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The map label for this gene is sugE [H]

Identifier: 85860323

GI number: 85860323

Start: 2504902

End: 2505258

Strand: Direct

Name: sugE [H]

Synonym: SYN_01248

Alternate gene names: 85860323

Gene position: 2504902-2505258 (Clockwise)

Preceding gene: 85860322

Following gene: 85860338

Centisome position: 78.79

GC content: 50.42

Gene sequence:

>357_bases
TTGTATCGGGCCCCGATTATTCTGAAAGGTATCTTCATGGACTGGATTATTATCGTACTCGCTGGATTATTTGAGACCGG
ATGGGCAATTGGCCTTAAATACACCGACGGCTTTACCCGCTTATGGCCAACCGTCGGCACCGTTTTTTCAATGGTAATCA
GCCTTGCTCTGCTCGGCATTGCAATGAAATCAATCCCGGTCGGTACAGCCTATGCCGTCTGGGTAGGCATTGGTGCTGTC
GGTACGGCAATGCTGGGCATTGTCTTACTTGGTGAACCGGTCAATTCCGGACGGATATTAAGCCTGGCACTTATCATTGC
GGGCATTGTCGGCCTCAAGCTGACGACTCAATCCTGA

Upstream 100 bases:

>100_bases
TCCCGGCCTTCGGAAGGGCCGCAACAGTTGATCTGATCTCTATCGGAGAACTTGTCGATTATGGCCATGGACAGCCTCAT
TCCACTGTTGACGATCAGAT

Downstream 100 bases:

>100_bases
AGAGGAAATGGGTTTTTCTCCACTTCCCCGATCACCCAGTATTGAGTTCTGCGCAGCAGACTCCTCATCATTCCTTACAC
TTTCCCGAGTAAAAAGCCGA

Product: quaternary ammonium compound-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MYRAPIILKGIFMDWIIIVLAGLFETGWAIGLKYTDGFTRLWPTVGTVFSMVISLALLGIAMKSIPVGTAYAVWVGIGAV
GTAMLGIVLLGEPVNSGRILSLALIIAGIVGLKLTTQS

Sequences:

>Translated_118_residues
MYRAPIILKGIFMDWIIIVLAGLFETGWAIGLKYTDGFTRLWPTVGTVFSMVISLALLGIAMKSIPVGTAYAVWVGIGAV
GTAMLGIVLLGEPVNSGRILSLALIIAGIVGLKLTTQS
>Mature_118_residues
MYRAPIILKGIFMDWIIIVLAGLFETGWAIGLKYTDGFTRLWPTVGTVFSMVISLALLGIAMKSIPVGTAYAVWVGIGAV
GTAMLGIVLLGEPVNSGRILSLALIIAGIVGLKLTTQS

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=105, Percent_Identity=66.6666666666667, Blast_Score=134, Evalue=1e-33,
Organism=Escherichia coli, GI1786755, Length=87, Percent_Identity=37.9310344827586, Blast_Score=66, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12436; Mature: 12436

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRAPIILKGIFMDWIIIVLAGLFETGWAIGLKYTDGFTRLWPTVGTVFSMVISLALLGI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
AMKSIPVGTAYAVWVGIGAVGTAMLGIVLLGEPVNSGRILSLALIIAGIVGLKLTTQS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MYRAPIILKGIFMDWIIIVLAGLFETGWAIGLKYTDGFTRLWPTVGTVFSMVISLALLGI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
AMKSIPVGTAYAVWVGIGAVGTAMLGIVLLGEPVNSGRILSLALIIAGIVGLKLTTQS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]