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The map label for this gene is asd [H]

Identifier: 85859441

GI number: 85859441

Start: 1645429

End: 1646445

Strand: Direct

Name: asd [H]

Synonym: SYN_00911

Alternate gene names: 85859441

Gene position: 1645429-1646445 (Clockwise)

Preceding gene: 85859440

Following gene: 85859442

Centisome position: 51.75

GC content: 50.64

Gene sequence:

>1017_bases
ATGAAGTCATATAATGTAGCCGTAGTCGGAGCAACAGGCGCTGTAGGCAATGAAATGATTCGGGTTCTGGAGGATCGCAA
TTTTCCTGTAAAAGAATTGACTCTTCTGGCGTCGGAAAGATCCTTAGGGGTTGAAATTGATTTTCATGGAAAAGCGATTC
CGGTCAAGGTGCTTGATGAAAATTCCTTTGCCGGCATAGACATCGGGCTTTTTTCAGCGGGGGGCAGCGTCAGTGAACGG
TACGCACCCGTTGCCGCAGCCGCGGGATGCGTGGCTATCGATAATACCAGTGCCTTCCGGATGACGCCGGAGATTCCTCT
GATTGTGCCCGAAGTCAATCCAGAAGCCATTGCTCAGTACCGCAATAAGGGAATTATCGCCAATCCCAACTGCTCGACGA
TTCAGATGGTTGTCGCGCTCAAGCCGATTCACGATGCTGCGCGCATCCGGCGGATTGTTGTGTCCACCTATCAGGCCGTA
TCCGGAACGGGAAAGAAGGCCATTACGGAGCTGGCTGAACAGACCCGGGCTTTGATGAGTTGTCAGGAAATCCAGGTTAA
GGTCTATCCTCATCAGATCGCCTTCAATTGTCTGCCGCACATCGACGTGTTTCTTGACAACGGCTATACCAAGGAAGAGA
TGAAGATGGTCAATGAAACCAAAAAAATCTTCAATGACCCTTCCATTGCGGTGACGGCCACGACAGTCCGGGTTCCCGTT
TTTTACGGCCATTCGGAATCCGTAAATATCGAAACGGAGAAAAAAATTACAGCGGAAGAGGTAAAAAAACTGCTTGCTGC
GGCGCCTGGCGTCAAACTGGTTGATAATCCGAAGGAAAATTCCTATCCCCTGGCGATCTACGCGGCGGGGCAGGACGATA
CCTTTGTCGGTCGTATTCGTGAGGACGAATCGATTCCGAACGGTATCAACATGTGGGTCGTTGCCGATAATATTCGAAAG
GGCGCGGCGACAAACGCCGTTCAAATCGCTGAGGTCCTGATTCGGGATTATCTATGA

Upstream 100 bases:

>100_bases
AGGGTGCCTCAATGAATCTGATCGGTCCGGGGTGTCGGCTGAACGGAATTTTATCAATCATCGATAATGAAATATCGATG
AAATAAGGAGAACCAGATTA

Downstream 100 bases:

>100_bases
GAATCATCGGGGGGCAGGCAAAAGGCAGACGCATTGCTGTCCCCCCGGGATATGCCGTCCGGCCGACATCCGACCGGATC
AAGGAAGCTCTGTTCAATAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKSYNVAVVGATGAVGNEMIRVLEDRNFPVKELTLLASERSLGVEIDFHGKAIPVKVLDENSFAGIDIGLFSAGGSVSER
YAPVAAAAGCVAIDNTSAFRMTPEIPLIVPEVNPEAIAQYRNKGIIANPNCSTIQMVVALKPIHDAARIRRIVVSTYQAV
SGTGKKAITELAEQTRALMSCQEIQVKVYPHQIAFNCLPHIDVFLDNGYTKEEMKMVNETKKIFNDPSIAVTATTVRVPV
FYGHSESVNIETEKKITAEEVKKLLAAAPGVKLVDNPKENSYPLAIYAAGQDDTFVGRIREDESIPNGINMWVVADNIRK
GAATNAVQIAEVLIRDYL

Sequences:

>Translated_338_residues
MKSYNVAVVGATGAVGNEMIRVLEDRNFPVKELTLLASERSLGVEIDFHGKAIPVKVLDENSFAGIDIGLFSAGGSVSER
YAPVAAAAGCVAIDNTSAFRMTPEIPLIVPEVNPEAIAQYRNKGIIANPNCSTIQMVVALKPIHDAARIRRIVVSTYQAV
SGTGKKAITELAEQTRALMSCQEIQVKVYPHQIAFNCLPHIDVFLDNGYTKEEMKMVNETKKIFNDPSIAVTATTVRVPV
FYGHSESVNIETEKKITAEEVKKLLAAAPGVKLVDNPKENSYPLAIYAAGQDDTFVGRIREDESIPNGINMWVVADNIRK
GAATNAVQIAEVLIRDYL
>Mature_338_residues
MKSYNVAVVGATGAVGNEMIRVLEDRNFPVKELTLLASERSLGVEIDFHGKAIPVKVLDENSFAGIDIGLFSAGGSVSER
YAPVAAAAGCVAIDNTSAFRMTPEIPLIVPEVNPEAIAQYRNKGIIANPNCSTIQMVVALKPIHDAARIRRIVVSTYQAV
SGTGKKAITELAEQTRALMSCQEIQVKVYPHQIAFNCLPHIDVFLDNGYTKEEMKMVNETKKIFNDPSIAVTATTVRVPV
FYGHSESVNIETEKKITAEEVKKLLAAAPGVKLVDNPKENSYPLAIYAAGQDDTFVGRIREDESIPNGINMWVVADNIRK
GAATNAVQIAEVLIRDYL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=339, Percent_Identity=36.8731563421829, Blast_Score=234, Evalue=4e-63,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=27.8089887640449, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36730; Mature: 36730

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSYNVAVVGATGAVGNEMIRVLEDRNFPVKELTLLASERSLGVEIDFHGKAIPVKVLDE
CCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHEEEECCCCCEEEEEECCCEEEEEEECC
NSFAGIDIGLFSAGGSVSERYAPVAAAAGCVAIDNTSAFRMTPEIPLIVPEVNPEAIAQY
CCCCEEEEEEEECCCCCCHHHCCHHHHCCEEEECCCCEEEECCCCCEEEECCCHHHHHHH
RNKGIIANPNCSTIQMVVALKPIHDAARIRRIVVSTYQAVSGTGKKAITELAEQTRALMS
HCCCEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
CQEIQVKVYPHQIAFNCLPHIDVFLDNGYTKEEMKMVNETKKIFNDPSIAVTATTVRVPV
HEEEEEEEECCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
FYGHSESVNIETEKKITAEEVKKLLAAAPGVKLVDNPKENSYPLAIYAAGQDDTFVGRIR
EECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCCCEEEEEE
EDESIPNGINMWVVADNIRKGAATNAVQIAEVLIRDYL
CCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKSYNVAVVGATGAVGNEMIRVLEDRNFPVKELTLLASERSLGVEIDFHGKAIPVKVLDE
CCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHEEEECCCCCEEEEEECCCEEEEEEECC
NSFAGIDIGLFSAGGSVSERYAPVAAAAGCVAIDNTSAFRMTPEIPLIVPEVNPEAIAQY
CCCCEEEEEEEECCCCCCHHHCCHHHHCCEEEECCCCEEEECCCCCEEEECCCHHHHHHH
RNKGIIANPNCSTIQMVVALKPIHDAARIRRIVVSTYQAVSGTGKKAITELAEQTRALMS
HCCCEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
CQEIQVKVYPHQIAFNCLPHIDVFLDNGYTKEEMKMVNETKKIFNDPSIAVTATTVRVPV
HEEEEEEEECCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
FYGHSESVNIETEKKITAEEVKKLLAAAPGVKLVDNPKENSYPLAIYAAGQDDTFVGRIR
EECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCEEEEECCCCCCEEEEEE
EDESIPNGINMWVVADNIRKGAATNAVQIAEVLIRDYL
CCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]