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The map label for this gene is pbpG [H]

Identifier: 85859619

GI number: 85859619

Start: 1848072

End: 1850135

Strand: Direct

Name: pbpG [H]

Synonym: SYN_01998

Alternate gene names: 85859619

Gene position: 1848072-1850135 (Clockwise)

Preceding gene: 85859618

Following gene: 85859620

Centisome position: 58.13

GC content: 52.23

Gene sequence:

>2064_bases
GTGACTGTAAGAATGCATTTAAAAATAAAAACGACAATGGCCCCGACAGATTTATTTGAAAGCAGCTCTTTTCCGATTTG
TCACAGGCCTCTGATTTCCAGGATGTGGTGTATTTTTTTATTCATGGCGTTTTTCCTGCCTTCGAGTTTTGCATCATCGG
CCGGCGCTCAGGAATTTGCTTCTTATCCTCCCCTGCCGCGGGGTTTTTCTTCCATAAAGGTCTTCGACAACAAAGGGCGT
TATGTTGGCCGGATACTGCCTGAAAAAAGATACTGGGTCTCCATAGACCAGATAAATCCATTTCTGGAGAAGGCCGTGCT
GGCAATTGAAGATTGCCGGTTTTACGAACACTCCGGAATTGATATCCGTGGGATTGCCAGAGCCGTTGTTAAAGATGTCA
CCAAAGGAAAAATCGTCGAAGGCGGCTCGACCATCACCCAGCAACTTATCAAGAATAAATATCTGTCCGCCAGGAAAACC
TTCGACCGGAAAATTCAGGAAGTTTCCCTCGCTCTGGAATATGAAAAAAAATACACGAAGAAACAGATCCTGGAAATGTA
TTTCAATGAAATTTACTACGGCAACGGGGCTTGGGGAATCGCCCAGGCTTCACTTCTTTATTTCGATAAGACTCCCGCAG
ATCTGACTGAAGCCGAATGCGCGCTTCTGGCCGGTGTTCCAAAGGCGCCAAATCGCTATAATCCTTTCTGCGAAGCCTCT
GTGGTCGGAAAACGCAGGAACCTTGTTCTGAAAAGAATGGCGGAACTGAACATGATTACCGCCGGGAAAAAAAGGAGGCT
GGCGGCCGTTCCCATAACGGTTTTCAAGCGAGGAGAAGCGCCTTATTATGTAACTCACATTAAAAATCAACTGATTGAAC
GGTACGGAAAGGAAATTGTCGACAGAGGCGGACTGGAAGTCACCACAGCCATGAATATTGATTTGCAGAGGCAGGCCGAG
CGTTTTCTGCGTGAGGGAATAAAGAAGCTATCCCCGGATCTTCAGGGAGCCCTATTCTGCATGGATCCGAACACCGGGGA
TGTTCTTGCCGCTGTGGGCGGTGTTGATTTCGCCAAAAGCGCTTATGATCGGGCCTATGTCGCCAGACGCCAGCCCGGCT
CCGCCATCAAACCGTTCATTTACGCGGCCGCCTTGGAAAAAGGATATACGGCCTCCAGCATCCTGAACGACAGGCCGGCA
ACTTACAGCCGGGGGGGGCGGGATAGCTGGACGCCCCGGAATTATGAAGGAACAACACAGGGGGAACTTACTGTTCGACA
GGCCCTTGCTCACTCCAACAATGTGATTGCCGTTAAATTGCTCGATGCCATCGGCGTCCCCTATTTCGTGAATTTCGCCG
GCAGGCAGGGGCTTGCGCTGCGTGCGCAAAACGACCTGTCCCTGGCTCTGGGAACGGAGGAAGTGACCCTTGCCAGTCTT
GTCCAGGCCTACACACCGCTGACCAATGGCGGGTTACGGGCCGAAGCACGGACCATCACCCACGTCTATGACCGGTATTA
TCGTACTTGGACGGAAAATCCCCCGGTTGTCGTCACGCCGGTACTTTTTCCAGCCACCGCCTATGTTGTCACCTCGATGC
TGAAAGACGTCCTGAATTACGGGACGGCCAAGACGCTGAAGCGATTCAGCGGAGAACGCCCCTCCGCGGGAAAGACAGGC
ACGACCGACAACTATCAGGATGCCTGGTTCATTGGCTATACGCCTCAACTCATAACCGGCATCTGGGCAGGCTATGACAA
GCCTAAACCAGGAGGGAAAGGTTTTACCGGGGGGGCAGTCTGCGCTCCGATCTGGGAACGATTCATGCGATCCGCATTAT
CCGGCAAACCAGTTGTTGATTTCCCGAAACCGGAATCGGTCGTTTCCGTTTCCGTCGACCCCATGACGGGCTTCCTGGCA
ACTCCCGACTGCCCGGAACAACGGGAAGAATTCTACCTGCCCGGCACCCAGCCGGTGGATTACTGTCCCATGCATGGCGG
CGAGTCTATTCTTCCGCTGACTCCAGTAGAGACGCTGCCCATGGAACAGGAAAATGCGGAATAA

Upstream 100 bases:

>100_bases
TGCCCCTTTTGACTGGCATTAAGTAATTTCGATCATTCTCCTCTCGAGTATCCCGTAAAGAAAATTTCATGGTTTTGAAA
ATGATCATCAATAAGGAAGT

Downstream 100 bases:

>100_bases
AAAGTGCGGTGGGGAAAAGCAAGTCTTTACGCAAAGGAATATTCTACGATCTCGACGTAATATAAAGATCTTTCAAACCG
ACTGCTCTGAACTGTGCTGA

Product: multimodular transpeptidase-transglycosylase

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MTVRMHLKIKTTMAPTDLFESSSFPICHRPLISRMWCIFLFMAFFLPSSFASSAGAQEFASYPPLPRGFSSIKVFDNKGR
YVGRILPEKRYWVSIDQINPFLEKAVLAIEDCRFYEHSGIDIRGIARAVVKDVTKGKIVEGGSTITQQLIKNKYLSARKT
FDRKIQEVSLALEYEKKYTKKQILEMYFNEIYYGNGAWGIAQASLLYFDKTPADLTEAECALLAGVPKAPNRYNPFCEAS
VVGKRRNLVLKRMAELNMITAGKKRRLAAVPITVFKRGEAPYYVTHIKNQLIERYGKEIVDRGGLEVTTAMNIDLQRQAE
RFLREGIKKLSPDLQGALFCMDPNTGDVLAAVGGVDFAKSAYDRAYVARRQPGSAIKPFIYAAALEKGYTASSILNDRPA
TYSRGGRDSWTPRNYEGTTQGELTVRQALAHSNNVIAVKLLDAIGVPYFVNFAGRQGLALRAQNDLSLALGTEEVTLASL
VQAYTPLTNGGLRAEARTITHVYDRYYRTWTENPPVVVTPVLFPATAYVVTSMLKDVLNYGTAKTLKRFSGERPSAGKTG
TTDNYQDAWFIGYTPQLITGIWAGYDKPKPGGKGFTGGAVCAPIWERFMRSALSGKPVVDFPKPESVVSVSVDPMTGFLA
TPDCPEQREEFYLPGTQPVDYCPMHGGESILPLTPVETLPMEQENAE

Sequences:

>Translated_687_residues
MTVRMHLKIKTTMAPTDLFESSSFPICHRPLISRMWCIFLFMAFFLPSSFASSAGAQEFASYPPLPRGFSSIKVFDNKGR
YVGRILPEKRYWVSIDQINPFLEKAVLAIEDCRFYEHSGIDIRGIARAVVKDVTKGKIVEGGSTITQQLIKNKYLSARKT
FDRKIQEVSLALEYEKKYTKKQILEMYFNEIYYGNGAWGIAQASLLYFDKTPADLTEAECALLAGVPKAPNRYNPFCEAS
VVGKRRNLVLKRMAELNMITAGKKRRLAAVPITVFKRGEAPYYVTHIKNQLIERYGKEIVDRGGLEVTTAMNIDLQRQAE
RFLREGIKKLSPDLQGALFCMDPNTGDVLAAVGGVDFAKSAYDRAYVARRQPGSAIKPFIYAAALEKGYTASSILNDRPA
TYSRGGRDSWTPRNYEGTTQGELTVRQALAHSNNVIAVKLLDAIGVPYFVNFAGRQGLALRAQNDLSLALGTEEVTLASL
VQAYTPLTNGGLRAEARTITHVYDRYYRTWTENPPVVVTPVLFPATAYVVTSMLKDVLNYGTAKTLKRFSGERPSAGKTG
TTDNYQDAWFIGYTPQLITGIWAGYDKPKPGGKGFTGGAVCAPIWERFMRSALSGKPVVDFPKPESVVSVSVDPMTGFLA
TPDCPEQREEFYLPGTQPVDYCPMHGGESILPLTPVETLPMEQENAE
>Mature_686_residues
TVRMHLKIKTTMAPTDLFESSSFPICHRPLISRMWCIFLFMAFFLPSSFASSAGAQEFASYPPLPRGFSSIKVFDNKGRY
VGRILPEKRYWVSIDQINPFLEKAVLAIEDCRFYEHSGIDIRGIARAVVKDVTKGKIVEGGSTITQQLIKNKYLSARKTF
DRKIQEVSLALEYEKKYTKKQILEMYFNEIYYGNGAWGIAQASLLYFDKTPADLTEAECALLAGVPKAPNRYNPFCEASV
VGKRRNLVLKRMAELNMITAGKKRRLAAVPITVFKRGEAPYYVTHIKNQLIERYGKEIVDRGGLEVTTAMNIDLQRQAER
FLREGIKKLSPDLQGALFCMDPNTGDVLAAVGGVDFAKSAYDRAYVARRQPGSAIKPFIYAAALEKGYTASSILNDRPAT
YSRGGRDSWTPRNYEGTTQGELTVRQALAHSNNVIAVKLLDAIGVPYFVNFAGRQGLALRAQNDLSLALGTEEVTLASLV
QAYTPLTNGGLRAEARTITHVYDRYYRTWTENPPVVVTPVLFPATAYVVTSMLKDVLNYGTAKTLKRFSGERPSAGKTGT
TDNYQDAWFIGYTPQLITGIWAGYDKPKPGGKGFTGGAVCAPIWERFMRSALSGKPVVDFPKPESVVSVSVDPMTGFLAT
PDCPEQREEFYLPGTQPVDYCPMHGGESILPLTPVETLPMEQENAE

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=566, Percent_Identity=31.6254416961131, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1788867, Length=585, Percent_Identity=29.5726495726496, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87082258, Length=264, Percent_Identity=36.7424242424242, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI1789601, Length=165, Percent_Identity=37.5757575757576, Blast_Score=115, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 76345; Mature: 76213

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRMHLKIKTTMAPTDLFESSSFPICHRPLISRMWCIFLFMAFFLPSSFASSAGAQEFA
CEEEEEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHH
SYPPLPRGFSSIKVFDNKGRYVGRILPEKRYWVSIDQINPFLEKAVLAIEDCRFYEHSGI
CCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHCCCC
DIRGIARAVVKDVTKGKIVEGGSTITQQLIKNKYLSARKTFDRKIQEVSLALEYEKKYTK
CHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQILEMYFNEIYYGNGAWGIAQASLLYFDKTPADLTEAECALLAGVPKAPNRYNPFCEAS
HHHHHHHHHHHEECCCCCHHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH
VVGKRRNLVLKRMAELNMITAGKKRRLAAVPITVFKRGEAPYYVTHIKNQLIERYGKEIV
HHHHHHHHHHHHHHHHHHEECCCCCEEEECCEEEEECCCCCEEHHHHHHHHHHHHHHHHH
DRGGLEVTTAMNIDLQRQAERFLREGIKKLSPDLQGALFCMDPNTGDVLAAVGGVDFAKS
HCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCHHHHH
AYDRAYVARRQPGSAIKPFIYAAALEKGYTASSILNDRPATYSRGGRDSWTPRNYEGTTQ
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GELTVRQALAHSNNVIAVKLLDAIGVPYFVNFAGRQGLALRAQNDLSLALGTEEVTLASL
CHHHHHHHHHCCCCEEEEEEHHHHCCCEEEEECCCCCEEEEECCCCEEEECCCHHHHHHH
VQAYTPLTNGGLRAEARTITHVYDRYYRTWTENPPVVVTPVLFPATAYVVTSMLKDVLNY
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHC
GTAKTLKRFSGERPSAGKTGTTDNYQDAWFIGYTPQLITGIWAGYDKPKPGGKGFTGGAV
CHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCHH
CAPIWERFMRSALSGKPVVDFPKPESVVSVSVDPMTGFLATPDCPEQREEFYLPGTQPVD
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHCEECCCCCCCC
YCPMHGGESILPLTPVETLPMEQENAE
CCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVRMHLKIKTTMAPTDLFESSSFPICHRPLISRMWCIFLFMAFFLPSSFASSAGAQEFA
EEEEEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHH
SYPPLPRGFSSIKVFDNKGRYVGRILPEKRYWVSIDQINPFLEKAVLAIEDCRFYEHSGI
CCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHCCCC
DIRGIARAVVKDVTKGKIVEGGSTITQQLIKNKYLSARKTFDRKIQEVSLALEYEKKYTK
CHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQILEMYFNEIYYGNGAWGIAQASLLYFDKTPADLTEAECALLAGVPKAPNRYNPFCEAS
HHHHHHHHHHHEECCCCCHHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH
VVGKRRNLVLKRMAELNMITAGKKRRLAAVPITVFKRGEAPYYVTHIKNQLIERYGKEIV
HHHHHHHHHHHHHHHHHHEECCCCCEEEECCEEEEECCCCCEEHHHHHHHHHHHHHHHHH
DRGGLEVTTAMNIDLQRQAERFLREGIKKLSPDLQGALFCMDPNTGDVLAAVGGVDFAKS
HCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCHHHHH
AYDRAYVARRQPGSAIKPFIYAAALEKGYTASSILNDRPATYSRGGRDSWTPRNYEGTTQ
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GELTVRQALAHSNNVIAVKLLDAIGVPYFVNFAGRQGLALRAQNDLSLALGTEEVTLASL
CHHHHHHHHHCCCCEEEEEEHHHHCCCEEEEECCCCCEEEEECCCCEEEECCCHHHHHHH
VQAYTPLTNGGLRAEARTITHVYDRYYRTWTENPPVVVTPVLFPATAYVVTSMLKDVLNY
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHC
GTAKTLKRFSGERPSAGKTGTTDNYQDAWFIGYTPQLITGIWAGYDKPKPGGKGFTGGAV
CHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCHH
CAPIWERFMRSALSGKPVVDFPKPESVVSVSVDPMTGFLATPDCPEQREEFYLPGTQPVD
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHCEECCCCCCCC
YCPMHGGESILPLTPVETLPMEQENAE
CCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]