Click here to switch to the map view.

The map label for this gene is fdhA [H]

Identifier: 85860856

GI number: 85860856

Start: 3017717

End: 3019768

Strand: Direct

Name: fdhA [H]

Synonym: SYN_01672

Alternate gene names: 85860856

Gene position: 3017717-3019768 (Clockwise)

Preceding gene: 85860854

Following gene: 85860857

Centisome position: 94.92

GC content: 61.31

Gene sequence:

>2052_bases
ATGCAATGCCATACGGTGTGCCGACTCTGTTCAGCCTGCTGCCCGGTCACGGTAACTGTGGAGGCCGGGAAAATGGTCCG
CGCGGCAAGAAAATCCTTTCTGCCTGAAGAGAAGCGTCTCTCCTGCCCCAAACTTGCCGCGGCTCCGGAAATTGTTTATT
CCCCGGCCCGTATACTCCGTCCCCTGATCAGATCCGGACCGGGCAACGGTTTTCACGAGGCCTCCTGGGATGAAGCGCTG
GGGCGGGTGGCGGAGCGGTTCAACTTCTTCAGGCGGACCGACGGCGCCCAGTCCATTGCCTGGCTGCGGGGCATGGCAGC
CGACTGGGGCGCGCCCTGGGATTACGCCTGCCGACTCATGAACGCCTTCGGCTCCCCCAACACAATCGGCAACGGTTCCG
TCTGCCATGTCGCCCGGGAGATGGCCCATGCCTTTACTTACGGCGCCATGACTCTTCCCCAGCCCCGGAATTCCCGATGC
ATCCTCATCTGGGGAAAAAACGACCGCAACACCGCTCCAGGCGTCTGCGAACAGATCCTTCATGCCCGATCCCATGGCGC
ACGGCTTATCGTTGTCGATCCGATCAGGACATCCTTCGCGCAGATGGCCGACATCTGGCTGCAGATCAAGCCGGGCCATG
ACGGCCCGCTGGCGATGGCCATGCTGAACGAGATCATCAACAACAATCTATACGACGCCGCATTCGTCGATCAATACGGT
ATTGGATTCGACGAGCTGCGAGCGGCTGTCGCGCACTTTTCTCCGGACCTGGTTGCCGCGGATCTCTGGCTCGATCCAGA
GGACATCCGCCGTGCAGCCCGGCTCTACGCCACAACCAGACCTGCCTGCATCATTGACGGCAACGGCCTGGACATGCAGC
TTTCGACCTTCCAGGCGACCCGGGCGGTCTGTATGCTCCGGGCCGTTACAGGAAATATCGACCGGGAAGGCGGGGACTTG
ATTCCCCAGCCGATCCCTCTGAAGAATATCCAACTCAAAGAGCGGCTTCCCAAAGACGTTCAACCGGTTACCGCAGCCTA
TCCCCTCTTCGACGCCTTCCACCCCACCTGGGGCCGCCACGCCCAGTCGTGTCTGATCGATGCCATTCTCGGGGAGCGAC
CCTATCCGATCCGGATGCTTGTCGTGCAGTCGGGAAATCCGGCGGTCACGATGACCGATGCAAAGCGGGTCCGGCGGGCG
CTTCAGAAACTGGACTTTCTCGTGGTGATCGATCTCTTCCGGAACCGGACGGCAGAGATGGCCGACGTCATCCTACCGGC
GGCAAGCTGCTTTGAGAAAACCCAGCTCAACCGCGCCTCGATGCGCAGCAGCCCCGTGGTCCTCCAGAATCAGGTCATCG
ACTGCCTGGGCGAGAGCCGACCGGACTGGCAGATCGTTTTCGAACTGGGACGCCGCCTGGGACTGGAAGCTGATTTTCCC
TGGGCGTCGGTGGAGGCGGCCATCGATGAACAGCTTTCCCCCTCTGGTCTGACGGTGGCCTTCCTGCGGGAAAATCCCGA
TGGTCTGTGGACCGAGCCAACGAAATTCGAAAAATACCGCAGCAAAGGGTTTGCCACGCCGTCCGGCAGGGTGGAGTTTC
ATTCAGACCGGCTTGCCCGGGCAGGGCATGCGCCGGTACCCTTTGCCGAGGGAACCTTTGAAGACCTGCCCGGTTCCGCA
GACGCATGCAATGCCGACGTCGTGATCGGGATAAGCGGCGAGAGGACGAACCGCTTCACCCACACCCAGTTCCTGCGCAT
CCCGTCCCTGGCACGTCAGGAACCGGAAGGCTTCGTGGATATTCATCCCCGGGATGCGGCGGCAAGGGGAATCAGCGACG
GGCAGGAAATCACGATCTCCAACGAACGGGGACAGGTGCGGATGAAGGCCCGGATCTCCGACGTCGTCCACCCCGGGTCG
ATCCGCATCGCCTGGGGGTGGGGAGAGATCGACCCGGATGCCAACGTCAACAATCTGACCGATGACAACCGGCGGGATCC
CATCACTGCTACACCGTCAAATCGCAGTTTTTTATGTCGCATCGAGACCTGA

Upstream 100 bases:

>100_bases
CTGCAACCATTACGAATCGATTCGAAGCTGCTTTGTCAAGGCAGCGCGCTGAGCGAGCAAGCCGATACACGCTTATCTTT
GAGAAAAAAGGAGGGACATC

Downstream 100 bases:

>100_bases
GGCCATGAACGGCGATGGTCATTCCTGTTCCAATGAGCGAAGACATCGATGCGGCCGGGAGGCAATGCAGGAGAACCGCG
CGGGAAGGTCGAGGAGTCGA

Product: molybdopterin dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MQCHTVCRLCSACCPVTVTVEAGKMVRAARKSFLPEEKRLSCPKLAAAPEIVYSPARILRPLIRSGPGNGFHEASWDEAL
GRVAERFNFFRRTDGAQSIAWLRGMAADWGAPWDYACRLMNAFGSPNTIGNGSVCHVAREMAHAFTYGAMTLPQPRNSRC
ILIWGKNDRNTAPGVCEQILHARSHGARLIVVDPIRTSFAQMADIWLQIKPGHDGPLAMAMLNEIINNNLYDAAFVDQYG
IGFDELRAAVAHFSPDLVAADLWLDPEDIRRAARLYATTRPACIIDGNGLDMQLSTFQATRAVCMLRAVTGNIDREGGDL
IPQPIPLKNIQLKERLPKDVQPVTAAYPLFDAFHPTWGRHAQSCLIDAILGERPYPIRMLVVQSGNPAVTMTDAKRVRRA
LQKLDFLVVIDLFRNRTAEMADVILPAASCFEKTQLNRASMRSSPVVLQNQVIDCLGESRPDWQIVFELGRRLGLEADFP
WASVEAAIDEQLSPSGLTVAFLRENPDGLWTEPTKFEKYRSKGFATPSGRVEFHSDRLARAGHAPVPFAEGTFEDLPGSA
DACNADVVIGISGERTNRFTHTQFLRIPSLARQEPEGFVDIHPRDAAARGISDGQEITISNERGQVRMKARISDVVHPGS
IRIAWGWGEIDPDANVNNLTDDNRRDPITATPSNRSFLCRIET

Sequences:

>Translated_683_residues
MQCHTVCRLCSACCPVTVTVEAGKMVRAARKSFLPEEKRLSCPKLAAAPEIVYSPARILRPLIRSGPGNGFHEASWDEAL
GRVAERFNFFRRTDGAQSIAWLRGMAADWGAPWDYACRLMNAFGSPNTIGNGSVCHVAREMAHAFTYGAMTLPQPRNSRC
ILIWGKNDRNTAPGVCEQILHARSHGARLIVVDPIRTSFAQMADIWLQIKPGHDGPLAMAMLNEIINNNLYDAAFVDQYG
IGFDELRAAVAHFSPDLVAADLWLDPEDIRRAARLYATTRPACIIDGNGLDMQLSTFQATRAVCMLRAVTGNIDREGGDL
IPQPIPLKNIQLKERLPKDVQPVTAAYPLFDAFHPTWGRHAQSCLIDAILGERPYPIRMLVVQSGNPAVTMTDAKRVRRA
LQKLDFLVVIDLFRNRTAEMADVILPAASCFEKTQLNRASMRSSPVVLQNQVIDCLGESRPDWQIVFELGRRLGLEADFP
WASVEAAIDEQLSPSGLTVAFLRENPDGLWTEPTKFEKYRSKGFATPSGRVEFHSDRLARAGHAPVPFAEGTFEDLPGSA
DACNADVVIGISGERTNRFTHTQFLRIPSLARQEPEGFVDIHPRDAAARGISDGQEITISNERGQVRMKARISDVVHPGS
IRIAWGWGEIDPDANVNNLTDDNRRDPITATPSNRSFLCRIET
>Mature_683_residues
MQCHTVCRLCSACCPVTVTVEAGKMVRAARKSFLPEEKRLSCPKLAAAPEIVYSPARILRPLIRSGPGNGFHEASWDEAL
GRVAERFNFFRRTDGAQSIAWLRGMAADWGAPWDYACRLMNAFGSPNTIGNGSVCHVAREMAHAFTYGAMTLPQPRNSRC
ILIWGKNDRNTAPGVCEQILHARSHGARLIVVDPIRTSFAQMADIWLQIKPGHDGPLAMAMLNEIINNNLYDAAFVDQYG
IGFDELRAAVAHFSPDLVAADLWLDPEDIRRAARLYATTRPACIIDGNGLDMQLSTFQATRAVCMLRAVTGNIDREGGDL
IPQPIPLKNIQLKERLPKDVQPVTAAYPLFDAFHPTWGRHAQSCLIDAILGERPYPIRMLVVQSGNPAVTMTDAKRVRRA
LQKLDFLVVIDLFRNRTAEMADVILPAASCFEKTQLNRASMRSSPVVLQNQVIDCLGESRPDWQIVFELGRRLGLEADFP
WASVEAAIDEQLSPSGLTVAFLRENPDGLWTEPTKFEKYRSKGFATPSGRVEFHSDRLARAGHAPVPFAEGTFEDLPGSA
DACNADVVIGISGERTNRFTHTQFLRIPSLARQEPEGFVDIHPRDAAARGISDGQEITISNERGQVRMKARISDVVHPGS
IRIAWGWGEIDPDANVNNLTDDNRRDPITATPSNRSFLCRIET

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=723, Percent_Identity=25.0345781466113, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87081797, Length=767, Percent_Identity=25.9452411994785, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI171474008, Length=711, Percent_Identity=25.3164556962025, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1787870, Length=715, Percent_Identity=26.2937062937063, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI3868719, Length=262, Percent_Identity=25.5725190839695, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 75594; Mature: 75594

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCHTVCRLCSACCPVTVTVEAGKMVRAARKSFLPEEKRLSCPKLAAAPEIVYSPARILR
CCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCHHHCCCCCHHCCCHHHCCCHHHHH
PLIRSGPGNGFHEASWDEALGRVAERFNFFRRTDGAQSIAWLRGMAADWGAPWDYACRLM
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
NAFGSPNTIGNGSVCHVAREMAHAFTYGAMTLPQPRNSRCILIWGKNDRNTAPGVCEQIL
HHCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEECCCCCCCCCHHHHHHH
HARSHGARLIVVDPIRTSFAQMADIWLQIKPGHDGPLAMAMLNEIINNNLYDAAFVDQYG
HHHCCCCEEEEECCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHC
IGFDELRAAVAHFSPDLVAADLWLDPEDIRRAARLYATTRPACIIDGNGLDMQLSTFQAT
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEHHHHHH
RAVCMLRAVTGNIDREGGDLIPQPIPLKNIQLKERLPKDVQPVTAAYPLFDAFHPTWGRH
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHH
AQSCLIDAILGERPYPIRMLVVQSGNPAVTMTDAKRVRRALQKLDFLVVIDLFRNRTAEM
HHHHHHHHHHCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHCCHHHH
ADVILPAASCFEKTQLNRASMRSSPVVLQNQVIDCLGESRPDWQIVFELGRRLGLEADFP
HHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
WASVEAAIDEQLSPSGLTVAFLRENPDGLWTEPTKFEKYRSKGFATPSGRVEFHSDRLAR
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCEEECCHHHHH
AGHAPVPFAEGTFEDLPGSADACNADVVIGISGERTNRFTHTQFLRIPSLARQEPEGFVD
CCCCCCCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCHHHHCCCCCEEE
IHPRDAAARGISDGQEITISNERGQVRMKARISDVVHPGSIRIAWGWGEIDPDANVNNLT
ECCCHHHHCCCCCCCEEEEECCCCCEEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
DDNRRDPITATPSNRSFLCRIET
CCCCCCCEEECCCCCEEEEEECC
>Mature Secondary Structure
MQCHTVCRLCSACCPVTVTVEAGKMVRAARKSFLPEEKRLSCPKLAAAPEIVYSPARILR
CCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCHHHCCCCCHHCCCHHHCCCHHHHH
PLIRSGPGNGFHEASWDEALGRVAERFNFFRRTDGAQSIAWLRGMAADWGAPWDYACRLM
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
NAFGSPNTIGNGSVCHVAREMAHAFTYGAMTLPQPRNSRCILIWGKNDRNTAPGVCEQIL
HHCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEECCCCCCCCCHHHHHHH
HARSHGARLIVVDPIRTSFAQMADIWLQIKPGHDGPLAMAMLNEIINNNLYDAAFVDQYG
HHHCCCCEEEEECCHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHC
IGFDELRAAVAHFSPDLVAADLWLDPEDIRRAARLYATTRPACIIDGNGLDMQLSTFQAT
CCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEHHHHHH
RAVCMLRAVTGNIDREGGDLIPQPIPLKNIQLKERLPKDVQPVTAAYPLFDAFHPTWGRH
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHH
AQSCLIDAILGERPYPIRMLVVQSGNPAVTMTDAKRVRRALQKLDFLVVIDLFRNRTAEM
HHHHHHHHHHCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHCCHHHH
ADVILPAASCFEKTQLNRASMRSSPVVLQNQVIDCLGESRPDWQIVFELGRRLGLEADFP
HHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
WASVEAAIDEQLSPSGLTVAFLRENPDGLWTEPTKFEKYRSKGFATPSGRVEFHSDRLAR
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCEEECCHHHHH
AGHAPVPFAEGTFEDLPGSADACNADVVIGISGERTNRFTHTQFLRIPSLARQEPEGFVD
CCCCCCCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCHHHHCCCCCEEE
IHPRDAAARGISDGQEITISNERGQVRMKARISDVVHPGSIRIAWGWGEIDPDANVNNLT
ECCCHHHHCCCCCCCEEEEECCCCCEEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
DDNRRDPITATPSNRSFLCRIET
CCCCCCCEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]