGLDGRPICGSMAFPKGVVFSDR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCEECCH
DYFQQTLETKDFSVGTYTQSRLSDRPVLPLAIPLMEGDTIKAIIVSGIRLDWLQNRITER
HHHHHHHCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCEEEHHHCCHHHHHHHHHHHHC
GVAPGNEVTIADGKGTIVAHVPSPDQFVGTILPEEYQRLIHAEQPDVIEITSQDGTARIL
CCCCCCEEEEECCCCEEEEECCCCHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCEEEE
GYRPIALPSSPLYVSAGFSKTEVFAPIDRATLMNTLAIIGGALFAFVAAIFIGNRFILMP
EECCCCCCCCCEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
ISRIADVMESWRSGQTTARTGMKGPDELGLVGATFDRLLDELEERRRQNQKAEEERSLLV
HHHHHHHHHHHHCCCCHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GELAHRVKNGFTLVQAIARQTFSRSDPERYSSFAERLAALAGTYDLILSREGLASPIRDI
HHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHH
LSAALRAHVASQADRIRLDGPDVVLPADTALPLSLVIHELATNATKYGSLGSENGTVTIE
HHHHHHHHHHHCCCEEEECCCCEEECCCCCCHHHHHHHHHHHCCHHCCCCCCCCCEEEEE
WKHDDGRVLLLWTEAGGPPVSTPTKKGFGSVLIERAFPSKAQARFRVDYRTEGLIFEVIF
EEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHH
SIGEPVAKGEVDPLSRT
HHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA