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The map label for this gene is mraY

Identifier: 85858523

GI number: 85858523

Start: 675776

End: 676855

Strand: Direct

Name: mraY

Synonym: SYN_01743

Alternate gene names: 85858523

Gene position: 675776-676855 (Clockwise)

Preceding gene: 85858522

Following gene: 85858524

Centisome position: 21.26

GC content: 53.89

Gene sequence:

>1080_bases
ATGCTTTATCACCTTCTCTATCCACTGCATACAACCTATTCCTATTTTAATGTCTTCCGCTACATCACGTTCCGGACGAT
ATATGCAGCCATTACCGCCCTGATCATCTGTTTCCTGCTGGGCCCCTGGCTGATCCGGAAGCTTCGGGAATTGAAGATGG
GACAGGTCATCCGGGATGACGGCCCTGAAGCGCATCTTTCCAAACAGGGGACGCCGACGATGGGGGGGGTCCTGATTATT
TTCGCCGTCGTCGTTTCGACATTGCTTTGGGCCAATCTCACGATCGATTATGTCTGGCTTGTGCTGATGGTAACTCTGGG
ATACGGACTGATCGGCTTTGCCGACGATTACCGTAAGCTGACGCGTCAGAGTTCCCGGGGAGTCTCCGGAAAGGTTCGGC
TGGCCTGTGAAGTGTGCATCGCTCTTCTCGTCAGCGTTGTCCTTTACGCAAAGCCGGGGTTCAATTCCACCATCGCCATT
CCTTTTTTCAAGACCGTGCTTCCGGATCTGGGGTGGGGATACATTTTTCTTTCCACGTTCATCATCGTCGGGGCCGCGAA
TGCCGTGAATTTAACGGACGGACTGGATGGTCTGGCCATCGGACCGGCCATTACCTGCTTCATGACTTATCTGCTCTTTG
CCTATTTCGCGGGCAATTTCAAGATTGCCTCCTACCTGCAGATTCCCGGTGTGGCCGGCGTCGGAGAATTGAGCATTTTC
TGCGGTGCAATCGTGGGCGCGGGTATCGGTTTCCTCTGGTACAATACCTATCCGGCCCAGGTTTTCATGGGAGATACCGG
GTCCCTCTCTCTCGGCGGCGCCCTTGGCTGTCTGGCCATTGTGACCAAGCAGGAGATTCTGCTGGCCATCGTAGGGGGGA
TTTTCGTGCTGGAAACCTTCTCGGTTATCTTTCAGGTCGGGTGGTTCAAGCTTTCCCACGGGAAGCGCATCTTCCGTATG
GCTCCGATCCATCATCATTTTGAATTGAAGGGATGGGCGGAGCCGAAGGTGATTGTCCGCTTCTGGATCATTTCCATCCT
GCTGGCCCTGCTGGCCATCAGTACACTAAAACTTCGATAG

Upstream 100 bases:

>100_bases
GGGGGACTGGATCCTTGTCAAAGGATCGCGGCTGATGAAAATGGAAGAAATCGTCAAGAAAATTCTTGATCGGACTCCGG
CATAAACGGATTGAAACAGA

Downstream 100 bases:

>100_bases
GATGTTCTTCATGGATATATCAGGACAGAGAATGCTGGTAATCGGCTGGGGAAAAACGGGTGTCGCCTCCGCGCGGTTTC
TGATTTCTCGTGGCGCCCGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MLYHLLYPLHTTYSYFNVFRYITFRTIYAAITALIICFLLGPWLIRKLRELKMGQVIRDDGPEAHLSKQGTPTMGGVLII
FAVVVSTLLWANLTIDYVWLVLMVTLGYGLIGFADDYRKLTRQSSRGVSGKVRLACEVCIALLVSVVLYAKPGFNSTIAI
PFFKTVLPDLGWGYIFLSTFIIVGAANAVNLTDGLDGLAIGPAITCFMTYLLFAYFAGNFKIASYLQIPGVAGVGELSIF
CGAIVGAGIGFLWYNTYPAQVFMGDTGSLSLGGALGCLAIVTKQEILLAIVGGIFVLETFSVIFQVGWFKLSHGKRIFRM
APIHHHFELKGWAEPKVIVRFWIISILLALLAISTLKLR

Sequences:

>Translated_359_residues
MLYHLLYPLHTTYSYFNVFRYITFRTIYAAITALIICFLLGPWLIRKLRELKMGQVIRDDGPEAHLSKQGTPTMGGVLII
FAVVVSTLLWANLTIDYVWLVLMVTLGYGLIGFADDYRKLTRQSSRGVSGKVRLACEVCIALLVSVVLYAKPGFNSTIAI
PFFKTVLPDLGWGYIFLSTFIIVGAANAVNLTDGLDGLAIGPAITCFMTYLLFAYFAGNFKIASYLQIPGVAGVGELSIF
CGAIVGAGIGFLWYNTYPAQVFMGDTGSLSLGGALGCLAIVTKQEILLAIVGGIFVLETFSVIFQVGWFKLSHGKRIFRM
APIHHHFELKGWAEPKVIVRFWIISILLALLAISTLKLR
>Mature_359_residues
MLYHLLYPLHTTYSYFNVFRYITFRTIYAAITALIICFLLGPWLIRKLRELKMGQVIRDDGPEAHLSKQGTPTMGGVLII
FAVVVSTLLWANLTIDYVWLVLMVTLGYGLIGFADDYRKLTRQSSRGVSGKVRLACEVCIALLVSVVLYAKPGFNSTIAI
PFFKTVLPDLGWGYIFLSTFIIVGAANAVNLTDGLDGLAIGPAITCFMTYLLFAYFAGNFKIASYLQIPGVAGVGELSIF
CGAIVGAGIGFLWYNTYPAQVFMGDTGSLSLGGALGCLAIVTKQEILLAIVGGIFVLETFSVIFQVGWFKLSHGKRIFRM
APIHHHFELKGWAEPKVIVRFWIISILLALLAISTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=57.0637119113573, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_SYNAS (Q2LR51)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_460725.1
- STRING:   Q2LR51
- GeneID:   3885150
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_01743
- NMPDR:   fig|56780.10.peg.670
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q2LR51
- ProtClustDB:   PRK00108
- BioCyc:   SACI56780:SYN_01743-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39548; Mature: 39548

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14579060)-; HASH(0x14958c00)-; HASH(0x1426e308)-; HASH(0x142640e8)-; HASH(0x14046e34)-; HASH(0x1478432c)-; HASH(0x14142a34)-; HASH(0x14958b40)-; HASH(0x13fb52cc)-; HASH(0x94acf00)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYHLLYPLHTTYSYFNVFRYITFRTIYAAITALIICFLLGPWLIRKLRELKMGQVIRDD
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPEAHLSKQGTPTMGGVLIIFAVVVSTLLWANLTIDYVWLVLMVTLGYGLIGFADDYRKL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TRQSSRGVSGKVRLACEVCIALLVSVVLYAKPGFNSTIAIPFFKTVLPDLGWGYIFLSTF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCCCHHHHHHHHH
IIVGAANAVNLTDGLDGLAIGPAITCFMTYLLFAYFAGNFKIASYLQIPGVAGVGELSIF
HHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHH
CGAIVGAGIGFLWYNTYPAQVFMGDTGSLSLGGALGCLAIVTKQEILLAIVGGIFVLETF
HHHHHHCCHHHHEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGWFKLSHGKRIFRMAPIHHHFELKGWAEPKVIVRFWIISILLALLAISTLKLR
HHHHHHHHEEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLYHLLYPLHTTYSYFNVFRYITFRTIYAAITALIICFLLGPWLIRKLRELKMGQVIRDD
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPEAHLSKQGTPTMGGVLIIFAVVVSTLLWANLTIDYVWLVLMVTLGYGLIGFADDYRKL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TRQSSRGVSGKVRLACEVCIALLVSVVLYAKPGFNSTIAIPFFKTVLPDLGWGYIFLSTF
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCCCHHHHHHHHH
IIVGAANAVNLTDGLDGLAIGPAITCFMTYLLFAYFAGNFKIASYLQIPGVAGVGELSIF
HHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHH
CGAIVGAGIGFLWYNTYPAQVFMGDTGSLSLGGALGCLAIVTKQEILLAIVGGIFVLETF
HHHHHHCCHHHHEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGWFKLSHGKRIFRMAPIHHHFELKGWAEPKVIVRFWIISILLALLAISTLKLR
HHHHHHHHEEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA