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The map label for this gene is fabZ [H]

Identifier: 85860833

GI number: 85860833

Start: 2999542

End: 3000021

Strand: Direct

Name: fabZ [H]

Synonym: SYN_01695

Alternate gene names: 85860833

Gene position: 2999542-3000021 (Clockwise)

Preceding gene: 85860832

Following gene: 85860834

Centisome position: 94.35

GC content: 47.08

Gene sequence:

>480_bases
ATGGTGGCTGATCAGGAAACAATGGACCTCATTCTCAACGCGGTTCCACAAAAACATCCCTTTCGATTCATCGATGAGAT
TATCGAACTGGACGATGATCACATTGTGGGTTCTTACCGCTATCGCGAGGATGAGTACTTCTATGAGGGACACTTTCCCG
ACCGCCCAATCACTCCGGGAGTTATTCTCATTGAAACCATGGCCCAGACGGGCGTCGTCGCTTTCGGACTTTACCTGACC
ATGCGGCAGAAGGATTATTCCCTTGAAGAAACCAAACAATTGACCACCCTGTTTACTTTTGTCGAGGGTGTCGAATTTAA
CAATATTGTATCACCTGGTGAGCGGGTGATTGTCCGTGGTGAAAAAATATATTTCCGGAGGGGAAGCCTGAAAACAAGGG
TGAGTATGGAACGGGAAAATGGTGAGAATATCTGTTTTGGTGTATTAGCCGGGGCGGGGGTCATGTTAAATGAAGCATAG

Upstream 100 bases:

>100_bases
CGTCTTGGATCGCCGGAAGAGATCGCCGATTTGGTTTCCTTTCTTGCCTGCAGGGCTTCGTATATTTCAGGAACGGTCAT
TCATGTGAACGGAGGCCTGT

Downstream 100 bases:

>100_bases
AGTCGTTATTACAGGCATGGGTGTTGTGGCACCCAACGGTCATGGATTGCAGGAATTTGAAGCGGCCCTTCGCGAGGGTC
GGTCAGGCATCCGCTTTATT

Product: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MVADQETMDLILNAVPQKHPFRFIDEIIELDDDHIVGSYRYREDEYFYEGHFPDRPITPGVILIETMAQTGVVAFGLYLT
MRQKDYSLEETKQLTTLFTFVEGVEFNNIVSPGERVIVRGEKIYFRRGSLKTRVSMERENGENICFGVLAGAGVMLNEA

Sequences:

>Translated_159_residues
MVADQETMDLILNAVPQKHPFRFIDEIIELDDDHIVGSYRYREDEYFYEGHFPDRPITPGVILIETMAQTGVVAFGLYLT
MRQKDYSLEETKQLTTLFTFVEGVEFNNIVSPGERVIVRGEKIYFRRGSLKTRVSMERENGENICFGVLAGAGVMLNEA
>Mature_159_residues
MVADQETMDLILNAVPQKHPFRFIDEIIELDDDHIVGSYRYREDEYFYEGHFPDRPITPGVILIETMAQTGVVAFGLYLT
MRQKDYSLEETKQLTTLFTFVEGVEFNNIVSPGERVIVRGEKIYFRRGSLKTRVSMERENGENICFGVLAGAGVMLNEA

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=160, Percent_Identity=27.5, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 18221; Mature: 18221

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVADQETMDLILNAVPQKHPFRFIDEIIELDDDHIVGSYRYREDEYFYEGHFPDRPITPG
CCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCEEECCCCCCCCCCCC
VILIETMAQTGVVAFGLYLTMRQKDYSLEETKQLTTLFTFVEGVEFNNIVSPGERVIVRG
EEEEEEHHHCCHHEEHEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
EKIYFRRGSLKTRVSMERENGENICFGVLAGAGVMLNEA
CEEEEECCCCEEEEEEECCCCCEEEEEEECCCCEEEECC
>Mature Secondary Structure
MVADQETMDLILNAVPQKHPFRFIDEIIELDDDHIVGSYRYREDEYFYEGHFPDRPITPG
CCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEEECCCCEEECCCCCCCCCCCC
VILIETMAQTGVVAFGLYLTMRQKDYSLEETKQLTTLFTFVEGVEFNNIVSPGERVIVRG
EEEEEEHHHCCHHEEHEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
EKIYFRRGSLKTRVSMERENGENICFGVLAGAGVMLNEA
CEEEEECCCCEEEEEEECCCCCEEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA