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The map label for this gene is hrb [H]

Identifier: 85859673

GI number: 85859673

Start: 1904950

End: 1905429

Strand: Direct

Name: hrb [H]

Synonym: SYN_02764

Alternate gene names: 85859673

Gene position: 1904950-1905429 (Clockwise)

Preceding gene: 85859672

Following gene: 85859674

Centisome position: 59.92

GC content: 46.46

Gene sequence:

>480_bases
ATGGAAAAATCATGGCAGGATGTGCTCGACAGGTTTCATTATGGGATTTACCTGATCACAGTTTCATCAAAAGAAGGATA
TAACGGCATGATTGTCTCCTGGGTAACCCAATGTTCTCACGAACCGCCTCTCATTGCCGTGTCGATCAGGAAAAACCGTC
TCTCTCATGAACAGATTCTGAAATCAGGGATATACTGCCTTAATGTCCTGCCGAAGGAATCCATCGCTGTAATCAAACAG
TTCAAGATTGCAGACTGGAAGAAAAAATTCGATGCAGTCCGATACAACCCGTCGCAGAACGGTCTTCCCGTACTTGACGA
CTGTATTGGATATCTGGACTGTACTCTGGAAAAGACAATAGATACGGGCGATCACACCCTCTTTGTCGGGAAAACCATCG
GGGGAGCCGTCATTAACGGGGACAAAACGATGACCCTGTCCACACGGGACTATCAGGGCATATATCGGGGAACTCAATAA

Upstream 100 bases:

>100_bases
ATTGAAGAAACTCCATCTCAAAATATAATGAATAGTCAGAGAGATACAACCGGTACTTAAAGCTTTATATGGAAACAACT
TCTTAGAATCCGAGGCGATT

Downstream 100 bases:

>100_bases
CCCCCTCTCATTCCGCACCAGGAAATTCATTTCAGGGTAAATCCACTTTTCCATGGATGATGCCGGATTACGCAGACGAT
TGATGTTTTGTGCTTCCTTC

Product: NAD(P)H-flavin oxidoreductase

Products: NA

Alternate protein names: Nitric oxide reductase NADH:FprA oxidoreductase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MEKSWQDVLDRFHYGIYLITVSSKEGYNGMIVSWVTQCSHEPPLIAVSIRKNRLSHEQILKSGIYCLNVLPKESIAVIKQ
FKIADWKKKFDAVRYNPSQNGLPVLDDCIGYLDCTLEKTIDTGDHTLFVGKTIGGAVINGDKTMTLSTRDYQGIYRGTQ

Sequences:

>Translated_159_residues
MEKSWQDVLDRFHYGIYLITVSSKEGYNGMIVSWVTQCSHEPPLIAVSIRKNRLSHEQILKSGIYCLNVLPKESIAVIKQ
FKIADWKKKFDAVRYNPSQNGLPVLDDCIGYLDCTLEKTIDTGDHTLFVGKTIGGAVINGDKTMTLSTRDYQGIYRGTQ
>Mature_159_residues
MEKSWQDVLDRFHYGIYLITVSSKEGYNGMIVSWVTQCSHEPPLIAVSIRKNRLSHEQILKSGIYCLNVLPKESIAVIKQ
FKIADWKKKFDAVRYNPSQNGLPVLDDCIGYLDCTLEKTIDTGDHTLFVGKTIGGAVINGDKTMTLSTRDYQGIYRGTQ

Specific function: Has nitric oxide reductase activity in combination with FprA; probably involved in nitrosative stress protection. Acts as an NADH:FprA oxidoreductase [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rubredoxin-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR004039
- InterPro:   IPR018527
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct; PF00301 Rubredoxin [H]

EC number: NA

Molecular weight: Translated: 17963; Mature: 17963

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSWQDVLDRFHYGIYLITVSSKEGYNGMIVSWVTQCSHEPPLIAVSIRKNRLSHEQIL
CCCCHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHCCCCCCEEEEEECCCCCCHHHHH
KSGIYCLNVLPKESIAVIKQFKIADWKKKFDAVRYNPSQNGLPVLDDCIGYLDCTLEKTI
HCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHCC
DTGDHTLFVGKTIGGAVINGDKTMTLSTRDYQGIYRGTQ
CCCCCEEEEECCCCCEEECCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MEKSWQDVLDRFHYGIYLITVSSKEGYNGMIVSWVTQCSHEPPLIAVSIRKNRLSHEQIL
CCCCHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHCCCCCCEEEEEECCCCCCHHHHH
KSGIYCLNVLPKESIAVIKQFKIADWKKKFDAVRYNPSQNGLPVLDDCIGYLDCTLEKTI
HCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHCC
DTGDHTLFVGKTIGGAVINGDKTMTLSTRDYQGIYRGTQ
CCCCCEEEEECCCCCEEECCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11160086; 12627946 [H]