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The map label for this gene is atpA1

Identifier: 85858475

GI number: 85858475

Start: 630634

End: 632148

Strand: Direct

Name: atpA1

Synonym: SYN_00546

Alternate gene names: 85858475

Gene position: 630634-632148 (Clockwise)

Preceding gene: 85858474

Following gene: 85858476

Centisome position: 19.84

GC content: 48.98

Gene sequence:

>1515_bases
ATGGATACAATCAAGGCAGAGGAAATAAGTCAAATAATATCCAAGCAAATTCGGGATTATGAGAAGAAGCTTGATGTCAG
TGAAACCGGTACCGTCCTTTCCGTCGGTGACGGCATTGCCAGAATATATGGCGTTGAAAATGCAATGGCCATGGAGCTGC
TGGAGTTTCCTGGCGGTATCATGGGCATGGTGTTGAACCTAGAAGCGGACAACGTTGGTGTTGCCGTCCTTGGGGATGTA
ACCCACATTAAGGAAGGTGACATAGTTAAGAGGACGGGTAAAATCGCACAGATTCCAGTTGGAGAGGCGCTGCTGGGCAG
AGTTATCGATGCGACGGGAGAACCTATTGATGGAAAGGGGCCCCTTGGAGCTACGGAGTTCAGCCGAATAGAGATGATTG
CTCCCGGTGTTATCAAACGTCAGCCCGTTAATGAGCCCATGTACACCGGCCTCAAAGCTATCGATGCCATGACACCGATC
GGCAGAGGTCAGCGTGAACTCATTATTGGAGACCGCCAGATCGGAAAAACGGCCATAGGTATTGACGCAATTATTCGGCA
GAAGGATACCGGTGTGAAGTGCATTTATGTGGCAATTGGTCAAAAGAAATCCACCGTTTCTCAGATTGTTGAAAATCTCA
GGAAACATGACGCAATGTCCTATACCTGTGTTGTGGCCGGATGCGCCAGTGACCCAGCGACATTGCAGTACATCGCTGCA
TATGCCGGATGCAGTATCGGTGAATATTTCAGAGACCGGGGCCAGGATGCCCTGATCATCTATGACGATCTGTCCAAACA
GGCCGTCGCTTACAGACAGATTTCACTGCTTTTAAGACGACCGCCGGGACGGGAGGCATATCCGGGGGACATTTTCTATA
ATCACTCCAGGCTGCTGGAAAGATCAGCGCGTGTCAGTGCAGATCTGGGTGGTGGCTCGCTGACGGCATTGCCGATTATC
GAAACACAGGCCGGTGATGTTTCAGCGTATATTCCGACAAATGTTATTTCGATTACGGATGGCCAGGTTTATTTGGAGCC
GAGCCTTTTCTTCTCAGGTATTCGCCCGGCAATTAATGTGGGCCTTTCCGTATCCCGCGTAGGTGGCGCGGCCCAGGTCA
AGGCTATGAAGCAGGTTGCTGGCACGCTGAAACTGGATTTGGCTCAGTATCGTGAACTTGCATCATTTGCTCAGTTCGGA
AGCGACTTGGATAAAGCGACACAGGCTCAGCTTGATCGTGGTGTGCGGTTGGTAGAAATTTTGAAGCAACCTCAGTTCCA
GCCGATGAGTCTGGCGGAAGAAGTCATTGTTTTATTCGCAGGAACGCGAGGATTTCTTGATAAGTATGAAGTTGAAAAAA
TAAAGGAGTATGAACCGCAGGTTCTGGCATATATGAAAAGTAAACACCAGGATATTATGCAGGAAATAGATGATAAGAAG
GTCATTTCGCCAGAATTGGAACAGAAGATTAAGGAAGCGCTGACGGCGTTTGATTCAGTGTTTGTTGCAGGGTAG

Upstream 100 bases:

>100_bases
GGGTGGTATTGTCATCAGAGTAGGGGATACGCTTTATGATGGAAGCATAAAGACTCAGTTGAGTAATATAAGGAATCTCT
TAGGGGAGGCAGTATAGACC

Downstream 100 bases:

>100_bases
GAGACTATAATAACCTGTGAGCTGGTAGTGAGATTAAGAGGGAAAAGTCGAACACCAAACAACACAGTCAAGTTGAGGAA
AGGGAGTAAGTTTTAATGGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MDTIKAEEISQIISKQIRDYEKKLDVSETGTVLSVGDGIARIYGVENAMAMELLEFPGGIMGMVLNLEADNVGVAVLGDV
THIKEGDIVKRTGKIAQIPVGEALLGRVIDATGEPIDGKGPLGATEFSRIEMIAPGVIKRQPVNEPMYTGLKAIDAMTPI
GRGQRELIIGDRQIGKTAIGIDAIIRQKDTGVKCIYVAIGQKKSTVSQIVENLRKHDAMSYTCVVAGCASDPATLQYIAA
YAGCSIGEYFRDRGQDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDIFYNHSRLLERSARVSADLGGGSLTALPII
ETQAGDVSAYIPTNVISITDGQVYLEPSLFFSGIRPAINVGLSVSRVGGAAQVKAMKQVAGTLKLDLAQYRELASFAQFG
SDLDKATQAQLDRGVRLVEILKQPQFQPMSLAEEVIVLFAGTRGFLDKYEVEKIKEYEPQVLAYMKSKHQDIMQEIDDKK
VISPELEQKIKEALTAFDSVFVAG

Sequences:

>Translated_504_residues
MDTIKAEEISQIISKQIRDYEKKLDVSETGTVLSVGDGIARIYGVENAMAMELLEFPGGIMGMVLNLEADNVGVAVLGDV
THIKEGDIVKRTGKIAQIPVGEALLGRVIDATGEPIDGKGPLGATEFSRIEMIAPGVIKRQPVNEPMYTGLKAIDAMTPI
GRGQRELIIGDRQIGKTAIGIDAIIRQKDTGVKCIYVAIGQKKSTVSQIVENLRKHDAMSYTCVVAGCASDPATLQYIAA
YAGCSIGEYFRDRGQDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDIFYNHSRLLERSARVSADLGGGSLTALPII
ETQAGDVSAYIPTNVISITDGQVYLEPSLFFSGIRPAINVGLSVSRVGGAAQVKAMKQVAGTLKLDLAQYRELASFAQFG
SDLDKATQAQLDRGVRLVEILKQPQFQPMSLAEEVIVLFAGTRGFLDKYEVEKIKEYEPQVLAYMKSKHQDIMQEIDDKK
VISPELEQKIKEALTAFDSVFVAG
>Mature_504_residues
MDTIKAEEISQIISKQIRDYEKKLDVSETGTVLSVGDGIARIYGVENAMAMELLEFPGGIMGMVLNLEADNVGVAVLGDV
THIKEGDIVKRTGKIAQIPVGEALLGRVIDATGEPIDGKGPLGATEFSRIEMIAPGVIKRQPVNEPMYTGLKAIDAMTPI
GRGQRELIIGDRQIGKTAIGIDAIIRQKDTGVKCIYVAIGQKKSTVSQIVENLRKHDAMSYTCVVAGCASDPATLQYIAA
YAGCSIGEYFRDRGQDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDIFYNHSRLLERSARVSADLGGGSLTALPII
ETQAGDVSAYIPTNVISITDGQVYLEPSLFFSGIRPAINVGLSVSRVGGAAQVKAMKQVAGTLKLDLAQYRELASFAQFG
SDLDKATQAQLDRGVRLVEILKQPQFQPMSLAEEVIVLFAGTRGFLDKYEVEKIKEYEPQVLAYMKSKHQDIMQEIDDKK
VISPELEQKIKEALTAFDSVFVAG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=62.8968253968254, Blast_Score=640, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=62.8968253968254, Blast_Score=640, Evalue=0.0,
Organism=Homo sapiens, GI19913426, Length=453, Percent_Identity=26.7108167770419, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=28.476821192053, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI32189394, Length=389, Percent_Identity=27.5064267352185, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI19913424, Length=243, Percent_Identity=26.3374485596708, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1790172, Length=508, Percent_Identity=57.4803149606299, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1788251, Length=322, Percent_Identity=31.6770186335404, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790170, Length=404, Percent_Identity=25.7425742574257, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=61.3545816733068, Blast_Score=636, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=61.3545816733068, Blast_Score=634, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=57.1713147410359, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17570191, Length=323, Percent_Identity=28.1733746130031, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=379, Percent_Identity=26.6490765171504, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=431, Percent_Identity=25.0580046403712, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988068, Length=79, Percent_Identity=48.1012658227848, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565854, Length=242, Percent_Identity=25.6198347107438, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=58.5657370517928, Blast_Score=614, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319603, Length=335, Percent_Identity=28.6567164179104, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=350, Percent_Identity=27.1428571428571, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24658560, Length=507, Percent_Identity=60.9467455621302, Blast_Score=625, Evalue=1e-179,
Organism=Drosophila melanogaster, GI281361666, Length=325, Percent_Identity=27.3846153846154, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24646341, Length=325, Percent_Identity=27.3846153846154, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136796, Length=325, Percent_Identity=27.3846153846154, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24638766, Length=413, Percent_Identity=26.1501210653753, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28574560, Length=431, Percent_Identity=26.6821345707657, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583992, Length=243, Percent_Identity=26.7489711934156, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583988, Length=243, Percent_Identity=26.7489711934156, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24583986, Length=243, Percent_Identity=26.7489711934156, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24583984, Length=243, Percent_Identity=26.7489711934156, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI20129479, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA1_SYNAS (Q2LQZ7)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_460677.1
- ProteinModelPortal:   Q2LQZ7
- SMR:   Q2LQZ7
- STRING:   Q2LQZ7
- GeneID:   3884822
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00546
- NMPDR:   fig|56780.10.peg.624
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q2LQZ7
- ProtClustDB:   PRK09281
- BioCyc:   SACI56780:SYN_00546-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54763; Mature: 54763

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIKAEEISQIISKQIRDYEKKLDVSETGTVLSVGDGIARIYGVENAMAMELLEFPGGI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCE
MGMVLNLEADNVGVAVLGDVTHIKEGDIVKRTGKIAQIPVGEALLGRVIDATGEPIDGKG
EEEEEEEECCCCCEEEECCCCCCCCCCCHHHCCCEEECCCCHHHHHHHHHCCCCCCCCCC
PLGATEFSRIEMIAPGVIKRQPVNEPMYTGLKAIDAMTPIGRGQRELIIGDRQIGKTAIG
CCCCCHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCCHHHH
IDAIIRQKDTGVKCIYVAIGQKKSTVSQIVENLRKHDAMSYTCVVAGCASDPATLQYIAA
HHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHH
YAGCSIGEYFRDRGQDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDIFYNHSRLLE
HHCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHH
RSARVSADLGGGSLTALPIIETQAGDVSAYIPTNVISITDGQVYLEPSLFFSGIRPAINV
HHHHCEEECCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEECHHHHHHCCCHHHHC
GLSVSRVGGAAQVKAMKQVAGTLKLDLAQYRELASFAQFGSDLDKATQAQLDRGVRLVEI
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
LKQPQFQPMSLAEEVIVLFAGTRGFLDKYEVEKIKEYEPQVLAYMKSKHQDIMQEIDDKK
HCCCCCCCHHHHHHHHEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
VISPELEQKIKEALTAFDSVFVAG
CCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTIKAEEISQIISKQIRDYEKKLDVSETGTVLSVGDGIARIYGVENAMAMELLEFPGGI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCE
MGMVLNLEADNVGVAVLGDVTHIKEGDIVKRTGKIAQIPVGEALLGRVIDATGEPIDGKG
EEEEEEEECCCCCEEEECCCCCCCCCCCHHHCCCEEECCCCHHHHHHHHHCCCCCCCCCC
PLGATEFSRIEMIAPGVIKRQPVNEPMYTGLKAIDAMTPIGRGQRELIIGDRQIGKTAIG
CCCCCHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCCHHHH
IDAIIRQKDTGVKCIYVAIGQKKSTVSQIVENLRKHDAMSYTCVVAGCASDPATLQYIAA
HHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHH
YAGCSIGEYFRDRGQDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDIFYNHSRLLE
HHCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHH
RSARVSADLGGGSLTALPIIETQAGDVSAYIPTNVISITDGQVYLEPSLFFSGIRPAINV
HHHHCEEECCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEECHHHHHHCCCHHHHC
GLSVSRVGGAAQVKAMKQVAGTLKLDLAQYRELASFAQFGSDLDKATQAQLDRGVRLVEI
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
LKQPQFQPMSLAEEVIVLFAGTRGFLDKYEVEKIKEYEPQVLAYMKSKHQDIMQEIDDKK
HCCCCCCCHHHHHHHHEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
VISPELEQKIKEALTAFDSVFVAG
CCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA