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The map label for this gene is infC [H]

Identifier: 85858498

GI number: 85858498

Start: 654872

End: 655417

Strand: Direct

Name: infC [H]

Synonym: SYN_01718

Alternate gene names: 85858498

Gene position: 654872-655417 (Clockwise)

Preceding gene: 85858497

Following gene: 85858499

Centisome position: 20.6

GC content: 47.44

Gene sequence:

>546_bases
ATGTGGGATTCATCTTACATTTGCAGGAGGTGTCCAATAGTTAAAGATCTGAAGATCAACAATGAGATTAAGGCGGCCAC
TGTAAGAGTTATCAGTTATCAGGGCGAGCAGTTGGGTGTATTGACCCTTGCGGACGCGCTTGCAGAGGCCAGAAAAGAAG
GCTTGGACCTCGTGGAAGTCGCCTCCACTTCCACGCCTCCTGTCTGCCGGATCATGGATTACGGCAAGTTCAGGTATCAA
CAAAGTAAAAAACTTCAGGTTGCCAGAAAAAGTCAGAGTACCATTCAGGTCAAGGAGATTCGACTGAGGCCGAAGGTAGA
GGAACACGATCTTCAAGTCAAGATCAAGCATATCCGGAAGTTTCTCGAACAGCATGACAAGGTCAAGGTCAGTGTCCTGT
TTCGGGGGAGGGAAATCGCGTTCACCGATATAGGGCGAAAGCTTCTTGAAGATATAAAAAACAACCTGGGTGACAGCTGT
AACATAGATCAACAGCCGAAACTGGAAGGGCGGAATATGGTCATGGTTTTGTCGCCCAAAAAGTAG

Upstream 100 bases:

>100_bases
GACCCTGCCGGTTTCTGCCTTTATTGAACTGGTAAAGGAAAAGAGCAGTCAGTATCTGTAATCGGCGCTTGAATCCATCA
TCAGACCCTGTGAAGCGGGG

Downstream 100 bases:

>100_bases
GCGGCAGGAAGATACTTATCGATGTTCTTCCTGATGATGGAACAGGAGAAATCGTTATGCTGATTGTTAATTGTAAAATA
AACGGTTAGTGCGAAGCAGA

Product: translation initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MWDSSYICRRCPIVKDLKINNEIKAATVRVISYQGEQLGVLTLADALAEARKEGLDLVEVASTSTPPVCRIMDYGKFRYQ
QSKKLQVARKSQSTIQVKEIRLRPKVEEHDLQVKIKHIRKFLEQHDKVKVSVLFRGREIAFTDIGRKLLEDIKNNLGDSC
NIDQQPKLEGRNMVMVLSPKK

Sequences:

>Translated_181_residues
MWDSSYICRRCPIVKDLKINNEIKAATVRVISYQGEQLGVLTLADALAEARKEGLDLVEVASTSTPPVCRIMDYGKFRYQ
QSKKLQVARKSQSTIQVKEIRLRPKVEEHDLQVKIKHIRKFLEQHDKVKVSVLFRGREIAFTDIGRKLLEDIKNNLGDSC
NIDQQPKLEGRNMVMVLSPKK
>Mature_181_residues
MWDSSYICRRCPIVKDLKINNEIKAATVRVISYQGEQLGVLTLADALAEARKEGLDLVEVASTSTPPVCRIMDYGKFRYQ
QSKKLQVARKSQSTIQVKEIRLRPKVEEHDLQVKIKHIRKFLEQHDKVKVSVLFRGREIAFTDIGRKLLEDIKNNLGDSC
NIDQQPKLEGRNMVMVLSPKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=174, Percent_Identity=46.551724137931, Blast_Score=158, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20792; Mature: 20792

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDSSYICRRCPIVKDLKINNEIKAATVRVISYQGEQLGVLTLADALAEARKEGLDLVEV
CCCCCCHHHHCCCCEEEECCCCEEEEEEEEEEECCCEEHHHHHHHHHHHHHHCCCCEEEE
ASTSTPPVCRIMDYGKFRYQQSKKLQVARKSQSTIQVKEIRLRPKVEEHDLQVKIKHIRK
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCEEEHHHHHH
FLEQHDKVKVSVLFRGREIAFTDIGRKLLEDIKNNLGDSCNIDQQPKLEGRNMVMVLSPK
HHHHCCCEEEEEEEECCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
K
C
>Mature Secondary Structure
MWDSSYICRRCPIVKDLKINNEIKAATVRVISYQGEQLGVLTLADALAEARKEGLDLVEV
CCCCCCHHHHCCCCEEEECCCCEEEEEEEEEEECCCEEHHHHHHHHHHHHHHCCCCEEEE
ASTSTPPVCRIMDYGKFRYQQSKKLQVARKSQSTIQVKEIRLRPKVEEHDLQVKIKHIRK
CCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCEEEHHHHHH
FLEQHDKVKVSVLFRGREIAFTDIGRKLLEDIKNNLGDSCNIDQQPKLEGRNMVMVLSPK
HHHHCCCEEEEEEEECCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA