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The map label for this gene is fabD [H]

Identifier: 85860828

GI number: 85860828

Start: 2995035

End: 2996000

Strand: Direct

Name: fabD [H]

Synonym: SYN_01700

Alternate gene names: 85860828

Gene position: 2995035-2996000 (Clockwise)

Preceding gene: 85860825

Following gene: 85860829

Centisome position: 94.2

GC content: 52.38

Gene sequence:

>966_bases
ATGATTAGGGAGCCTGCCATGATTCATGAAAACTCTGCAGCCGTCGTATTCCCGGGCCAGGGATCTCAGCGGCCCGGTAT
GGGAAAAGATTTTTTTGATAATGTCCCCATATCCAGACAGACATTTGAGGAAGCATCAGATGCTCTGGGCTGGGATGTTG
CCGCTCTGTGTTTTTCCGAGGATGAACGCCTCAACCTGACGGAATTTACTCAGCCCTGTATTGTTACCACTGAAATCGCG
ATGTTCCGGGCAGTGCAGACTCTTTTTTCCTTCTCTCCCTCCTTCTATGGCGGACACAGTCTCGGTGAATTTTCAGCTCT
TGTTGCAGCCGGCGTTTTTCCATTTCAGGATACGCTGCGCATCGTTCACGAAAGAGGCCGTTTGATGCAGAACGCGGTCC
CCGTCGGTGTTGGAGGAATGGCAGCCGTTATTTTAAACGATCTGGATGTCCAGCAAATCCGCAGCCTGCTTTCCGATCTC
CCTGTGGATGTGGCCAATGAAAATTCTCTGCACCAGGTTGTGATCAGCGGAGATGCCAAAGCATTGCCCGTCGCGGAAAG
CCGCCTGACAGAGCAGTTCACGGATTCCTCCTTCCGGGTGGTTCCGTTGCGGGTCAGCGCACCCTTTCACAGCCGGTTCA
TGAAATCCATTGAAGAGCCTTTTGAGCAGGTATTGCGCGCCTCTTCACCCCTCTGGAAGTCTCAGAACGCGGATAAGGTG
ACTTCCAACTATACGGGTGGCTATCACCTTCCCACGACTGAAGCTGTTTCCACGGCTCTCGTTCTGCAGCTCAGCCACGC
CGTTCGATGGGTCGATAACATGAGAACCCTGTCTTCCTCAACAAAAAGTGTCTTTGAAGTCGGACCCGGTCGGCCGCTTC
GTGACTTTTTCAAGACAATCGGCATAACCTGTTCTTCCGTCACCACCCTTTCGGCTGCTGAACGTCTTTTCCGTAATGAA
AAGTGA

Upstream 100 bases:

>100_bases
TTCGCATCATTTTCAACTAATTGTTTTCATTTTATATTTATTTTTATATTTTAGAATTTGACTTTGGCACATGACATGCT
AATAGTACTTCCGTTTAATT

Downstream 100 bases:

>100_bases
TTGACGGACTTTTATACTCCGACCGGTTTAAGAAAGGATAATAATAATATGGATCTGAGCCTGACCGATACTCAACAGAT
GTATGTGACTACAGTGCAGC

Product: malonyl-CoA-[acyl-carrier-protein] transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIREPAMIHENSAAVVFPGQGSQRPGMGKDFFDNVPISRQTFEEASDALGWDVAALCFSEDERLNLTEFTQPCIVTTEIA
MFRAVQTLFSFSPSFYGGHSLGEFSALVAAGVFPFQDTLRIVHERGRLMQNAVPVGVGGMAAVILNDLDVQQIRSLLSDL
PVDVANENSLHQVVISGDAKALPVAESRLTEQFTDSSFRVVPLRVSAPFHSRFMKSIEEPFEQVLRASSPLWKSQNADKV
TSNYTGGYHLPTTEAVSTALVLQLSHAVRWVDNMRTLSSSTKSVFEVGPGRPLRDFFKTIGITCSSVTTLSAAERLFRNE
K

Sequences:

>Translated_321_residues
MIREPAMIHENSAAVVFPGQGSQRPGMGKDFFDNVPISRQTFEEASDALGWDVAALCFSEDERLNLTEFTQPCIVTTEIA
MFRAVQTLFSFSPSFYGGHSLGEFSALVAAGVFPFQDTLRIVHERGRLMQNAVPVGVGGMAAVILNDLDVQQIRSLLSDL
PVDVANENSLHQVVISGDAKALPVAESRLTEQFTDSSFRVVPLRVSAPFHSRFMKSIEEPFEQVLRASSPLWKSQNADKV
TSNYTGGYHLPTTEAVSTALVLQLSHAVRWVDNMRTLSSSTKSVFEVGPGRPLRDFFKTIGITCSSVTTLSAAERLFRNE
K
>Mature_321_residues
MIREPAMIHENSAAVVFPGQGSQRPGMGKDFFDNVPISRQTFEEASDALGWDVAALCFSEDERLNLTEFTQPCIVTTEIA
MFRAVQTLFSFSPSFYGGHSLGEFSALVAAGVFPFQDTLRIVHERGRLMQNAVPVGVGGMAAVILNDLDVQQIRSLLSDL
PVDVANENSLHQVVISGDAKALPVAESRLTEQFTDSSFRVVPLRVSAPFHSRFMKSIEEPFEQVLRASSPLWKSQNADKV
TSNYTGGYHLPTTEAVSTALVLQLSHAVRWVDNMRTLSSSTKSVFEVGPGRPLRDFFKTIGITCSSVTTLSAAERLFRNE
K

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=318, Percent_Identity=31.4465408805031, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1787334, Length=294, Percent_Identity=37.4149659863946, Blast_Score=157, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI71984332, Length=305, Percent_Identity=30.4918032786885, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=308, Percent_Identity=28.8961038961039, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24665753, Length=326, Percent_Identity=27.6073619631902, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 35279; Mature: 35279

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREPAMIHENSAAVVFPGQGSQRPGMGKDFFDNVPISRQTFEEASDALGWDVAALCFSE
CCCCCCEEECCCEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCHHHHHHEECC
DERLNLTEFTQPCIVTTEIAMFRAVQTLFSFSPSFYGGHSLGEFSALVAAGVFPFQDTLR
CCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
IVHERGRLMQNAVPVGVGGMAAVILNDLDVQQIRSLLSDLPVDVANENSLHQVVISGDAK
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC
ALPVAESRLTEQFTDSSFRVVPLRVSAPFHSRFMKSIEEPFEQVLRASSPLWKSQNADKV
CCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
TSNYTGGYHLPTTEAVSTALVLQLSHAVRWVDNMRTLSSSTKSVFEVGPGRPLRDFFKTI
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GITCSSVTTLSAAERLFRNEK
CCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIREPAMIHENSAAVVFPGQGSQRPGMGKDFFDNVPISRQTFEEASDALGWDVAALCFSE
CCCCCCEEECCCEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCHHHHHHEECC
DERLNLTEFTQPCIVTTEIAMFRAVQTLFSFSPSFYGGHSLGEFSALVAAGVFPFQDTLR
CCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
IVHERGRLMQNAVPVGVGGMAAVILNDLDVQQIRSLLSDLPVDVANENSLHQVVISGDAK
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCC
ALPVAESRLTEQFTDSSFRVVPLRVSAPFHSRFMKSIEEPFEQVLRASSPLWKSQNADKV
CCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
TSNYTGGYHLPTTEAVSTALVLQLSHAVRWVDNMRTLSSSTKSVFEVGPGRPLRDFFKTI
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GITCSSVTTLSAAERLFRNEK
CCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]