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The map label for this gene is yacO [H]

Identifier: 85858124

GI number: 85858124

Start: 291368

End: 292117

Strand: Direct

Name: yacO [H]

Synonym: SYN_01282

Alternate gene names: 85858124

Gene position: 291368-292117 (Clockwise)

Preceding gene: 85858123

Following gene: 85858125

Centisome position: 9.16

GC content: 56.53

Gene sequence:

>750_bases
ATGGAGGTGATTTACGGCGTCAATCCTTTAAGAGAAGCGCTGATCAGCGGTGGAGAAGGAGTGACGAGAATTGTAGTCGC
CCGGGGCCGGAGTGAGTCGTCGATCAGCGAGATTCGGACCCTGGCGAAGCAGCGGGGGATTCCTGTGGAGATCCGGGAGC
GGTCGTTTCTGGACGACCTGGCCGGTCATGCCTCTCACCAGGGTGTCCTTGGTGTCTGCACGGCTTATCGCTACCAGGAT
CTGGATGCCGTGATTGCCAACCGTCATCCCTCCTGTCCTTACGATCTGGTGCTTATTCTGGATGGAATTCTGGATCCTCA
TAACCTGGGGGCGCTCATCCGGAGCGCTCACTGCTTCGGAGCCAACGGCATTATTCTGCCCGAGCGCCGTGCGGCTTCCG
TGACAGGAACCGTCATCAAAACATCCGCCGGCGCCGCCCGTCATATTCCCATAGCCCGGGTTGCCAATCTTGCCCGTGCC
CTTGACGAACTGAAAACAAAAGGGTTCTGGATTTTCGGCGCTGATGCGCGTGCAGATCAGTCTGTATCCGACCCTGATTA
CCAAGGCGCCGTGGGTCTGGTCATGGGGGGGGAAAGCAAAGGCCTGAGGCCGCTGATCCGGAAGAAATGCGACGATTTGA
TCTCCATTCCCATGCTGGGTAAAATCGATTCGCTGAACGTCTCTGTATCTGGAGGGATCATTCTCCATGAGATCCGGAGA
AAAAACTGTCCGTTATCATTCACGACCTGA

Upstream 100 bases:

>100_bases
AGCGGAAGACCCTGTGGCTGCGGCGGATGACTTCTGCCGGGAAATCGCACGGGGGCTGAGTGCAAGATAACCCCATGATA
CCTGAGCGACAGAGACGGCC

Downstream 100 bases:

>100_bases
TTTCAAGTACGGATCAGAGATGAAACCAGGGTGGCAAGAGGGGTAAACACAGGCGTATTGAAGCGTGCGTAGAGGAGCTT
CCGGCGAAGCCGTCTCAGAA

Product: 23S rRNA Gm2251 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MEVIYGVNPLREALISGGEGVTRIVVARGRSESSISEIRTLAKQRGIPVEIRERSFLDDLAGHASHQGVLGVCTAYRYQD
LDAVIANRHPSCPYDLVLILDGILDPHNLGALIRSAHCFGANGIILPERRAASVTGTVIKTSAGAARHIPIARVANLARA
LDELKTKGFWIFGADARADQSVSDPDYQGAVGLVMGGESKGLRPLIRKKCDDLISIPMLGKIDSLNVSVSGGIILHEIRR
KNCPLSFTT

Sequences:

>Translated_249_residues
MEVIYGVNPLREALISGGEGVTRIVVARGRSESSISEIRTLAKQRGIPVEIRERSFLDDLAGHASHQGVLGVCTAYRYQD
LDAVIANRHPSCPYDLVLILDGILDPHNLGALIRSAHCFGANGIILPERRAASVTGTVIKTSAGAARHIPIARVANLARA
LDELKTKGFWIFGADARADQSVSDPDYQGAVGLVMGGESKGLRPLIRKKCDDLISIPMLGKIDSLNVSVSGGIILHEIRR
KNCPLSFTT
>Mature_249_residues
MEVIYGVNPLREALISGGEGVTRIVVARGRSESSISEIRTLAKQRGIPVEIRERSFLDDLAGHASHQGVLGVCTAYRYQD
LDAVIANRHPSCPYDLVLILDGILDPHNLGALIRSAHCFGANGIILPERRAASVTGTVIKTSAGAARHIPIARVANLARA
LDELKTKGFWIFGADARADQSVSDPDYQGAVGLVMGGESKGLRPLIRKKCDDLISIPMLGKIDSLNVSVSGGIILHEIRR
KNCPLSFTT

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=265, Percent_Identity=29.4339622641509, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1790623, Length=243, Percent_Identity=37.037037037037, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1788935, Length=239, Percent_Identity=25.5230125523013, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790083, Length=169, Percent_Identity=29.585798816568, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555908, Length=259, Percent_Identity=31.2741312741313, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324775, Length=169, Percent_Identity=32.5443786982249, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26739; Mature: 26739

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVIYGVNPLREALISGGEGVTRIVVARGRSESSISEIRTLAKQRGIPVEIRERSFLDDL
CCEEECCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHH
AGHASHQGVLGVCTAYRYQDLDAVIANRHPSCPYDLVLILDGILDPHNLGALIRSAHCFG
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
ANGIILPERRAASVTGTVIKTSAGAARHIPIARVANLARALDELKTKGFWIFGADARADQ
CCCEEECCCCCCCEECEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
SVSDPDYQGAVGLVMGGESKGLRPLIRKKCDDLISIPMLGKIDSLNVSVSGGIILHEIRR
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEHHH
KNCPLSFTT
CCCCCCCCC
>Mature Secondary Structure
MEVIYGVNPLREALISGGEGVTRIVVARGRSESSISEIRTLAKQRGIPVEIRERSFLDDL
CCEEECCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHH
AGHASHQGVLGVCTAYRYQDLDAVIANRHPSCPYDLVLILDGILDPHNLGALIRSAHCFG
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
ANGIILPERRAASVTGTVIKTSAGAARHIPIARVANLARALDELKTKGFWIFGADARADQ
CCCEEECCCCCCCEECEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
SVSDPDYQGAVGLVMGGESKGLRPLIRKKCDDLISIPMLGKIDSLNVSVSGGIILHEIRR
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEHHH
KNCPLSFTT
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]