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The map label for this gene is dsbD [H]

Identifier: 85860547

GI number: 85860547

Start: 2725596

End: 2726312

Strand: Direct

Name: dsbD [H]

Synonym: SYN_01815

Alternate gene names: 85860547

Gene position: 2725596-2726312 (Clockwise)

Preceding gene: 85860546

Following gene: 85860548

Centisome position: 85.73

GC content: 55.93

Gene sequence:

>717_bases
ATGATCGACTCTTTACTGAACAACCTGAGCGGCTACATGGCGGACTCCAGTTTCGCCGCTTACCTGGCTGCGTATCTGGG
GGGGCTTCTGGTCAGTTTCACCCCCTGCGTTTACCCGGTCATGCCGCTCGTAATCGCCTACATCGGCGCCCGGGGCTCCC
GATCCCGTCTTTACGGGTTTCTCCTTTCTTTAACCTATGTTCTTGGTCTGTCCCTGACCTATGCCGTTCTCGGCGGCATA
TCCGCGTTGACAGGACGATTGTTCGGGACCATACAGAGCAGTTTCTGGGTTGCTTTTCTGGTGGCCAATGTCTGCATTCT
CATGGGGCTGGCCATGCTGGATGTCTTCACGATTCAAATCCGGATTCCCGGATTCGCGACTTCGCCACAGACGGGCGACA
TGCATAAAAGCGTTATCGGCAGTTTCCTGGTCGGCATCACCTCCGGGTTGCTTATAGGGCCCTGCTCGGCCCCGGTATTT
TCCGTTCTGCTCGCCTATGTCGCCACCCGGCAGAATCTCTTTTTCGGTATGAGTCTTCTGTTTGTTTTTGCTCTGGGCAT
GGGGACCCTGCTGGTTGCCATCGGCTCTTTCGCAGGTCTGATGGCCAGCCTCCCCAAGTCGGGCATGTGGATGGTGCGGA
TCAAACACGGTTGCGGCTGGATACTCATCGCCACGGGAGAATATTTTCTGATTCAGGCCGGGAAATCTCTGGTCTGA

Upstream 100 bases:

>100_bases
ATTTCGAGAATTCCCGTCCCGCCCGATCCTGCGTCGCGGTCAGTCGGCTGCCCAAGGATGCCCTGCTGGAAATCGAAGCG
GTCGCCCTGTGTGAGGATTC

Downstream 100 bases:

>100_bases
TCCAAAAAGACAGAAACAGGAGGGTTCAAACCATGAAGTTTCCCCGTATTCTTTTCCGGCTTGCCGGAATGATTCTTTTG
ATTTTCTGTCTGGAAGGCTG

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MIDSLLNNLSGYMADSSFAAYLAAYLGGLLVSFTPCVYPVMPLVIAYIGARGSRSRLYGFLLSLTYVLGLSLTYAVLGGI
SALTGRLFGTIQSSFWVAFLVANVCILMGLAMLDVFTIQIRIPGFATSPQTGDMHKSVIGSFLVGITSGLLIGPCSAPVF
SVLLAYVATRQNLFFGMSLLFVFALGMGTLLVAIGSFAGLMASLPKSGMWMVRIKHGCGWILIATGEYFLIQAGKSLV

Sequences:

>Translated_238_residues
MIDSLLNNLSGYMADSSFAAYLAAYLGGLLVSFTPCVYPVMPLVIAYIGARGSRSRLYGFLLSLTYVLGLSLTYAVLGGI
SALTGRLFGTIQSSFWVAFLVANVCILMGLAMLDVFTIQIRIPGFATSPQTGDMHKSVIGSFLVGITSGLLIGPCSAPVF
SVLLAYVATRQNLFFGMSLLFVFALGMGTLLVAIGSFAGLMASLPKSGMWMVRIKHGCGWILIATGEYFLIQAGKSLV
>Mature_238_residues
MIDSLLNNLSGYMADSSFAAYLAAYLGGLLVSFTPCVYPVMPLVIAYIGARGSRSRLYGFLLSLTYVLGLSLTYAVLGGI
SALTGRLFGTIQSSFWVAFLVANVCILMGLAMLDVFTIQIRIPGFATSPQTGDMHKSVIGSFLVGITSGLLIGPCSAPVF
SVLLAYVATRQNLFFGMSLLFVFALGMGTLLVAIGSFAGLMASLPKSGMWMVRIKHGCGWILIATGEYFLIQAGKSLV

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=210, Percent_Identity=33.8095238095238, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 25248; Mature: 25248

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSLLNNLSGYMADSSFAAYLAAYLGGLLVSFTPCVYPVMPLVIAYIGARGSRSRLYGF
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLSLTYVLGLSLTYAVLGGISALTGRLFGTIQSSFWVAFLVANVCILMGLAMLDVFTIQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
RIPGFATSPQTGDMHKSVIGSFLVGITSGLLIGPCSAPVFSVLLAYVATRQNLFFGMSLL
EECCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVFALGMGTLLVAIGSFAGLMASLPKSGMWMVRIKHGCGWILIATGEYFLIQAGKSLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCEEEEECCCCCC
>Mature Secondary Structure
MIDSLLNNLSGYMADSSFAAYLAAYLGGLLVSFTPCVYPVMPLVIAYIGARGSRSRLYGF
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LLSLTYVLGLSLTYAVLGGISALTGRLFGTIQSSFWVAFLVANVCILMGLAMLDVFTIQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
RIPGFATSPQTGDMHKSVIGSFLVGITSGLLIGPCSAPVFSVLLAYVATRQNLFFGMSLL
EECCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVFALGMGTLLVAIGSFAGLMASLPKSGMWMVRIKHGCGWILIATGEYFLIQAGKSLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]