| Definition | Syntrophus aciditrophicus SB chromosome, complete genome. |
|---|---|
| Accession | NC_007759 |
| Length | 3,179,300 |
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The map label for this gene is fabG [H]
Identifier: 85860848
GI number: 85860848
Start: 3011897
End: 3012652
Strand: Direct
Name: fabG [H]
Synonym: SYN_01680
Alternate gene names: 85860848
Gene position: 3011897-3012652 (Clockwise)
Preceding gene: 85860845
Following gene: 85860849
Centisome position: 94.73
GC content: 48.54
Gene sequence:
>756_bases ATGGGAAAGTTAGATGGTAAGGTAGCTGTGGTAACCGGCGGAGGAAGAGGAGTTGGGCGGGCCATTTGTGTCGCCTATGC CGAGGAAGGCGCGGATGTCGTCGTGAATTACGCGGGTAACCATGCCGCTGCAAACGAAGTGGTTGCAATGATTGAAAAGA TGGGACGGCGTGCCGTTGCTGTTCAGGGCCGTGTTGAAATCAAGGCTGAAGCGGAGAAAACTATTCAGACTGCCGTGGAT AATTTCGGCAGAATTGACGTTCTTGTAAACAATGCCGGCGCTACAAAACCGGCAATGCTCCATAAAATGACGGAAGAACA GTGGGATGCGGTGGTTAATATCCATTTGAAAGGTCCCTTCCTGTGTGTCCAGGCGGCAGCGAAGTATTTTATGGAACAGA ATTACGGAAAAATTATCAATGTGACCTCCGTAGCCGGTCTGGTGGGTACGACGGGACAGATTAATTACAGTGCGGCCAAG GGCGGCATTCTTTCCTTCACCATGTCAGCAGCAAGGGAACTTGCACGGTTTAACGTCACATCCAATGTGATTTCCCTGGG CATTGTAACCACGGATATGACGGAAAAGATCACCACTGATGATAAATTGAAAGAAATCTACATGAGGCGTATTCTGCTCA ATCGTTATGCAGAGCCTTCCGAAGTCGCCCCGGCATTTGTTTTCTTCGGATGCGATGACTCAAAATATATAACAGGCCAG TTGCTTAAAGTTGACGGTGGTTATGGTTTGACCTAA
Upstream 100 bases:
>100_bases GATACAGAACAACAGATAAATAATTTCACAGGATCATCGAGCCAGTGAAAGCACCTCAATTGATTGATATCAACAATAAT AACGACAGGGGGATTTAGAA
Downstream 100 bases:
>100_bases ACTTCCAGATTAAGGGATTAGGATCAACAAGTTTATATCCAGCTTTTAAAGCCCTCTGAACGGGATGTAGCGTTCAGAGG GCTTTAACCCCTCGAAGTGA
Product: 3-oxoacyl- reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MGKLDGKVAVVTGGGRGVGRAICVAYAEEGADVVVNYAGNHAAANEVVAMIEKMGRRAVAVQGRVEIKAEAEKTIQTAVD NFGRIDVLVNNAGATKPAMLHKMTEEQWDAVVNIHLKGPFLCVQAAAKYFMEQNYGKIINVTSVAGLVGTTGQINYSAAK GGILSFTMSAARELARFNVTSNVISLGIVTTDMTEKITTDDKLKEIYMRRILLNRYAEPSEVAPAFVFFGCDDSKYITGQ LLKVDGGYGLT
Sequences:
>Translated_251_residues MGKLDGKVAVVTGGGRGVGRAICVAYAEEGADVVVNYAGNHAAANEVVAMIEKMGRRAVAVQGRVEIKAEAEKTIQTAVD NFGRIDVLVNNAGATKPAMLHKMTEEQWDAVVNIHLKGPFLCVQAAAKYFMEQNYGKIINVTSVAGLVGTTGQINYSAAK GGILSFTMSAARELARFNVTSNVISLGIVTTDMTEKITTDDKLKEIYMRRILLNRYAEPSEVAPAFVFFGCDDSKYITGQ LLKVDGGYGLT >Mature_250_residues GKLDGKVAVVTGGGRGVGRAICVAYAEEGADVVVNYAGNHAAANEVVAMIEKMGRRAVAVQGRVEIKAEAEKTIQTAVDN FGRIDVLVNNAGATKPAMLHKMTEEQWDAVVNIHLKGPFLCVQAAAKYFMEQNYGKIINVTSVAGLVGTTGQINYSAAKG GILSFTMSAARELARFNVTSNVISLGIVTTDMTEKITTDDKLKEIYMRRILLNRYAEPSEVAPAFVFFGCDDSKYITGQL LKVDGGYGLT
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI4504505, Length=254, Percent_Identity=37.7952755905512, Blast_Score=152, Evalue=2e-37, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=36.1867704280156, Blast_Score=143, Evalue=2e-34, Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=36.2903225806452, Blast_Score=133, Evalue=1e-31, Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=30.4878048780488, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=28.6274509803922, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=29.0196078431373, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI31542939, Length=259, Percent_Identity=30.1158301158301, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=27.6422764227642, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=29.8039215686275, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=27.2357723577236, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=34.3023255813954, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=29.5275590551181, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=24.0963855421687, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=27.3504273504274, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI209862901, Length=219, Percent_Identity=27.8538812785388, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI19923983, Length=219, Percent_Identity=27.8538812785388, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=30.4812834224599, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI210032110, Length=169, Percent_Identity=27.2189349112426, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI40254986, Length=185, Percent_Identity=27.5675675675676, Blast_Score=70, Evalue=3e-12, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=34.8360655737705, Blast_Score=157, Evalue=8e-40, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=33.6032388663968, Blast_Score=144, Evalue=5e-36, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=32.3886639676113, Blast_Score=135, Evalue=4e-33, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=30.7377049180328, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.0204081632653, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI87082100, Length=264, Percent_Identity=30.6818181818182, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=32.1138211382114, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=28.3464566929134, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=28.1632653061224, Blast_Score=99, Evalue=4e-22, Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=28.4584980237154, Blast_Score=97, Evalue=7e-22, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=26, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=26.4864864864865, Blast_Score=60, Evalue=9e-11, Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=38.6454183266932, Blast_Score=146, Evalue=1e-35, Organism=Caenorhabditis elegans, GI17568967, Length=254, Percent_Identity=34.6456692913386, Blast_Score=143, Evalue=8e-35, Organism=Caenorhabditis elegans, GI17555706, Length=262, Percent_Identity=35.8778625954198, Blast_Score=140, Evalue=9e-34, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=30.8943089430894, Blast_Score=117, Evalue=4e-27, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=29.9180327868852, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=28.2868525896414, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=30.3370786516854, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=29.8804780876494, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=29.8507462686567, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=31.25, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=28.3582089552239, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=28.0442804428044, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.1954887218045, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=29.6296296296296, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=30.2238805970149, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=27.3408239700375, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=29.7397769516729, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=31.2267657992565, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=28.7822878228782, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=26.1194029850746, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17563726, Length=279, Percent_Identity=27.5985663082437, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=28.996282527881, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=28.1407035175879, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=26.5151515151515, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=28.0612244897959, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17564282, Length=199, Percent_Identity=25.1256281407035, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=24.3243243243243, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17555612, Length=223, Percent_Identity=30.0448430493274, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71997099, Length=223, Percent_Identity=28.2511210762332, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71982365, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17508895, Length=168, Percent_Identity=25, Blast_Score=67, Evalue=9e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=255, Percent_Identity=36.8627450980392, Blast_Score=142, Evalue=3e-35, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=7e-14, Organism=Drosophila melanogaster, GI18859837, Length=257, Percent_Identity=41.2451361867704, Blast_Score=157, Evalue=8e-39, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=35.4581673306773, Blast_Score=141, Evalue=3e-34, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.0756972111554, Blast_Score=110, Evalue=9e-25, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=27.5590551181102, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=29.5546558704453, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=29.1338582677165, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=28.4046692607004, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=28.3464566929134, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=26.6129032258064, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24640492, Length=183, Percent_Identity=28.4153005464481, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24644337, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=30, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=27.1794871794872, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI281364892, Length=167, Percent_Identity=29.940119760479, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24580925, Length=213, Percent_Identity=25.3521126760563, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26878; Mature: 26747
Theoretical pI: Translated: 8.04; Mature: 8.04
Prosite motif: PS00061 ADH_SHORT ; PS00216 SUGAR_TRANSPORT_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGKLDGKVAVVTGGGRGVGRAICVAYAEEGADVVVNYAGNHAAANEVVAMIEKMGRRAVA CCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEE VQGRVEIKAEAEKTIQTAVDNFGRIDVLVNNAGATKPAMLHKMTEEQWDAVVNIHLKGPF EECEEEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCH LCVQAAAKYFMEQNYGKIINVTSVAGLVGTTGQINYSAAKGGILSFTMSAARELARFNVT HHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCH SNVISLGIVTTDMTEKITTDDKLKEIYMRRILLNRYAEPSEVAPAFVFFGCDDSKYITGQ HHEEEEEEEEECCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEE LLKVDGGYGLT EEEECCCCCCC >Mature Secondary Structure GKLDGKVAVVTGGGRGVGRAICVAYAEEGADVVVNYAGNHAAANEVVAMIEKMGRRAVA CCCCCEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEE VQGRVEIKAEAEKTIQTAVDNFGRIDVLVNNAGATKPAMLHKMTEEQWDAVVNIHLKGPF EECEEEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCH LCVQAAAKYFMEQNYGKIINVTSVAGLVGTTGQINYSAAKGGILSFTMSAARELARFNVT HHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCH SNVISLGIVTTDMTEKITTDDKLKEIYMRRILLNRYAEPSEVAPAFVFFGCDDSKYITGQ HHEEEEEEEEECCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEE LLKVDGGYGLT EEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]