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The map label for this gene is yngJ [H]

Identifier: 85860829

GI number: 85860829

Start: 2996001

End: 2997245

Strand: Direct

Name: yngJ [H]

Synonym: SYN_01699

Alternate gene names: 85860829

Gene position: 2996001-2997245 (Clockwise)

Preceding gene: 85860828

Following gene: 85860830

Centisome position: 94.23

GC content: 49.88

Gene sequence:

>1245_bases
TTGACGGACTTTTATACTCCGACCGGTTTAAGAAAGGATAATAATAATATGGATCTGAGCCTGACCGATACTCAACAGAT
GTATGTGACTACAGTGCAGCGTTTTGTCAAGAACGACATCCTGCCCCATGTTCTGGAAATGGATCGCAGGCATGTCTTTC
CCATGGATCTGATCAAGACTTCCTGGGAAATGGGCATCATGAATATCAGCATCCCGGAATCCATCAAAGGCTACCATGTT
GACGTAGTCTCCGCCGCACTGATCATCAGGGAACTGGCTTATGGCGATTCCGGAATTGCGACTTCAGCCATGTGCAACGA
TCTGGCCAATGTGGTTATCGCCCAGCATGGAACAGATGAACAGAAGGAGGCCTTTCTTCGCCCCTTTGTCGATTCGCCGC
TTCTTTCCGCCTTTTGTTTGACCGAACCCGGAGCAGGGTCGGATAACCTCTCCATGACATCTTTTATTTCAAAGCGCGAC
GATGGCAAGTATGTTCTCAACGGGTCTAAATGTTTTATCACCAATGCCTCTTACGCTTCGCAATTCACGGTTTTCTGCAA
GGTGGGAAAACCTTCCAGTCAGTTGATGGCCTGTGTTGTGGTTCCTGTTCCCCCATTTGTCCTGGACAAAGCGTCTCCTG
TCGATGGGATTCGGGAAATTGAACTGGCCTCCGGAGGAAAGATCACTGTCGGGAAGCCTGAGGATAAGCTGGGGCAGCGT
CTATCCAATACCGCCAGTGTGACCTTCGAAGATGTGCTCATCGAACCGGGGCAGATTATCGGTGACCGCCGGCTTGGATT
TAAGTACATCATCGACGTTCTCGATTTTGCCCGCCCCATGATCGCCGCGATCGGAGTCGGCGTGGCAAAAAAAGCCTTTG
ATCTGACCTTGTCTTATACAAAGGAACGCAAACAGTTCGGTCAGCGGCTCTGCGACATTCCCGTTGCCCGGGAAATGCTG
GTTCAAATGTGGAAAAAAGTGGAGCTTTCCGAGCTGGCTTTGCTCAAATCCGCCATCAAGATACAGGAAAATGCCACAGA
TAAGGGCATGTATTCCTCCCTGGCTAAAAATGAAGCCGCGGAAGCCGCTCTGTTCTGTGCAAACGAGGGACTCCATCTTC
ACGGCGGCTACGGGTTCACGAATGAGTATGAGATTTCCAAGCTCGTTCGTGATGTTCATATAATTGACATTTACGAGGGA
ACCCGTGAAGTCCAGAACATGATCATCGGGCGGGAACTTGTATAA

Upstream 100 bases:

>100_bases
CGGTCGGCCGCTTCGTGACTTTTTCAAGACAATCGGCATAACCTGTTCTTCCGTCACCACCCTTTCGGCTGCTGAACGTC
TTTTCCGTAATGAAAAGTGA

Downstream 100 bases:

>100_bases
TTATGTTATATCTACATGGCTTAGGACATTTTCACCCTGAAAATGTCATCAGCAATCAATTCCTGGAAGAACTCGATATC
GGCACGAACGAAGAGTGGAT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MTDFYTPTGLRKDNNNMDLSLTDTQQMYVTTVQRFVKNDILPHVLEMDRRHVFPMDLIKTSWEMGIMNISIPESIKGYHV
DVVSAALIIRELAYGDSGIATSAMCNDLANVVIAQHGTDEQKEAFLRPFVDSPLLSAFCLTEPGAGSDNLSMTSFISKRD
DGKYVLNGSKCFITNASYASQFTVFCKVGKPSSQLMACVVVPVPPFVLDKASPVDGIREIELASGGKITVGKPEDKLGQR
LSNTASVTFEDVLIEPGQIIGDRRLGFKYIIDVLDFARPMIAAIGVGVAKKAFDLTLSYTKERKQFGQRLCDIPVAREML
VQMWKKVELSELALLKSAIKIQENATDKGMYSSLAKNEAAEAALFCANEGLHLHGGYGFTNEYEISKLVRDVHIIDIYEG
TREVQNMIIGRELV

Sequences:

>Translated_414_residues
MTDFYTPTGLRKDNNNMDLSLTDTQQMYVTTVQRFVKNDILPHVLEMDRRHVFPMDLIKTSWEMGIMNISIPESIKGYHV
DVVSAALIIRELAYGDSGIATSAMCNDLANVVIAQHGTDEQKEAFLRPFVDSPLLSAFCLTEPGAGSDNLSMTSFISKRD
DGKYVLNGSKCFITNASYASQFTVFCKVGKPSSQLMACVVVPVPPFVLDKASPVDGIREIELASGGKITVGKPEDKLGQR
LSNTASVTFEDVLIEPGQIIGDRRLGFKYIIDVLDFARPMIAAIGVGVAKKAFDLTLSYTKERKQFGQRLCDIPVAREML
VQMWKKVELSELALLKSAIKIQENATDKGMYSSLAKNEAAEAALFCANEGLHLHGGYGFTNEYEISKLVRDVHIIDIYEG
TREVQNMIIGRELV
>Mature_413_residues
TDFYTPTGLRKDNNNMDLSLTDTQQMYVTTVQRFVKNDILPHVLEMDRRHVFPMDLIKTSWEMGIMNISIPESIKGYHVD
VVSAALIIRELAYGDSGIATSAMCNDLANVVIAQHGTDEQKEAFLRPFVDSPLLSAFCLTEPGAGSDNLSMTSFISKRDD
GKYVLNGSKCFITNASYASQFTVFCKVGKPSSQLMACVVVPVPPFVLDKASPVDGIREIELASGGKITVGKPEDKLGQRL
SNTASVTFEDVLIEPGQIIGDRRLGFKYIIDVLDFARPMIAAIGVGVAKKAFDLTLSYTKERKQFGQRLCDIPVAREMLV
QMWKKVELSELALLKSAIKIQENATDKGMYSSLAKNEAAEAALFCANEGLHLHGGYGFTNEYEISKLVRDVHIIDIYEGT
REVQNMIIGRELV

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=404, Percent_Identity=32.6732673267327, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI187960098, Length=404, Percent_Identity=32.6732673267327, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI4557233, Length=400, Percent_Identity=30.5, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI4501859, Length=395, Percent_Identity=32.6582278481013, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI7656849, Length=409, Percent_Identity=27.8728606356968, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI21361497, Length=387, Percent_Identity=30.4909560723514, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4501857, Length=410, Percent_Identity=25.8536585365854, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI226958412, Length=405, Percent_Identity=26.6666666666667, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI4557235, Length=414, Percent_Identity=27.0531400966184, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI76496475, Length=414, Percent_Identity=27.0531400966184, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226958414, Length=367, Percent_Identity=26.9754768392371, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4503943, Length=410, Percent_Identity=27.0731707317073, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI7669494, Length=395, Percent_Identity=26.8354430379747, Blast_Score=109, Evalue=6e-24,
Organism=Escherichia coli, GI1786223, Length=401, Percent_Identity=26.9326683291771, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87081958, Length=404, Percent_Identity=25.990099009901, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082384, Length=285, Percent_Identity=24.5614035087719, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=401, Percent_Identity=34.6633416458853, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17534899, Length=401, Percent_Identity=33.1670822942643, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17569725, Length=401, Percent_Identity=31.9201995012469, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17508101, Length=387, Percent_Identity=33.3333333333333, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17506239, Length=392, Percent_Identity=32.3979591836735, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=388, Percent_Identity=27.5773195876289, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=408, Percent_Identity=26.2254901960784, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=31.3993174061433, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71985184, Length=395, Percent_Identity=26.3291139240506, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32563615, Length=254, Percent_Identity=35.0393700787402, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17505929, Length=384, Percent_Identity=27.6041666666667, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17551932, Length=385, Percent_Identity=25.974025974026, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71982178, Length=298, Percent_Identity=30.5369127516779, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17534353, Length=403, Percent_Identity=26.0545905707196, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71985192, Length=317, Percent_Identity=27.1293375394322, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=385, Percent_Identity=24.4155844155844, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24660351, Length=405, Percent_Identity=33.8271604938272, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24646207, Length=390, Percent_Identity=28.7179487179487, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24666513, Length=392, Percent_Identity=32.3979591836735, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21356377, Length=393, Percent_Identity=29.2620865139949, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281363737, Length=354, Percent_Identity=30.5084745762712, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI21355753, Length=412, Percent_Identity=27.6699029126214, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19920834, Length=412, Percent_Identity=26.6990291262136, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45787; Mature: 45656

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFYTPTGLRKDNNNMDLSLTDTQQMYVTTVQRFVKNDILPHVLEMDRRHVFPMDLIKT
CCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHC
SWEMGIMNISIPESIKGYHVDVVSAALIIRELAYGDSGIATSAMCNDLANVVIAQHGTDE
CHHHCEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEECCCCCH
QKEAFLRPFVDSPLLSAFCLTEPGAGSDNLSMTSFISKRDDGKYVLNGSKCFITNASYAS
HHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEECCEEEEECCCCCC
QFTVFCKVGKPSSQLMACVVVPVPPFVLDKASPVDGIREIELASGGKITVGKPEDKLGQR
EEEEEEECCCCCCCEEEEEEECCCCHHCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHH
LSNTASVTFEDVLIEPGQIIGDRRLGFKYIIDVLDFARPMIAAIGVGVAKKAFDLTLSYT
HHCCCCEEEHHHEECCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
KERKQFGQRLCDIPVAREMLVQMWKKVELSELALLKSAIKIQENATDKGMYSSLAKNEAA
HHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EAALFCANEGLHLHGGYGFTNEYEISKLVRDVHIIDIYEGTREVQNMIIGRELV
HEEEEEECCCEEEECCCCCCCHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDFYTPTGLRKDNNNMDLSLTDTQQMYVTTVQRFVKNDILPHVLEMDRRHVFPMDLIKT
CCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHC
SWEMGIMNISIPESIKGYHVDVVSAALIIRELAYGDSGIATSAMCNDLANVVIAQHGTDE
CHHHCEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEECCCCCH
QKEAFLRPFVDSPLLSAFCLTEPGAGSDNLSMTSFISKRDDGKYVLNGSKCFITNASYAS
HHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEECCEEEEECCCCCC
QFTVFCKVGKPSSQLMACVVVPVPPFVLDKASPVDGIREIELASGGKITVGKPEDKLGQR
EEEEEEECCCCCCCEEEEEEECCCCHHCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHH
LSNTASVTFEDVLIEPGQIIGDRRLGFKYIIDVLDFARPMIAAIGVGVAKKAFDLTLSYT
HHCCCCEEEHHHEECCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
KERKQFGQRLCDIPVAREMLVQMWKKVELSELALLKSAIKIQENATDKGMYSSLAKNEAA
HHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EAALFCANEGLHLHGGYGFTNEYEISKLVRDVHIIDIYEGTREVQNMIIGRELV
HEEEEEECCCEEEECCCCCCCHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]