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The map label for this gene is cscR

Identifier: 86360780

GI number: 86360780

Start: 48021

End: 48860

Strand: Direct

Name: cscR

Synonym: RHE_PF00046

Alternate gene names: 86360780

Gene position: 48021-48860 (Clockwise)

Preceding gene: 86360779

Following gene: 86360781

Centisome position: 7.47

GC content: 67.5

Gene sequence:

>840_bases
ATGCGGCAGGGCTGGATGCCGCTCGTCGGTCTCGTCGCCGACGATCTGATCACCTCGCCCTTCGCCACCGAGATCATCAG
GGGGCTCGACGGCGCCGTGCGCGCGGCCGACATGGCCGTGTTCGCCATGACGCTCGGCGGCCACCGGAGCATCGCCTCGA
TCCTCGACGAGATGCGCCGCTTTCGCCCGCGGGCGATTGCCTATGCCGCCATGTATCACAAGAGCGTCGACCTGCCGCCC
GAATTTGCCGATGCGGTCGGCGTGATGATCAACTGCCGGGACGCCAATGACCGCGTGACCTCGCTGGTGCCCGATGAATC
CGGGGCGGCGATCGAGATTACCAATTATCTCATCGATGCCGGCCGTCGCAACATCGCCTTCATCAACCTGCCCGGGCTGC
TCGCCGGCGAACTGCGGGAACTCGGGTTCCGGCAGGCGCTCGAGCACGCCGGCATCGACGGAGCCGGCGCCATCGTCCTG
CCTGCCGTCAGCAAGGCGATCTACAGCGACCGCGCCCACAGCCTTGTCTCCGCGCATGTGCAGGAGCTGATGATCGGTCC
CCGGCGCCCCGATGCCATCCTGTGCGGCAATGACCGGGTGGCCATGGAGGTCTATGCCGCGCTGCGCCGGGCAGGCGCGG
CCATTCCCGACGACGTCGCCGTTGCGAGTTTCGACAACCAGGTCGAGATCGCCTCGCGTCTCGATCCACCACTGACCACC
ATGGCGCTCCCCCATCGCGCCATGGGCCGCCAGGCCGCCCAAATCCTGCTTGCCGAAGACCGCGCCCCGGTCGGGGTGCA
GAAACTGCCGTTCCAGCTGGTGGAGCGGGCATCCGTATAA

Upstream 100 bases:

>100_bases
CTTGCATGGTGGTTCGGCGCGCATGTCTGAGGAAACCCGGCAGCGGATCAAGGAGATCGCCGAGGAGCTCGGCTATGTCA
CCAACTTCGCCGCGCGCAGC

Downstream 100 bases:

>100_bases
TTGAAATAGGCCCATTCAAATGGAGGAGGAATTCTAATGGGTAAACGTTTACTTTGGACTCTGGTCATGTCCTCGGCACT
GTCAGCCATAGGGGCGCAGG

Product: LacI family sucrose operon repressor

Products: NA

Alternate protein names: Csc operon regulatory protein [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRQGWMPLVGLVADDLITSPFATEIIRGLDGAVRAADMAVFAMTLGGHRSIASILDEMRRFRPRAIAYAAMYHKSVDLPP
EFADAVGVMINCRDANDRVTSLVPDESGAAIEITNYLIDAGRRNIAFINLPGLLAGELRELGFRQALEHAGIDGAGAIVL
PAVSKAIYSDRAHSLVSAHVQELMIGPRRPDAILCGNDRVAMEVYAALRRAGAAIPDDVAVASFDNQVEIASRLDPPLTT
MALPHRAMGRQAAQILLAEDRAPVGVQKLPFQLVERASV

Sequences:

>Translated_279_residues
MRQGWMPLVGLVADDLITSPFATEIIRGLDGAVRAADMAVFAMTLGGHRSIASILDEMRRFRPRAIAYAAMYHKSVDLPP
EFADAVGVMINCRDANDRVTSLVPDESGAAIEITNYLIDAGRRNIAFINLPGLLAGELRELGFRQALEHAGIDGAGAIVL
PAVSKAIYSDRAHSLVSAHVQELMIGPRRPDAILCGNDRVAMEVYAALRRAGAAIPDDVAVASFDNQVEIASRLDPPLTT
MALPHRAMGRQAAQILLAEDRAPVGVQKLPFQLVERASV
>Mature_279_residues
MRQGWMPLVGLVADDLITSPFATEIIRGLDGAVRAADMAVFAMTLGGHRSIASILDEMRRFRPRAIAYAAMYHKSVDLPP
EFADAVGVMINCRDANDRVTSLVPDESGAAIEITNYLIDAGRRNIAFINLPGLLAGELRELGFRQALEHAGIDGAGAIVL
PAVSKAIYSDRAHSLVSAHVQELMIGPRRPDAILCGNDRVAMEVYAALRRAGAAIPDDVAVASFDNQVEIASRLDPPLTT
MALPHRAMGRQAAQILLAEDRAPVGVQKLPFQLVERASV

Specific function: Repressor for the csc operon. Binds D-fructose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=269, Percent_Identity=27.8810408921933, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790369, Length=255, Percent_Identity=28.6274509803922, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787948, Length=171, Percent_Identity=32.1637426900585, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 29996; Mature: 29996

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQGWMPLVGLVADDLITSPFATEIIRGLDGAVRAADMAVFAMTLGGHRSIASILDEMRR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FRPRAIAYAAMYHKSVDLPPEFADAVGVMINCRDANDRVTSLVPDESGAAIEITNYLIDA
HCHHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCHHHEECCCCCCCEEEEHHHHHHC
GRRNIAFINLPGLLAGELRELGFRQALEHAGIDGAGAIVLPAVSKAIYSDRAHSLVSAHV
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QELMIGPRRPDAILCGNDRVAMEVYAALRRAGAAIPDDVAVASFDNQVEIASRLDPPLTT
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHCCCCHHH
MALPHRAMGRQAAQILLAEDRAPVGVQKLPFQLVERASV
HHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRQGWMPLVGLVADDLITSPFATEIIRGLDGAVRAADMAVFAMTLGGHRSIASILDEMRR
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FRPRAIAYAAMYHKSVDLPPEFADAVGVMINCRDANDRVTSLVPDESGAAIEITNYLIDA
HCHHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCHHHEECCCCCCCEEEEHHHHHHC
GRRNIAFINLPGLLAGELRELGFRQALEHAGIDGAGAIVLPAVSKAIYSDRAHSLVSAHV
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QELMIGPRRPDAILCGNDRVAMEVYAALRRAGAAIPDDVAVASFDNQVEIASRLDPPLTT
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHCCCCHHH
MALPHRAMGRQAAQILLAEDRAPVGVQKLPFQLVERASV
HHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA