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The map label for this gene is 85858981

Identifier: 85858981

GI number: 85858981

Start: 1162500

End: 1163246

Strand: Direct

Name: 85858981

Synonym: SYN_01017

Alternate gene names: NA

Gene position: 1162500-1163246 (Clockwise)

Preceding gene: 85858980

Following gene: 85858989

Centisome position: 36.56

GC content: 50.87

Gene sequence:

>747_bases
ATGAAAGTCATTTATCATGACGACTTCTGTCAATCGTACACCAGTGATCCGGCCGCCGCTCATGGCCGGATGGAAGCCAT
TGTAAATGCGATTCAGGATCGGGTCGAGTTTGTCAAAGCCAGACCCGCCGAGGAATCGGATATTTCCGCGGTACACACGC
CTTCGCACATCGCTCTGGTTGAAAGGGAAGGCCTTTATGAAATTGCCTCGCTTGCCGCGGGAGGGGCAATTCAGGCCGCT
CAGATCGGGATGAACGAGCCCGCCTTCGCATTGATCCGACCTCCGGGCCATCATGCATCCGCAGGCAGCGCCTGGGGATT
CTGCTATTTCAACAATATGGCCATCGCTCTGGAAAAATTGAAAAGGGAAGGGTGGATTGTCAAGGCATTTATCCTGGATT
TTGATCTCCATTTCGGTGATGGCACGGTAAATATTCTGGAACGGAAAGGGTATGTGACGATTTATAATCCATCGGCGCAC
GATCGAAATGAATATCTTCGAAATATCGAAAAACACCTGTCTTCGGAGTCATTTGATATTCTTGGTGTTTCCGCTGGGTT
CGATAATCATGAAGAGGACTGGGGCGGACTGTTGACGACGGAGGATTACAGAGTCATTGGGAAAATGGTCTGTGAGGCCT
GCCAGAAATATCGATGCGGAACTTTCGCCGTTCTTGAAGGAGGGTATAATCATCGGGTGCTGGGCCGGAACGTACTGGCT
TTTCTGGAGGGACTCGAGGGACGGTAA

Upstream 100 bases:

>100_bases
AAGTCAGATTGGGCATCTCTTCGATGTCCGAGGTTTTATAAATTGATGCCATTGTCAGCCAGCCGTAACAGAAGGATCTT
TTACGGGAGGTGTCGAAATC

Downstream 100 bases:

>100_bases
GAAAAACGTTTCAGTGAAACGTGTCCGGATTTTCACTTTCCAATGCAGAATGACGAAAAGATGCGATCCAGGATATCTTC
CGTCACGGTTTCTCCCGCAA

Product: deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKVIYHDDFCQSYTSDPAAAHGRMEAIVNAIQDRVEFVKARPAEESDISAVHTPSHIALVEREGLYEIASLAAGGAIQAA
QIGMNEPAFALIRPPGHHASAGSAWGFCYFNNMAIALEKLKREGWIVKAFILDFDLHFGDGTVNILERKGYVTIYNPSAH
DRNEYLRNIEKHLSSESFDILGVSAGFDNHEEDWGGLLTTEDYRVIGKMVCEACQKYRCGTFAVLEGGYNHRVLGRNVLA
FLEGLEGR

Sequences:

>Translated_248_residues
MKVIYHDDFCQSYTSDPAAAHGRMEAIVNAIQDRVEFVKARPAEESDISAVHTPSHIALVEREGLYEIASLAAGGAIQAA
QIGMNEPAFALIRPPGHHASAGSAWGFCYFNNMAIALEKLKREGWIVKAFILDFDLHFGDGTVNILERKGYVTIYNPSAH
DRNEYLRNIEKHLSSESFDILGVSAGFDNHEEDWGGLLTTEDYRVIGKMVCEACQKYRCGTFAVLEGGYNHRVLGRNVLA
FLEGLEGR
>Mature_248_residues
MKVIYHDDFCQSYTSDPAAAHGRMEAIVNAIQDRVEFVKARPAEESDISAVHTPSHIALVEREGLYEIASLAAGGAIQAA
QIGMNEPAFALIRPPGHHASAGSAWGFCYFNNMAIALEKLKREGWIVKAFILDFDLHFGDGTVNILERKGYVTIYNPSAH
DRNEYLRNIEKHLSSESFDILGVSAGFDNHEEDWGGLLTTEDYRVIGKMVCEACQKYRCGTFAVLEGGYNHRVLGRNVLA
FLEGLEGR

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI226529806, Length=189, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI20070354, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI153085395, Length=187, Percent_Identity=26.2032085561497, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI169234807, Length=212, Percent_Identity=25, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI148539870, Length=212, Percent_Identity=25, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI17158039, Length=188, Percent_Identity=27.1276595744681, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI30795204, Length=188, Percent_Identity=27.1276595744681, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI30795202, Length=188, Percent_Identity=27.1276595744681, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI62750349, Length=78, Percent_Identity=41.025641025641, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI62750347, Length=78, Percent_Identity=41.025641025641, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17537347, Length=141, Percent_Identity=35.4609929078014, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17540332, Length=233, Percent_Identity=26.6094420600858, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540334, Length=233, Percent_Identity=26.6094420600858, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193206283, Length=233, Percent_Identity=26.6094420600858, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193209491, Length=226, Percent_Identity=30.5309734513274, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25154020, Length=286, Percent_Identity=24.8251748251748, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25154022, Length=286, Percent_Identity=25.8741258741259, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324307, Length=142, Percent_Identity=32.3943661971831, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281360899, Length=178, Percent_Identity=27.5280898876405, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24642146, Length=178, Percent_Identity=27.5280898876405, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24642144, Length=178, Percent_Identity=27.5280898876405, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24642142, Length=178, Percent_Identity=27.5280898876405, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281360801, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281360799, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641720, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 27481; Mature: 27481

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIYHDDFCQSYTSDPAAAHGRMEAIVNAIQDRVEFVKARPAEESDISAVHTPSHIALV
CEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEE
EREGLYEIASLAAGGAIQAAQIGMNEPAFALIRPPGHHASAGSAWGFCYFNNMAIALEKL
ECCCHHHHHHHHCCCCEEHHHCCCCCCCEEEECCCCCCCCCCCCEEEEEECCHHHHHHHH
KREGWIVKAFILDFDLHFGDGTVNILERKGYVTIYNPSAHDRNEYLRNIEKHLSSESFDI
HHCCCEEEEEEEEEEEEECCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEE
LGVSAGFDNHEEDWGGLLTTEDYRVIGKMVCEACQKYRCGTFAVLEGGYNHRVLGRNVLA
EEEECCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHH
FLEGLEGR
HHHCCCCC
>Mature Secondary Structure
MKVIYHDDFCQSYTSDPAAAHGRMEAIVNAIQDRVEFVKARPAEESDISAVHTPSHIALV
CEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEE
EREGLYEIASLAAGGAIQAAQIGMNEPAFALIRPPGHHASAGSAWGFCYFNNMAIALEKL
ECCCHHHHHHHHCCCCEEHHHCCCCCCCEEEECCCCCCCCCCCCEEEEEECCHHHHHHHH
KREGWIVKAFILDFDLHFGDGTVNILERKGYVTIYNPSAHDRNEYLRNIEKHLSSESFDI
HHCCCEEEEEEEEEEEEECCCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEE
LGVSAGFDNHEEDWGGLLTTEDYRVIGKMVCEACQKYRCGTFAVLEGGYNHRVLGRNVLA
EEEECCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHH
FLEGLEGR
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]