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The map label for this gene is trpS [H]

Identifier: 85859157

GI number: 85859157

Start: 1332129

End: 1333154

Strand: Direct

Name: trpS [H]

Synonym: SYN_02857

Alternate gene names: 85859157

Gene position: 1332129-1333154 (Clockwise)

Preceding gene: 85859156

Following gene: 85859158

Centisome position: 41.9

GC content: 56.24

Gene sequence:

>1026_bases
TTGATAAAGGACGGAAAAATTTTTCAGGGGGGCATCTTGACAGCGAAACGAATTTTAAGCGGAATGAGGCCCACGGGGAA
ACTCCACCTGGGCAACCTGCACGGTGCGTTGAAAAACTGGGTTGACCTTCAGAATCAAGGTACGTATGAGTGCTTCTACT
TCGTAGCAGACTGGCACGCCTTGACAAGTGACTACAGCAGCACGGATTCGATCCGGGAGAACATCATCGACATGGTGATC
GACTGGCTGAGCGTCGGGCTTGACCCGCGGAAAAGCACCCTGTTCGTCCAGTCGAAAATCAGGGAACACGCGGAGCTTTT
CCTCCTGCTGTCCATGATCACCCCGCTGGCCTGGCTGGAACGGAACCCGACCTATAAGGAGATGAAAGAGGAGCTGACCA
ACCGGGATCTGTCGACTTTCGGTTTCCTGGGCTACCCCGTGCTTCAGGCGGCGGACATCATCATGTACAAGGCCCATGGC
GTGCCCGTGGGGGTGGATCAGTTGCCCCATGTGGAGCTGACGCGGGAAATCACCCGGCGCTTCAATTTTCTCTACCGGGA
AATCTTTCCCATTCCCGAGCCCCTGCTGACCAATGTCCCCAAACTCCTGGGCATCGACGGCAGGAAAATGAGCAAATCCT
ACGACAACTCCATCTTCATCAGCGATCGCGGCGATGCCCTGAACAGGAAGATCATGGCGATGTTCACCGATCCGCAGCGC
ATGCGAAAGACCGATCCGGGGCGGCCTGAGCTTTGCAATGTCTTCAGCTTTCACGGGCTTTACTCTGAAGAAGCCGCCGT
CGGGGAAATCGAAGTGGAGTGCCGCAGGGCGGGAATCGGCTGCATTGAATGCAAGAAGCGCCTGGCGGCCCGTATCGCCG
GGGAGCTGAAAACCGTTCATGAACGGCAGGACTACTATCGCAGTCATATGGATGAGGTTCGGGGAATCATCGATGACGGC
AATGCCCGCGCCCTGAAAATCGCCCGCGCGACCATGGAAGAAGTCCGGGAAGCGGTAAAAATCTGA

Upstream 100 bases:

>100_bases
GTCGGAAAAAATCAAATAAATTTTCTGTTGCGTTTTTCGAGTCTGGAGAAAGCCCCCGGAAGAATAATTTCGGGGGCTTT
CTTGCGTTTACCGGTTATCT

Downstream 100 bases:

>100_bases
TTTCAATCCCGGCTCTGCGATGAGTGAAAGGCAGCGGAATCGATGCAGGCGGACGCAAGGCGATCTTGTGGAACCGGCGT
CGGGCAGAAAGCGAAGAACG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MIKDGKIFQGGILTAKRILSGMRPTGKLHLGNLHGALKNWVDLQNQGTYECFYFVADWHALTSDYSSTDSIRENIIDMVI
DWLSVGLDPRKSTLFVQSKIREHAELFLLLSMITPLAWLERNPTYKEMKEELTNRDLSTFGFLGYPVLQAADIIMYKAHG
VPVGVDQLPHVELTREITRRFNFLYREIFPIPEPLLTNVPKLLGIDGRKMSKSYDNSIFISDRGDALNRKIMAMFTDPQR
MRKTDPGRPELCNVFSFHGLYSEEAAVGEIEVECRRAGIGCIECKKRLAARIAGELKTVHERQDYYRSHMDEVRGIIDDG
NARALKIARATMEEVREAVKI

Sequences:

>Translated_341_residues
MIKDGKIFQGGILTAKRILSGMRPTGKLHLGNLHGALKNWVDLQNQGTYECFYFVADWHALTSDYSSTDSIRENIIDMVI
DWLSVGLDPRKSTLFVQSKIREHAELFLLLSMITPLAWLERNPTYKEMKEELTNRDLSTFGFLGYPVLQAADIIMYKAHG
VPVGVDQLPHVELTREITRRFNFLYREIFPIPEPLLTNVPKLLGIDGRKMSKSYDNSIFISDRGDALNRKIMAMFTDPQR
MRKTDPGRPELCNVFSFHGLYSEEAAVGEIEVECRRAGIGCIECKKRLAARIAGELKTVHERQDYYRSHMDEVRGIIDDG
NARALKIARATMEEVREAVKI
>Mature_341_residues
MIKDGKIFQGGILTAKRILSGMRPTGKLHLGNLHGALKNWVDLQNQGTYECFYFVADWHALTSDYSSTDSIRENIIDMVI
DWLSVGLDPRKSTLFVQSKIREHAELFLLLSMITPLAWLERNPTYKEMKEELTNRDLSTFGFLGYPVLQAADIIMYKAHG
VPVGVDQLPHVELTREITRRFNFLYREIFPIPEPLLTNVPKLLGIDGRKMSKSYDNSIFISDRGDALNRKIMAMFTDPQR
MRKTDPGRPELCNVFSFHGLYSEEAAVGEIEVECRRAGIGCIECKKRLAARIAGELKTVHERQDYYRSHMDEVRGIIDDG
NARALKIARATMEEVREAVKI

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=336, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI41352700, Length=184, Percent_Identity=40.7608695652174, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1789786, Length=337, Percent_Identity=32.9376854599407, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71982800, Length=330, Percent_Identity=29.0909090909091, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=29.0909090909091, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320474, Length=277, Percent_Identity=35.3790613718412, Blast_Score=146, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24666151, Length=330, Percent_Identity=32.7272727272727, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38942; Mature: 38942

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDGKIFQGGILTAKRILSGMRPTGKLHLGNLHGALKNWVDLQNQGTYECFYFVADWHA
CCCCCCEECCHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHCCCCCEEEEEEEEHHHH
LTSDYSSTDSIRENIIDMVIDWLSVGLDPRKSTLFVQSKIREHAELFLLLSMITPLAWLE
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RNPTYKEMKEELTNRDLSTFGFLGYPVLQAADIIMYKAHGVPVGVDQLPHVELTREITRR
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHH
FNFLYREIFPIPEPLLTNVPKLLGIDGRKMSKSYDNSIFISDRGDALNRKIMAMFTDPQR
HHHHHHHHCCCCCHHHHCCHHHHCCCCHHHHHCCCCEEEEECCCCHHCCEEEEEECCHHH
MRKTDPGRPELCNVFSFHGLYSEEAAVGEIEVECRRAGIGCIECKKRLAARIAGELKTVH
HHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ERQDYYRSHMDEVRGIIDDGNARALKIARATMEEVREAVKI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKDGKIFQGGILTAKRILSGMRPTGKLHLGNLHGALKNWVDLQNQGTYECFYFVADWHA
CCCCCCEECCHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHCCCCCEEEEEEEEHHHH
LTSDYSSTDSIRENIIDMVIDWLSVGLDPRKSTLFVQSKIREHAELFLLLSMITPLAWLE
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RNPTYKEMKEELTNRDLSTFGFLGYPVLQAADIIMYKAHGVPVGVDQLPHVELTREITRR
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHH
FNFLYREIFPIPEPLLTNVPKLLGIDGRKMSKSYDNSIFISDRGDALNRKIMAMFTDPQR
HHHHHHHHCCCCCHHHHCCHHHHCCCCHHHHHCCCCEEEEECCCCHHCCEEEEEECCHHH
MRKTDPGRPELCNVFSFHGLYSEEAAVGEIEVECRRAGIGCIECKKRLAARIAGELKTVH
HHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ERQDYYRSHMDEVRGIIDDGNARALKIARATMEEVREAVKI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]