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The map label for this gene is tpiA [H]

Identifier: 85860570

GI number: 85860570

Start: 2746197

End: 2746589

Strand: Direct

Name: tpiA [H]

Synonym: SYN_03790

Alternate gene names: 85860570

Gene position: 2746197-2746589 (Clockwise)

Preceding gene: 85860569

Following gene: 85860571

Centisome position: 86.38

GC content: 57.25

Gene sequence:

>393_bases
TTGAAGCCGATTTTCTGCATCGGTGAAACCCTGGCCGAGAGGGAATCCGGCCAGACCTTCAGTGTCCTGGAAAGACAGAT
AAAACAGGGGTTGAATTCTTTTAACGTCAGTGATATACGGCACCTCGTCGTTGCCTATGAACCCGTGTGGGCCATCGGCA
CGGGCAAGACCGCAACGCCGGATCAGGCACAGGAGGCCCATGCCTTCATCCGCTCGACGATCGGCGGTGTTTTTGGAGCG
GAATTCGCCTCCGAACACGCCATCCTGTATGGAGGCAGCGTGAATCCCGAGAACATCGCGTCGCTGATGAGCCGGCCGGA
TATCAACGGGGCGCTGGTCGGCGGGGCAAGCCTGAAGGTTGATTCCTTTCTCAGGATCATCCTGTACCCGTAA

Upstream 100 bases:

>100_bases
GCTGCGACTCGGTCATCATCGGTCATTCAGAAAGGCGCACCCTTTTCGGAGAAACCGACGCGATCATCAATAAAAAAATC
CGGGCGGCCTGCGAAGCGGC

Downstream 100 bases:

>100_bases
GAGGGTTGATAAAAAATTTAAAGAGGCAAAATCGTGCACATTCTGATTAACATTTTACATATTCTGTCCTGTTTCGTTCT
TGTCCTGGTCGTTCTTCTCC

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MKPIFCIGETLAERESGQTFSVLERQIKQGLNSFNVSDIRHLVVAYEPVWAIGTGKTATPDQAQEAHAFIRSTIGGVFGA
EFASEHAILYGGSVNPENIASLMSRPDINGALVGGASLKVDSFLRIILYP

Sequences:

>Translated_130_residues
MKPIFCIGETLAERESGQTFSVLERQIKQGLNSFNVSDIRHLVVAYEPVWAIGTGKTATPDQAQEAHAFIRSTIGGVFGA
EFASEHAILYGGSVNPENIASLMSRPDINGALVGGASLKVDSFLRIILYP
>Mature_130_residues
MKPIFCIGETLAERESGQTFSVLERQIKQGLNSFNVSDIRHLVVAYEPVWAIGTGKTATPDQAQEAHAFIRSTIGGVFGA
EFASEHAILYGGSVNPENIASLMSRPDINGALVGGASLKVDSFLRIILYP

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=124, Percent_Identity=50.8064516129032, Blast_Score=109, Evalue=6e-25,
Organism=Homo sapiens, GI226529917, Length=124, Percent_Identity=50.8064516129032, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI1790353, Length=127, Percent_Identity=54.3307086614173, Blast_Score=132, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17536593, Length=127, Percent_Identity=51.9685039370079, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320255, Length=124, Percent_Identity=51.6129032258064, Blast_Score=120, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28572008, Length=127, Percent_Identity=52.755905511811, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28572006, Length=127, Percent_Identity=52.755905511811, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28572004, Length=127, Percent_Identity=52.755905511811, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 13979; Mature: 13979

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIFCIGETLAERESGQTFSVLERQIKQGLNSFNVSDIRHLVVAYEPVWAIGTGKTATP
CCCEEECHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCCCCCC
DQAQEAHAFIRSTIGGVFGAEFASEHAILYGGSVNPENIASLMSRPDINGALVGGASLKV
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCH
DSFLRIILYP
HHHHEEEECC
>Mature Secondary Structure
MKPIFCIGETLAERESGQTFSVLERQIKQGLNSFNVSDIRHLVVAYEPVWAIGTGKTATP
CCCEEECHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEECCCCCCCC
DQAQEAHAFIRSTIGGVFGAEFASEHAILYGGSVNPENIASLMSRPDINGALVGGASLKV
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCH
DSFLRIILYP
HHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA