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The map label for this gene is aes [C]

Identifier: 85859934

GI number: 85859934

Start: 2167807

End: 2169231

Strand: Direct

Name: aes [C]

Synonym: SYN_00679

Alternate gene names: 85859934

Gene position: 2167807-2169231 (Clockwise)

Preceding gene: 85859933

Following gene: 85859935

Centisome position: 68.19

GC content: 59.23

Gene sequence:

>1425_bases
ATGATTCGGGCCTTTTTGATCGCTGCCTTGCTCAGCATCACGGCGCTTGCCGAGGCACAGCCCCTCACGCCACCAACCGA
GGTCGCTGCCGACATTGTCAAGGTTGACCGCTATCCTGCCCACAGCGTTACCTTCCCGAACGGGGTGAAAGGTATTCCGG
GCATGGTCTATTGGGAGCCGGTCGGTTACCGGCCGCTGACGCTCGATCTCTATCTTCCCCCCAGTACCGTCTCGCGACCG
GCGGCTGGATTTCCCCTCGTTCTATACCTCCATGGCGGAGGCTGGATGACAGGGGACACGCACCGGAGCGGGCCTTTTGT
CGATTTCCCCGGCGTCCTGGCTGCGCTGGCAGGCAGGGGCTATGTCGTCGCCGCGATCCAGTATCGCTTAAGCGGTGAGG
CAAAGTTCCCCGCGCAAGCCCAGGATGCGAAAGCGGCCATCCGCTGGCTGCGGCTTCATGCCTCGGAATATGGCATCGAT
CCGGACAAGGCACTGACCTGGGGTATGTCCGCAGGCGGACATCTGGCTGGACTTACTGCGGTCAGTTGCAACGCGGCGGG
GCTTGAACCGAAACAGCCTCATAAATCTTTTCTGCCTGACACAAAGTCCGACCCCATCACCTCATCTCACGTCTCCGATT
GTGTACAGGGTGGCGTCTCCTGGTACGGCGTGTTCAACATGGCGACCATCACAGCCCAGTCGAGACAGGATAAGGCCATG
ACCCGCGATGTGCCCGACGCGCCGGAGTGGCGGCTGCTCGGCTGCTACGGCAGTGCCTGCGGAGAGCAAACCATCGCCGC
GGCAAGCCCGGTCACCTACGTTGACCGCACTGATCCGCCCATGTTGCTGATTGTCGGATCGGAAGACACGGCGGTGCCCT
ACTCTCAAACGCTGGAAATGGCGGATAAGTTGAAGGCGGCCGGCGTGAAGCACGAGCTGATCATACTGCCCGGCGTCAAC
CACGGTTTCATCGGAAATACTCCGGACCAGACACGCGAAGCCAATCTTAAGGCACTCGAGGCTACCTTCAGGTTCATCGA
CAAAACGGCAGGCAAATCCATAGCGACGCAGCCCCCCCTGGAATCAACTCAGACAGGACCACCAGAACCGCCGCCTGTTC
CGGAAGCAATTCAGCCGGAACCATCAGAGTTGCCAAACGGCCCGGAATCCATTCAGGAAGGACCATCGGCAGGGCTGAAG
ATCATTGATGTTCTGCTTGTAAGACCTCTATGCGTGATCGGCTCGACGGTTTCAACAGCGGTCTATGTAGCCCTCTCTCC
CCTGGTTTTCGTCATGGGGGTGGCGGAACCCGCGGCAAGGGTAATGGTCGAGGCTCCCTGGCGATTTACCGCCTTCAGAT
ATATCGGCGAATTCAATCATTATACGGACGAGCAACCCATTATGGGAGTGTGGGATTTCTCATAG

Upstream 100 bases:

>100_bases
TGATTGTTGAGTGGTTTCTTCGGACACGAGGCACCATTAAACGCCTTTAACCATCTATCCAGGGGACAGGTTTGTCAGAT
CCCAGAAAAGGAGAAAAGCC

Downstream 100 bases:

>100_bases
AGCTATGGGAAAATTCATGATGTAATCGCGGCATCGATGCGTCCGGGTTCAGAACGTATTTTTTAGATGTGAGAGAAAAT
GATGAGCTCCCGCCCTGGGA

Product: lipase

Products: alcohol; a carboxylate [C]

Alternate protein names: Alpha/Beta Hydrolase Fold-3 Domain Protein; Esterase/Lipase; Lipase/Esterase; Esterase; Lipase; Esterase/Lipase-Like Protein; Esterase/Lipase/Thioesterase; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Alpha/Beta Hydrolase; Esterase/Lipase/Thioesterase Family Protein; Alpha/Beta Hydrolase Fold Domain Protein; Carboxylesterase Family Protein; Esterase LipC; Esterase/Lipase-Like; Alpha/Beta Hydrolase Fold Protein-3 Domain Protein; Dienelactone Hydrolase; Peptidase; Para-Nitrobenzyl Esterase; Lipoprotein; Membrane-Bound Esterase LipM; Pectinesterase; Triacylglycerol Lipase; Acetyl Esterase; Steroid Monooxygenase; Alpha/Beta Hydrolase Fold Protein; Lipolytic; Membrane-Anchored Peptidase; Esterase-Hydrolase; Alpha/Beta Hydrolase Fold Family Protein; Xylanase; Coagulation Factor 5/8 Type Domain Protein; Lipase/Esterase Protein; Carboxylesterase LipQ; Dipeptidyl Aminopeptidases/Acylaminoacyl-Peptidases-Like; Alpha/Beta Hydrolase Family Protein; Carboxylesterase; Phospholipase/Carboxylesterase; Esterase/Lipase Protein; Lipase LipA; Esterase LipO; Lipase LipH; Esterase LipM; Heroin Esterase

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MIRAFLIAALLSITALAEAQPLTPPTEVAADIVKVDRYPAHSVTFPNGVKGIPGMVYWEPVGYRPLTLDLYLPPSTVSRP
AAGFPLVLYLHGGGWMTGDTHRSGPFVDFPGVLAALAGRGYVVAAIQYRLSGEAKFPAQAQDAKAAIRWLRLHASEYGID
PDKALTWGMSAGGHLAGLTAVSCNAAGLEPKQPHKSFLPDTKSDPITSSHVSDCVQGGVSWYGVFNMATITAQSRQDKAM
TRDVPDAPEWRLLGCYGSACGEQTIAAASPVTYVDRTDPPMLLIVGSEDTAVPYSQTLEMADKLKAAGVKHELIILPGVN
HGFIGNTPDQTREANLKALEATFRFIDKTAGKSIATQPPLESTQTGPPEPPPVPEAIQPEPSELPNGPESIQEGPSAGLK
IIDVLLVRPLCVIGSTVSTAVYVALSPLVFVMGVAEPAARVMVEAPWRFTAFRYIGEFNHYTDEQPIMGVWDFS

Sequences:

>Translated_474_residues
MIRAFLIAALLSITALAEAQPLTPPTEVAADIVKVDRYPAHSVTFPNGVKGIPGMVYWEPVGYRPLTLDLYLPPSTVSRP
AAGFPLVLYLHGGGWMTGDTHRSGPFVDFPGVLAALAGRGYVVAAIQYRLSGEAKFPAQAQDAKAAIRWLRLHASEYGID
PDKALTWGMSAGGHLAGLTAVSCNAAGLEPKQPHKSFLPDTKSDPITSSHVSDCVQGGVSWYGVFNMATITAQSRQDKAM
TRDVPDAPEWRLLGCYGSACGEQTIAAASPVTYVDRTDPPMLLIVGSEDTAVPYSQTLEMADKLKAAGVKHELIILPGVN
HGFIGNTPDQTREANLKALEATFRFIDKTAGKSIATQPPLESTQTGPPEPPPVPEAIQPEPSELPNGPESIQEGPSAGLK
IIDVLLVRPLCVIGSTVSTAVYVALSPLVFVMGVAEPAARVMVEAPWRFTAFRYIGEFNHYTDEQPIMGVWDFS
>Mature_474_residues
MIRAFLIAALLSITALAEAQPLTPPTEVAADIVKVDRYPAHSVTFPNGVKGIPGMVYWEPVGYRPLTLDLYLPPSTVSRP
AAGFPLVLYLHGGGWMTGDTHRSGPFVDFPGVLAALAGRGYVVAAIQYRLSGEAKFPAQAQDAKAAIRWLRLHASEYGID
PDKALTWGMSAGGHLAGLTAVSCNAAGLEPKQPHKSFLPDTKSDPITSSHVSDCVQGGVSWYGVFNMATITAQSRQDKAM
TRDVPDAPEWRLLGCYGSACGEQTIAAASPVTYVDRTDPPMLLIVGSEDTAVPYSQTLEMADKLKAAGVKHELIILPGVN
HGFIGNTPDQTREANLKALEATFRFIDKTAGKSIATQPPLESTQTGPPEPPPVPEAIQPEPSELPNGPESIQEGPSAGLK
IIDVLLVRPLCVIGSTVSTAVYVALSPLVFVMGVAEPAARVMVEAPWRFTAFRYIGEFNHYTDEQPIMGVWDFS

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 50695; Mature: 50695

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRAFLIAALLSITALAEAQPLTPPTEVAADIVKVDRYPAHSVTFPNGVKGIPGMVYWEP
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECC
VGYRPLTLDLYLPPSTVSRPAAGFPLVLYLHGGGWMTGDTHRSGPFVDFPGVLAALAGRG
CCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCHHHHHHHCCCC
YVVAAIQYRLSGEAKFPAQAQDAKAAIRWLRLHASEYGIDPDKALTWGMSAGGHLAGLTA
EEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCEEEEEE
VSCNAAGLEPKQPHKSFLPDTKSDPITSSHVSDCVQGGVSWYGVFNMATITAQSRQDKAM
EECCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEEEEECCHHHHHH
TRDVPDAPEWRLLGCYGSACGEQTIAAASPVTYVDRTDPPMLLIVGSEDTAVPYSQTLEM
HCCCCCCCCEEEEEEECCCCCCCHHHCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHH
ADKLKAAGVKHELIILPGVNHGFIGNTPDQTREANLKALEATFRFIDKTAGKSIATQPPL
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ESTQTGPPEPPPVPEAIQPEPSELPNGPESIQEGPSAGLKIIDVLLVRPLCVIGSTVSTA
CCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHH
VYVALSPLVFVMGVAEPAARVMVEAPWRFTAFRYIGEFNHYTDEQPIMGVWDFS
HHHHHHHHHHHHHCCCCHHHEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCC
>Mature Secondary Structure
MIRAFLIAALLSITALAEAQPLTPPTEVAADIVKVDRYPAHSVTFPNGVKGIPGMVYWEP
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECC
VGYRPLTLDLYLPPSTVSRPAAGFPLVLYLHGGGWMTGDTHRSGPFVDFPGVLAALAGRG
CCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCHHHHHHHCCCC
YVVAAIQYRLSGEAKFPAQAQDAKAAIRWLRLHASEYGIDPDKALTWGMSAGGHLAGLTA
EEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCEEEEEE
VSCNAAGLEPKQPHKSFLPDTKSDPITSSHVSDCVQGGVSWYGVFNMATITAQSRQDKAM
EECCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEEEEECCHHHHHH
TRDVPDAPEWRLLGCYGSACGEQTIAAASPVTYVDRTDPPMLLIVGSEDTAVPYSQTLEM
HCCCCCCCCEEEEEEECCCCCCCHHHCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHH
ADKLKAAGVKHELIILPGVNHGFIGNTPDQTREANLKALEATFRFIDKTAGKSIATQPPL
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ESTQTGPPEPPPVPEAIQPEPSELPNGPESIQEGPSAGLKIIDVLLVRPLCVIGSTVSTA
CCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHH
VYVALSPLVFVMGVAEPAARVMVEAPWRFTAFRYIGEFNHYTDEQPIMGVWDFS
HHHHHHHHHHHHHCCCCHHHEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA