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The map label for this gene is perR [H]

Identifier: 85860725

GI number: 85860725

Start: 2906490

End: 2906942

Strand: Direct

Name: perR [H]

Synonym: SYN_02397

Alternate gene names: 85860725

Gene position: 2906490-2906942 (Clockwise)

Preceding gene: 85860710

Following gene: 85860726

Centisome position: 91.42

GC content: 54.53

Gene sequence:

>453_bases
ATGGACCCCTTAGAGGAAAAAATCGCCGCCTTTGAGACGGCCTGCCGCAAAGCCGGCCTCAAGGTCACCCGTCAGCGCCG
GGAGATCTACCGCGAACTCCTGCTGTCGACCGATCATCCCTCTGCGGAGGCCCTGCATCAGCGTCTCCGTGGCATACTTC
CCGGAATTTCCCTGGACACGGTCTACAGAACCCTCGCGACCCTTGCAAGCGCGGGATTGATCAAGAAGGTGGAAACCTCG
GAAAGTCTCTCCCGTTTTGAGGCAACGTTCAGCCGGCATCACCATCTCATCTGTCGCCAGTGTGGTCAGATTCAGGATTT
TACATGGTCTTTTCTCGACGAGGTCTCTCTTCCCGATGAAATCGGAGACTGGGGCCGCATCGATTCCAAAAACGTCGTGG
TTTATGGCATCTGCAGTACCTGTCTCAATCAAACTCACAAAAAGAATTTCTGA

Upstream 100 bases:

>100_bases
TTGTTTTTTACTTTCATTTCAATCCTGCCTGGGAACGTTAAGATTCAACAGGTCTCTTCATGATTTTTCGCGAAATAACA
TTGGGTAAGCAAGGCAAAGC

Downstream 100 bases:

>100_bases
AATAAACATTGTTTTTGCCATCTAAATAAGATAATTTCTTATTTAGAAAATCGTCAGCGGCCATTGTTAATAGTTCAGCC
AACCTTTCCCGGCTTTCTGC

Product: ferric uptake regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MDPLEEKIAAFETACRKAGLKVTRQRREIYRELLLSTDHPSAEALHQRLRGILPGISLDTVYRTLATLASAGLIKKVETS
ESLSRFEATFSRHHHLICRQCGQIQDFTWSFLDEVSLPDEIGDWGRIDSKNVVVYGICSTCLNQTHKKNF

Sequences:

>Translated_150_residues
MDPLEEKIAAFETACRKAGLKVTRQRREIYRELLLSTDHPSAEALHQRLRGILPGISLDTVYRTLATLASAGLIKKVETS
ESLSRFEATFSRHHHLICRQCGQIQDFTWSFLDEVSLPDEIGDWGRIDSKNVVVYGICSTCLNQTHKKNF
>Mature_150_residues
MDPLEEKIAAFETACRKAGLKVTRQRREIYRELLLSTDHPSAEALHQRLRGILPGISLDTVYRTLATLASAGLIKKVETS
ESLSRFEATFSRHHHLICRQCGQIQDFTWSFLDEVSLPDEIGDWGRIDSKNVVVYGICSTCLNQTHKKNF

Specific function: Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=130, Percent_Identity=36.1538461538462, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17047; Mature: 17047

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLEEKIAAFETACRKAGLKVTRQRREIYRELLLSTDHPSAEALHQRLRGILPGISLDT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHH
VYRTLATLASAGLIKKVETSESLSRFEATFSRHHHLICRQCGQIQDFTWSFLDEVSLPDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHH
IGDWGRIDSKNVVVYGICSTCLNQTHKKNF
CCCCCCCCCCCEEEEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MDPLEEKIAAFETACRKAGLKVTRQRREIYRELLLSTDHPSAEALHQRLRGILPGISLDT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHH
VYRTLATLASAGLIKKVETSESLSRFEATFSRHHHLICRQCGQIQDFTWSFLDEVSLPDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHH
IGDWGRIDSKNVVVYGICSTCLNQTHKKNF
CCCCCCCCCCCEEEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA