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The map label for this gene is coaD

Identifier: 85859443

GI number: 85859443

Start: 1647016

End: 1647513

Strand: Direct

Name: coaD

Synonym: SYN_00909

Alternate gene names: 85859443

Gene position: 1647016-1647513 (Clockwise)

Preceding gene: 85859442

Following gene: 85859444

Centisome position: 51.8

GC content: 44.58

Gene sequence:

>498_bases
ATGAAGAAGATTGCTGTTTACCCCGGTTCTTTCGATCCTATTACGAATGGTCATCTCGATATCATTAAAAGGGGCTTGTC
GATGTTTGACGAGCTTATTGTCCTCATTGCATACAACGCAGCAAAGTCGTCTCTGTTTACTGTTCAGGAACGGATAGAAA
TGATTCAGGAAGCACTCCATGACAGAAAAGGTGTCCGCGTCGACAGTTATGACGGTCTTCTGGTGGATTACGTCCGCAAA
GAAGGGGGAAATGTCATTCTTCGGGGGCTGAGAGCCATGTCAGAGTTCGAATATGAGTTTCAGCTTGCTTTGATGAATCG
TCGCCTGAATCGCAACATTGAAACGGTTTTCCTCATGACAGGCTATAAGTGGTTTTATACAAGCTCGACAATTATCAAAG
AGGCCTCCCGCCTTGGAGGCTCTCCGAAAGGTCTTGTACCGGAGGTGGTTTTCAGAAAAATGCAGGAAAAATATCCACTA
ATGAATAAGGGTAAATGA

Upstream 100 bases:

>100_bases
ATAAAAGAGGATATGGCACTGGATGTGGTCGACGTGAGGAGGTATGGGGATACCCTCCTGACATTTTTGAATATTCAAAA
TAAAGTAGAAAGGGGATGAT

Downstream 100 bases:

>100_bases
TGATTATGAAACTGGCATCAAGAGTATCTATGATAAAACCTTCACCGACGCTGGTCATAACCGCAAAAGCCGGCGCCCTG
CGTGCTGAGGGGCGGGATAT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKKIAVYPGSFDPITNGHLDIIKRGLSMFDELIVLIAYNAAKSSLFTVQERIEMIQEALHDRKGVRVDSYDGLLVDYVRK
EGGNVILRGLRAMSEFEYEFQLALMNRRLNRNIETVFLMTGYKWFYTSSTIIKEASRLGGSPKGLVPEVVFRKMQEKYPL
MNKGK

Sequences:

>Translated_165_residues
MKKIAVYPGSFDPITNGHLDIIKRGLSMFDELIVLIAYNAAKSSLFTVQERIEMIQEALHDRKGVRVDSYDGLLVDYVRK
EGGNVILRGLRAMSEFEYEFQLALMNRRLNRNIETVFLMTGYKWFYTSSTIIKEASRLGGSPKGLVPEVVFRKMQEKYPL
MNKGK
>Mature_165_residues
MKKIAVYPGSFDPITNGHLDIIKRGLSMFDELIVLIAYNAAKSSLFTVQERIEMIQEALHDRKGVRVDSYDGLLVDYVRK
EGGNVILRGLRAMSEFEYEFQLALMNRRLNRNIETVFLMTGYKWFYTSSTIIKEASRLGGSPKGLVPEVVFRKMQEKYPL
MNKGK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=42.6751592356688, Blast_Score=150, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_SYNAS (Q2LTS1)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_461645.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q2LTS1
- SMR:   Q2LTS1
- STRING:   Q2LTS1
- GeneID:   3883151
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00909
- NMPDR:   fig|56780.10.peg.1588
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q2LTS1
- ProtClustDB:   CLSK2775543
- BioCyc:   SACI56780:SYN_00909-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18962; Mature: 18962

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAVYPGSFDPITNGHLDIIKRGLSMFDELIVLIAYNAAKSSLFTVQERIEMIQEALH
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRKGVRVDSYDGLLVDYVRKEGGNVILRGLRAMSEFEYEFQLALMNRRLNRNIETVFLMT
HHCCCEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
GYKWFYTSSTIIKEASRLGGSPKGLVPEVVFRKMQEKYPLMNKGK
CCEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKIAVYPGSFDPITNGHLDIIKRGLSMFDELIVLIAYNAAKSSLFTVQERIEMIQEALH
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRKGVRVDSYDGLLVDYVRKEGGNVILRGLRAMSEFEYEFQLALMNRRLNRNIETVFLMT
HHCCCEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
GYKWFYTSSTIIKEASRLGGSPKGLVPEVVFRKMQEKYPLMNKGK
CCEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA