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The map label for this gene is guaA [H]

Identifier: 85860789

GI number: 85860789

Start: 2956829

End: 2957425

Strand: Direct

Name: guaA [H]

Synonym: SYN_00331

Alternate gene names: 85860789

Gene position: 2956829-2957425 (Clockwise)

Preceding gene: 85860788

Following gene: 85860790

Centisome position: 93.0

GC content: 54.27

Gene sequence:

>597_bases
ATGGGCTTGAATACTAAAAACAGATGCGAATGGTGCGGTACGAATCCGCTGTATGTGGAATACCACGACAACGAATGGGG
AGTGCCTCTGCACGATGATCGTGGCCTTTTCGAGCTGCTGACTCTGGAGGGCGCGCAGGCAGGTCTGAGCTGGCTGACCA
TCCTCAGGAAACGAGAGCACTATCGCAATGCATTCCACGGGTTCGATCCGCAGAAGATTGCCGGCTATTCGGAAAATGAC
GTTCAGCTCCTGCTTGGTGACTCCGGCATCGTGCGGAACCGCCGGAAGATCGAATCGACTGTCGGCAATGCGCGGTGTGT
GCTCGCCATTCAAGAAGAGTTCGGTTCCTTCGATGCTTTCCTCTGGAGTTATGTCCATCATCAGCCTGTTCAGAATGCCT
GGCGATCGCTGACCGAGCTGCCTGCAAGAACGGCGCTATCGGACACGATAAGCAAAGATCTGAAGAAACGGGGTTTCAAC
TTTGTGGGATCAACCATTTGTTATGCCTTCATGCAGGCGGTCGGCATGGTGAATGACCACGTCGTTACGTGCTTCCGCCA
CGAACAGGTAAAGAAGATCGCCCGGCCAGGGGATTGA

Upstream 100 bases:

>100_bases
AAATACAGTCCGTCTTCTCAAAACGACGCACGAGAACTGCTCAGGGAACAGGTTAAGGGGTGAGAATTGGAATCAGTCAC
GCAAGGATGAATTAAGCAGA

Downstream 100 bases:

>100_bases
AAACAGAATCCATGCGATTCGTCGCAATCATCCGTTCAGTTCCTCCTCTTAAGTTAAGCGTACAGGTCGAAATACTGCAT
GTCTGATTCGCTTCCATCAA

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MGLNTKNRCEWCGTNPLYVEYHDNEWGVPLHDDRGLFELLTLEGAQAGLSWLTILRKREHYRNAFHGFDPQKIAGYSEND
VQLLLGDSGIVRNRRKIESTVGNARCVLAIQEEFGSFDAFLWSYVHHQPVQNAWRSLTELPARTALSDTISKDLKKRGFN
FVGSTICYAFMQAVGMVNDHVVTCFRHEQVKKIARPGD

Sequences:

>Translated_198_residues
MGLNTKNRCEWCGTNPLYVEYHDNEWGVPLHDDRGLFELLTLEGAQAGLSWLTILRKREHYRNAFHGFDPQKIAGYSEND
VQLLLGDSGIVRNRRKIESTVGNARCVLAIQEEFGSFDAFLWSYVHHQPVQNAWRSLTELPARTALSDTISKDLKKRGFN
FVGSTICYAFMQAVGMVNDHVVTCFRHEQVKKIARPGD
>Mature_197_residues
GLNTKNRCEWCGTNPLYVEYHDNEWGVPLHDDRGLFELLTLEGAQAGLSWLTILRKREHYRNAFHGFDPQKIAGYSENDV
QLLLGDSGIVRNRRKIESTVGNARCVLAIQEEFGSFDAFLWSYVHHQPVQNAWRSLTELPARTALSDTISKDLKKRGFNF
VGSTICYAFMQAVGMVNDHVVTCFRHEQVKKIARPGD

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=177, Percent_Identity=55.9322033898305, Blast_Score=224, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 22587; Mature: 22456

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLNTKNRCEWCGTNPLYVEYHDNEWGVPLHDDRGLFELLTLEGAQAGLSWLTILRKREH
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
YRNAFHGFDPQKIAGYSENDVQLLLGDSGIVRNRRKIESTVGNARCVLAIQEEFGSFDAF
HHHHHCCCCCHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCHHHH
LWSYVHHQPVQNAWRSLTELPARTALSDTISKDLKKRGFNFVGSTICYAFMQAVGMVNDH
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHH
VVTCFRHEQVKKIARPGD
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GLNTKNRCEWCGTNPLYVEYHDNEWGVPLHDDRGLFELLTLEGAQAGLSWLTILRKREH
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
YRNAFHGFDPQKIAGYSENDVQLLLGDSGIVRNRRKIESTVGNARCVLAIQEEFGSFDAF
HHHHHCCCCCHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCHHHH
LWSYVHHQPVQNAWRSLTELPARTALSDTISKDLKKRGFNFVGSTICYAFMQAVGMVNDH
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHH
VVTCFRHEQVKKIARPGD
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]