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The map label for this gene is hflX [H]

Identifier: 85860494

GI number: 85860494

Start: 2675184

End: 2676851

Strand: Direct

Name: hflX [H]

Synonym: SYN_01762

Alternate gene names: 85860494

Gene position: 2675184-2676851 (Clockwise)

Preceding gene: 85860493

Following gene: 85860497

Centisome position: 84.14

GC content: 61.27

Gene sequence:

>1668_bases
GTGCGTCTTTTCCAGAAGGAGCTATCGACCATCCAGAAAATATACGGAAATCTAACCGGCTTGAAGCCGATCCAGATCAA
ACGCCTGGAGCAGTTCTACCGGAGGCGGGTGCCGCCCGATGCAATCGTCACCCAGGAAATGGCCCGTCAGCTCACGGAAC
TCTCCCGGGAGCTCAACCGGCAGCTGGGGGTATTGCTCAGCCGGCGGGGCGAAGTGGCCTGTGTGATCGTCGGCACCCAT
AAGGGCATCCTCATCCCCAGCCTGGAGGGATTCCGTTCCTCATCGGCCCGTTTCAAGGGGCTCCGCCTGATTCATACCCA
CTTGGGTCCCGACCCCCTGAATGCCGAAGACCTCAGCGACCTGGCGCTTCTGCGCCTCGATCTCATCTGCGCCGTGGAAA
CGGGCCCCGACGGTCTCCCCGGCATCGTCCACACTGCCCATCTGATTCCCGAAAATCCCGACGGCGGCTACTGGCGGGTT
GAACCGCCCCAACGAATCTCCGATCTGAAGGCGGATTTCCTTTCCTTCATCGGCGCCCTGGAAAACGAGTTCGCCCGAAC
CCAGCGTTCCCGCAAGGTGGATTCCGCCGACCGGGCGATTCTTCTTCGCGTCGAAACGAATCCCCTCTTCGACAGCGAGG
GGTCCCTGGAGGAGCTCAGGGAACTGGCCCACTCCTGCAACGTGGAGGTATTTGACCGGATCATCCAGCACCGCCCCCAG
CTTGACCCGAGGTATCTCCTCGGCAAGGGAAAGCTCGCCGACGTGATCATCAAGGCCCTGCAGATCGGCGCCAACCTGCT
CATCTTCGATCACGAGCTGACGCCCGCCCAGGTTCGTTCCATTGCGGATTTCACGGAGATGAAGGTCATCGACCGGACGC
AGGTCATCCTGGACATCTTCGCGCAGCGCGCCCACAGCCGGGAAGGAAAGATTCAGGTGGAGCTCGCCCAGTTGAAATAT
CTTCTGCCCCGCCTGGCGACGCGCCATACGGGCATGTCCCGCCTCACGGGGGGAATCGGCGGACGGGGACCGGGGGAAAC
GAAGCTGGAAGTCAATCGGCGGCGGGTGAGGGACCGGATTCTGCATCTGGAGGAAGACATCCGGAATATTGAAAAGGCCC
GGGGGCAGCGGCGGCTGAAACGGGAACGGACGGGTCTGCCGGTGATCTCGATTGTAGGCTACACCAACGCCGGAAAATCC
ACCCTGCTCAACACCCTCACGAAAAGCCGCGTCTTCACGGAAGACCGTCTCTTCGCCACCCTGGACCCGAAAAGTTCACG
GCTGCGCTTTCCCCGGGATGCGGAAGCCGTCATTACCGATACGGTGGGCTTCATCCGCGACCTCCCGGCGGATCTCTTCG
CCGCCTTCAAGGCCACGCTGGAGGAACTCTATGAAGCGGACATCCTCCTCCACGTCATCGATGTAAGCAACCCCGGCTTC
GAAAGCCACATCGCCGCCGTGGAAAAAATCCTGGAAGAGATCGGCATACAGGGAAAAGCCACCCTCCGGGTCTTCAACAA
GGCCGACCGCTTTGCCGACAAGGCCCTGCTGTCGACCCTCTGCCGGCGCTTCAACGCCATCGCCGTATCGGCCCTTCAAC
CGGATAGTCTGGGGCCGCTCATGGAGCAACTGGAAGAGATCGTTTCCCCCCCAGATGAAACCCGATGA

Upstream 100 bases:

>100_bases
TTTTTTCATCTCCTTCCTTGACCGGATGAGACACATCTGATAATTTTTCCCGTCAGCAGGAATAAAATCATTTCCGCAAC
CGATCCGGGCGCTCATTTCA

Downstream 100 bases:

>100_bases
GATCGGCATAACGTCGGGACGCCCCGGCATTGGCGGTGACGGCAAGACGGCCCTGTTCGCCCCGGCGTCTCAACTCATCG
GGATCCGCCAGGAGCGACAG

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MRLFQKELSTIQKIYGNLTGLKPIQIKRLEQFYRRRVPPDAIVTQEMARQLTELSRELNRQLGVLLSRRGEVACVIVGTH
KGILIPSLEGFRSSSARFKGLRLIHTHLGPDPLNAEDLSDLALLRLDLICAVETGPDGLPGIVHTAHLIPENPDGGYWRV
EPPQRISDLKADFLSFIGALENEFARTQRSRKVDSADRAILLRVETNPLFDSEGSLEELRELAHSCNVEVFDRIIQHRPQ
LDPRYLLGKGKLADVIIKALQIGANLLIFDHELTPAQVRSIADFTEMKVIDRTQVILDIFAQRAHSREGKIQVELAQLKY
LLPRLATRHTGMSRLTGGIGGRGPGETKLEVNRRRVRDRILHLEEDIRNIEKARGQRRLKRERTGLPVISIVGYTNAGKS
TLLNTLTKSRVFTEDRLFATLDPKSSRLRFPRDAEAVITDTVGFIRDLPADLFAAFKATLEELYEADILLHVIDVSNPGF
ESHIAAVEKILEEIGIQGKATLRVFNKADRFADKALLSTLCRRFNAIAVSALQPDSLGPLMEQLEEIVSPPDETR

Sequences:

>Translated_555_residues
MRLFQKELSTIQKIYGNLTGLKPIQIKRLEQFYRRRVPPDAIVTQEMARQLTELSRELNRQLGVLLSRRGEVACVIVGTH
KGILIPSLEGFRSSSARFKGLRLIHTHLGPDPLNAEDLSDLALLRLDLICAVETGPDGLPGIVHTAHLIPENPDGGYWRV
EPPQRISDLKADFLSFIGALENEFARTQRSRKVDSADRAILLRVETNPLFDSEGSLEELRELAHSCNVEVFDRIIQHRPQ
LDPRYLLGKGKLADVIIKALQIGANLLIFDHELTPAQVRSIADFTEMKVIDRTQVILDIFAQRAHSREGKIQVELAQLKY
LLPRLATRHTGMSRLTGGIGGRGPGETKLEVNRRRVRDRILHLEEDIRNIEKARGQRRLKRERTGLPVISIVGYTNAGKS
TLLNTLTKSRVFTEDRLFATLDPKSSRLRFPRDAEAVITDTVGFIRDLPADLFAAFKATLEELYEADILLHVIDVSNPGF
ESHIAAVEKILEEIGIQGKATLRVFNKADRFADKALLSTLCRRFNAIAVSALQPDSLGPLMEQLEEIVSPPDETR
>Mature_555_residues
MRLFQKELSTIQKIYGNLTGLKPIQIKRLEQFYRRRVPPDAIVTQEMARQLTELSRELNRQLGVLLSRRGEVACVIVGTH
KGILIPSLEGFRSSSARFKGLRLIHTHLGPDPLNAEDLSDLALLRLDLICAVETGPDGLPGIVHTAHLIPENPDGGYWRV
EPPQRISDLKADFLSFIGALENEFARTQRSRKVDSADRAILLRVETNPLFDSEGSLEELRELAHSCNVEVFDRIIQHRPQ
LDPRYLLGKGKLADVIIKALQIGANLLIFDHELTPAQVRSIADFTEMKVIDRTQVILDIFAQRAHSREGKIQVELAQLKY
LLPRLATRHTGMSRLTGGIGGRGPGETKLEVNRRRVRDRILHLEEDIRNIEKARGQRRLKRERTGLPVISIVGYTNAGKS
TLLNTLTKSRVFTEDRLFATLDPKSSRLRFPRDAEAVITDTVGFIRDLPADLFAAFKATLEELYEADILLHVIDVSNPGF
ESHIAAVEKILEEIGIQGKATLRVFNKADRFADKALLSTLCRRFNAIAVSALQPDSLGPLMEQLEEIVSPPDETR

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=236, Percent_Identity=33.0508474576271, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI310133116, Length=226, Percent_Identity=33.6283185840708, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=34.4339622641509, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=34.4339622641509, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=34.4339622641509, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=34.4339622641509, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1790615, Length=322, Percent_Identity=46.2732919254658, Blast_Score=276, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17561038, Length=299, Percent_Identity=27.7591973244147, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24650079, Length=351, Percent_Identity=30.4843304843305, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 62387; Mature: 62387

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFQKELSTIQKIYGNLTGLKPIQIKRLEQFYRRRVPPDAIVTQEMARQLTELSRELNR
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QLGVLLSRRGEVACVIVGTHKGILIPSLEGFRSSSARFKGLRLIHTHLGPDPLNAEDLSD
HHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCCCHHHHCCEEEEECCCCCCCCHHHHHH
LALLRLDLICAVETGPDGLPGIVHTAHLIPENPDGGYWRVEPPQRISDLKADFLSFIGAL
HHHHHHHHHEEEECCCCCCCHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
ENEFARTQRSRKVDSADRAILLRVETNPLFDSEGSLEELRELAHSCNVEVFDRIIQHRPQ
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCC
LDPRYLLGKGKLADVIIKALQIGANLLIFDHELTPAQVRSIADFTEMKVIDRTQVILDIF
CCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQRAHSREGKIQVELAQLKYLLPRLATRHTGMSRLTGGIGGRGPGETKLEVNRRRVRDRI
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
LHLEEDIRNIEKARGQRRLKRERTGLPVISIVGYTNAGKSTLLNTLTKSRVFTEDRLFAT
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
LDPKSSRLRFPRDAEAVITDTVGFIRDLPADLFAAFKATLEELYEADILLHVIDVSNPGF
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCH
ESHIAAVEKILEEIGIQGKATLRVFNKADRFADKALLSTLCRRFNAIAVSALQPDSLGPL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHH
MEQLEEIVSPPDETR
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MRLFQKELSTIQKIYGNLTGLKPIQIKRLEQFYRRRVPPDAIVTQEMARQLTELSRELNR
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
QLGVLLSRRGEVACVIVGTHKGILIPSLEGFRSSSARFKGLRLIHTHLGPDPLNAEDLSD
HHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCCCHHHHCCEEEEECCCCCCCCHHHHHH
LALLRLDLICAVETGPDGLPGIVHTAHLIPENPDGGYWRVEPPQRISDLKADFLSFIGAL
HHHHHHHHHEEEECCCCCCCHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
ENEFARTQRSRKVDSADRAILLRVETNPLFDSEGSLEELRELAHSCNVEVFDRIIQHRPQ
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCC
LDPRYLLGKGKLADVIIKALQIGANLLIFDHELTPAQVRSIADFTEMKVIDRTQVILDIF
CCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AQRAHSREGKIQVELAQLKYLLPRLATRHTGMSRLTGGIGGRGPGETKLEVNRRRVRDRI
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
LHLEEDIRNIEKARGQRRLKRERTGLPVISIVGYTNAGKSTLLNTLTKSRVFTEDRLFAT
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
LDPKSSRLRFPRDAEAVITDTVGFIRDLPADLFAAFKATLEELYEADILLHVIDVSNPGF
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCH
ESHIAAVEKILEEIGIQGKATLRVFNKADRFADKALLSTLCRRFNAIAVSALQPDSLGPL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHH
MEQLEEIVSPPDETR
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]