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The map label for this gene is nagB [H]

Identifier: 85858599

GI number: 85858599

Start: 764262

End: 765221

Strand: Direct

Name: nagB [H]

Synonym: SYN_02958

Alternate gene names: 85858599

Gene position: 764262-765221 (Clockwise)

Preceding gene: 85858598

Following gene: 85858600

Centisome position: 24.04

GC content: 54.06

Gene sequence:

>960_bases
ATGTCATTCAAGGTCATCGTCACACGTGATTTCGAACACATGAGCGAGGTCGCCGCCGGGTTGGTCATTGAAAACATCCG
CCAGGTCCTCAAAGAAAAGGATATTTTCAACCTGGGGCTGGCGACGGGAAATTCGCCGACGGGCCTGTATAAGCATCTCG
CTAGGGCGGCTAATGAAGGCAGCTTTGACAGCGGCCGCATCCGGAGCTTCAACCTGGATGAGTATTGCGGCCTTCCCGGC
GAAAATGCCCAGCAGCGGGCCCTCCATCCGGAAAGCTACAGCTTTTTCATGATTCAGGAACTGTTCGGCCTTCTCGACAG
GAAGTTCAAGGAAACATACGTTCCCTGGGGCACCTTGATTGATCAGGGAAGGCTGATTGAGGAGCTTGCGGCGAATCCCG
CAGACTGGAAAGAAGTCGGGGCCGACAAGGGAAAGGCCATCGTCATTGACCTGCAGGCAAAATCCGAATATCTGAGGTGG
GTGCGCAAATCGATTCTGGACGCATACGTAGAAAAGATTTCGGGATATGGCGGGATCGATCTTCATATCATCGGGGTTGG
CGGTCGCGGTCACGTGGCCTTTCATGAATCGGGCATCCCCTTCGAGGGAAACTCGATGCTCCTGGTAAAACTGGATGAAA
ATACCATAGAAAACGCTGTTAAAGACGGCCACTTTGTCAGCCGGAATGACAGCCCTTCCTACGCTGTCTCCATGGGCGCC
GAGCTGGTCTATAAGGCCCGAACCGTCGTTCTTCTGGCGAACGGCGCCCGCAAAACGGAACCCATTGCGGAATCGATTCT
GGACGATCCCAGCCCCCTGGTGCCCATATCTTACGGAAAACATTACGCCAGGCAGGGCGGCCGGATGATTTATGTCCTTG
ATAAAGCCGCGGCGGAAAAGCTTCTCCGGAATGCCGATGCCGTAAAGAAACAGGGAATTGAGCTCGATGATTTAAGCTGA

Upstream 100 bases:

>100_bases
AAGGCCCCACCCAGGAAGAAACCCTCAAATATTGCAAACAGATCGCCGATGTGGTGAAGGAAGAGCTCGGCTGATCCTTT
AGAGAAAGCAGGGAGACAGC

Downstream 100 bases:

>100_bases
AACGAGTGAAGGCAGGCGGAAAGGTAACGCTTTGCCGCCTGCCCTCTGATCCCTTCCGCATATCTCCGTGAGAAATCTGT
AATACAAAAGCAGCACCTGC

Product: 6-phosphogluconolactonase/glucosamine-6- phosphate isomerase/deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSFKVIVTRDFEHMSEVAAGLVIENIRQVLKEKDIFNLGLATGNSPTGLYKHLARAANEGSFDSGRIRSFNLDEYCGLPG
ENAQQRALHPESYSFFMIQELFGLLDRKFKETYVPWGTLIDQGRLIEELAANPADWKEVGADKGKAIVIDLQAKSEYLRW
VRKSILDAYVEKISGYGGIDLHIIGVGGRGHVAFHESGIPFEGNSMLLVKLDENTIENAVKDGHFVSRNDSPSYAVSMGA
ELVYKARTVVLLANGARKTEPIAESILDDPSPLVPISYGKHYARQGGRMIYVLDKAAAEKLLRNADAVKKQGIELDDLS

Sequences:

>Translated_319_residues
MSFKVIVTRDFEHMSEVAAGLVIENIRQVLKEKDIFNLGLATGNSPTGLYKHLARAANEGSFDSGRIRSFNLDEYCGLPG
ENAQQRALHPESYSFFMIQELFGLLDRKFKETYVPWGTLIDQGRLIEELAANPADWKEVGADKGKAIVIDLQAKSEYLRW
VRKSILDAYVEKISGYGGIDLHIIGVGGRGHVAFHESGIPFEGNSMLLVKLDENTIENAVKDGHFVSRNDSPSYAVSMGA
ELVYKARTVVLLANGARKTEPIAESILDDPSPLVPISYGKHYARQGGRMIYVLDKAAAEKLLRNADAVKKQGIELDDLS
>Mature_318_residues
SFKVIVTRDFEHMSEVAAGLVIENIRQVLKEKDIFNLGLATGNSPTGLYKHLARAANEGSFDSGRIRSFNLDEYCGLPGE
NAQQRALHPESYSFFMIQELFGLLDRKFKETYVPWGTLIDQGRLIEELAANPADWKEVGADKGKAIVIDLQAKSEYLRWV
RKSILDAYVEKISGYGGIDLHIIGVGGRGHVAFHESGIPFEGNSMLLVKLDENTIENAVKDGHFVSRNDSPSYAVSMGAE
LVYKARTVVLLANGARKTEPIAESILDDPSPLVPISYGKHYARQGGRMIYVLDKAAAEKLLRNADAVKKQGIELDDLS

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI17554876, Length=275, Percent_Identity=26.9090909090909, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 35258; Mature: 35126

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKVIVTRDFEHMSEVAAGLVIENIRQVLKEKDIFNLGLATGNSPTGLYKHLARAANEG
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCC
SFDSGRIRSFNLDEYCGLPGENAQQRALHPESYSFFMIQELFGLLDRKFKETYVPWGTLI
CCCCCCEEEECCHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
DQGRLIEELAANPADWKEVGADKGKAIVIDLQAKSEYLRWVRKSILDAYVEKISGYGGID
HCCHHHHHHCCCCCCHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCE
LHIIGVGGRGHVAFHESGIPFEGNSMLLVKLDENTIENAVKDGHFVSRNDSPSYAVSMGA
EEEEEECCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHCCCEECCCCCCCEEHHHHH
ELVYKARTVVLLANGARKTEPIAESILDDPSPLVPISYGKHYARQGGRMIYVLDKAAAEK
HHHEEEEEEEEEECCCCCCHHHHHHHHCCCCCEEECCCCHHHHHCCCCEEEEECHHHHHH
LLRNADAVKKQGIELDDLS
HHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SFKVIVTRDFEHMSEVAAGLVIENIRQVLKEKDIFNLGLATGNSPTGLYKHLARAANEG
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCC
SFDSGRIRSFNLDEYCGLPGENAQQRALHPESYSFFMIQELFGLLDRKFKETYVPWGTLI
CCCCCCEEEECCHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
DQGRLIEELAANPADWKEVGADKGKAIVIDLQAKSEYLRWVRKSILDAYVEKISGYGGID
HCCHHHHHHCCCCCCHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCE
LHIIGVGGRGHVAFHESGIPFEGNSMLLVKLDENTIENAVKDGHFVSRNDSPSYAVSMGA
EEEEEECCCCEEEEECCCCCCCCCCEEEEEECCHHHHHHHHCCCEECCCCCCCEEHHHHH
ELVYKARTVVLLANGARKTEPIAESILDDPSPLVPISYGKHYARQGGRMIYVLDKAAAEK
HHHEEEEEEEEEECCCCCCHHHHHHHHCCCCCEEECCCCHHHHHCCCCEEEEECHHHHHH
LLRNADAVKKQGIELDDLS
HHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]