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The map label for this gene is ygbD [C]

Identifier: 85858090

GI number: 85858090

Start: 260485

End: 261924

Strand: Direct

Name: ygbD [C]

Synonym: SYN_01441

Alternate gene names: 85858090

Gene position: 260485-261924 (Clockwise)

Preceding gene: 85858089

Following gene: 85858091

Centisome position: 8.19

GC content: 58.82

Gene sequence:

>1440_bases
ATGGACATTGCCCGGTGGAAATCGGGCGATGAACAGGCCTTTGTTTTCCCCCAGTCGTGCGGAAGACGGAAAGGATGGGT
GAAGTACATGAAAAGACGAGTCGTGATTATCGGCGGCGGTGCGGGCGGTCCATCAACGGCCGCGGAGGCCGGGCGACGGG
ATCCTTCGCTGGCCATCACCATGATCGAAAAGGGAGAATATATCTCCTACGCGGCCTGTCCGATGCCCTATTACATCGGC
GATGTGATTAAAGACGAAAAGAAATTGATCGCCCGGACGCCGGAGAAATTCCGGGAAGGAGGCGTAGACGTCCGGACCGG
CGTGGAGGCGGAGAATGTTGACCTTGCGGCACAGGTGGTTACTCTCGTCGGGGGGGAAGCACTCCCCTTTGACGTTCTTG
TGCTGGCAACGGGAACCCGTCCGATTCTTCCGGGAATCCCCGGTGAAGATCGAGAGGGAGTTTTTACCCTGAAACAGCTG
CCCGACGCCGTGGGGATCAAGCAGTTTATCCGGGAGAGCCGCTGCCGGACGGCCATCATCGTCGGGGCCGGGTTTATCGG
CATGGAAATGTGTGAAGCTTTTCGGGAAGCCGGTGTGGAGACCACGGTGGTCAATCGGGGAAGCATGCCTGTGCCCCGGT
GGGACCCCGAACTGGGGCAACTGGTTGTCAAATCTCTTCTGGACCATCAAATCAGGATGATGGCCGACACGACCATCCAG
GCCATTGAAAAGGGGGAGACATGCCGGCTCCGGTTGATTACCGATCAGGGCAAGATTGAAGCCGATGTGATCCTGCTGGC
TATTGGTGTGCGCCCCAGTGTCGGGTTGGCCGGCGAAATGGGCCTCGCCCTGGGGAAAACGGGTGCGGTTGCCGTGGATT
TTTCTCAGAAAACATCCCATCCGGCGGTTTATGCCGTGGGGGACTGCTGCGAAGCGTATCACCGGGTCAGCAGAAGGTGG
GTCCATATCCCGTTGGGAGACATCGCCAACAAGCAGGGCCGGGTGGCGGGGTGCAACATCGGAGGCTTTCCCACGATTTT
TCCGGGGATCGTCGGCGCACAGGCCTTCAAACTTTTCGATCTGGAGATCGCCGCGACAGGGCTGGATGAAAGGGAAGCTC
TCGCAGCGGGTTTTCATCCCGTCAGCAACCTTGTATGGGGCGATGTGGTGCCACTTTCCGTGCCGGGAACGACCCGGCTC
GGTCTGAAACTCATTGCTGATGAAGCAACGGGGCTTTTTCTCGGCGCGCAGGCTATTGGTCCTCATGGAGCGGTCAGCCG
GATCAATACCCTTTCCGCGGCCCTCTGGTCGGGGCTTTCTATTGATGAAGTCGCTTATCTTGATCTCGCCTATTCACCCC
CTTTCAGCCGCGCCTGGGATCTGATCCACATTGCCGCCCAGGATCTCATGAAGAAAATGGTTCGGAGGCCCCCGCGCTGA

Upstream 100 bases:

>100_bases
GCAGGCTCTCTGCCTTCTCATGATGGCAGCCGGCGTTCTGGTGTATATTCTTCGCAGGCCGCAGAAGAGCGGATCGCAGG
TTGATCCTGTTTAGAAGTAC

Downstream 100 bases:

>100_bases
GCGGTCATTTTCTGACGGAAATCAGCCGGTCTGTGCCGTTTTGCGATTGGACAAATATTTCGAGCGCAGCGGGACCGCAA
GAATTCCGCACTTTTTTGCG

Product: pyridine nucleotide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MDIARWKSGDEQAFVFPQSCGRRKGWVKYMKRRVVIIGGGAGGPSTAAEAGRRDPSLAITMIEKGEYISYAACPMPYYIG
DVIKDEKKLIARTPEKFREGGVDVRTGVEAENVDLAAQVVTLVGGEALPFDVLVLATGTRPILPGIPGEDREGVFTLKQL
PDAVGIKQFIRESRCRTAIIVGAGFIGMEMCEAFREAGVETTVVNRGSMPVPRWDPELGQLVVKSLLDHQIRMMADTTIQ
AIEKGETCRLRLITDQGKIEADVILLAIGVRPSVGLAGEMGLALGKTGAVAVDFSQKTSHPAVYAVGDCCEAYHRVSRRW
VHIPLGDIANKQGRVAGCNIGGFPTIFPGIVGAQAFKLFDLEIAATGLDEREALAAGFHPVSNLVWGDVVPLSVPGTTRL
GLKLIADEATGLFLGAQAIGPHGAVSRINTLSAALWSGLSIDEVAYLDLAYSPPFSRAWDLIHIAAQDLMKKMVRRPPR

Sequences:

>Translated_479_residues
MDIARWKSGDEQAFVFPQSCGRRKGWVKYMKRRVVIIGGGAGGPSTAAEAGRRDPSLAITMIEKGEYISYAACPMPYYIG
DVIKDEKKLIARTPEKFREGGVDVRTGVEAENVDLAAQVVTLVGGEALPFDVLVLATGTRPILPGIPGEDREGVFTLKQL
PDAVGIKQFIRESRCRTAIIVGAGFIGMEMCEAFREAGVETTVVNRGSMPVPRWDPELGQLVVKSLLDHQIRMMADTTIQ
AIEKGETCRLRLITDQGKIEADVILLAIGVRPSVGLAGEMGLALGKTGAVAVDFSQKTSHPAVYAVGDCCEAYHRVSRRW
VHIPLGDIANKQGRVAGCNIGGFPTIFPGIVGAQAFKLFDLEIAATGLDEREALAAGFHPVSNLVWGDVVPLSVPGTTRL
GLKLIADEATGLFLGAQAIGPHGAVSRINTLSAALWSGLSIDEVAYLDLAYSPPFSRAWDLIHIAAQDLMKKMVRRPPR
>Mature_479_residues
MDIARWKSGDEQAFVFPQSCGRRKGWVKYMKRRVVIIGGGAGGPSTAAEAGRRDPSLAITMIEKGEYISYAACPMPYYIG
DVIKDEKKLIARTPEKFREGGVDVRTGVEAENVDLAAQVVTLVGGEALPFDVLVLATGTRPILPGIPGEDREGVFTLKQL
PDAVGIKQFIRESRCRTAIIVGAGFIGMEMCEAFREAGVETTVVNRGSMPVPRWDPELGQLVVKSLLDHQIRMMADTTIQ
AIEKGETCRLRLITDQGKIEADVILLAIGVRPSVGLAGEMGLALGKTGAVAVDFSQKTSHPAVYAVGDCCEAYHRVSRRW
VHIPLGDIANKQGRVAGCNIGGFPTIFPGIVGAQAFKLFDLEIAATGLDEREALAAGFHPVSNLVWGDVVPLSVPGTTRL
GLKLIADEATGLFLGAQAIGPHGAVSRINTLSAALWSGLSIDEVAYLDLAYSPPFSRAWDLIHIAAQDLMKKMVRRPPR

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=313, Percent_Identity=27.7955271565495, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI226437568, Length=313, Percent_Identity=27.7955271565495, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI65787454, Length=313, Percent_Identity=27.7955271565495, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1789065, Length=284, Percent_Identity=27.112676056338, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789765, Length=345, Percent_Identity=25.7971014492754, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788892, Length=286, Percent_Identity=24.1258741258741, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789915, Length=194, Percent_Identity=28.8659793814433, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786307, Length=316, Percent_Identity=25.3164556962025, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559934, Length=289, Percent_Identity=24.2214532871972, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6325166, Length=192, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639257, Length=319, Percent_Identity=26.6457680250784, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281359715, Length=319, Percent_Identity=26.6457680250784, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281359713, Length=319, Percent_Identity=26.6457680250784, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639250, Length=319, Percent_Identity=26.6457680250784, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI18543267, Length=319, Percent_Identity=26.6457680250784, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639252, Length=319, Percent_Identity=26.6457680250784, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24585130, Length=377, Percent_Identity=22.0159151193634, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 51496; Mature: 51496

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIARWKSGDEQAFVFPQSCGRRKGWVKYMKRRVVIIGGGAGGPSTAAEAGRRDPSLAIT
CCCCCCCCCCCCEEEECHHCCCCHHHHHHHHCEEEEEECCCCCCCHHHHCCCCCCCEEEE
MIEKGEYISYAACPMPYYIGDVIKDEKKLIARTPEKFREGGVDVRTGVEAENVDLAAQVV
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCCCHHHHHHH
TLVGGEALPFDVLVLATGTRPILPGIPGEDREGVFTLKQLPDAVGIKQFIRESRCRTAII
HHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEHHHCCCCCCHHHHHHHCCCCEEEE
VGAGFIGMEMCEAFREAGVETTVVNRGSMPVPRWDPELGQLVVKSLLDHQIRMMADTTIQ
EECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIEKGETCRLRLITDQGKIEADVILLAIGVRPSVGLAGEMGLALGKTGAVAVDFSQKTSH
HHHCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCEECCCCCEEEEECCCCCC
PAVYAVGDCCEAYHRVSRRWVHIPLGDIANKQGRVAGCNIGGFPTIFPGIVGAQAFKLFD
CEEEEHHHHHHHHHHHHHCEEEEEHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHEEEEE
LEIAATGLDEREALAAGFHPVSNLVWGDVVPLSVPGTTRLGLKLIADEATGLFLGAQAIG
EEEEECCCCHHHHHHHCCCHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCEEEECHHCC
PHGAVSRINTLSAALWSGLSIDEVAYLDLAYSPPFSRAWDLIHIAAQDLMKKMVRRPPR
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIARWKSGDEQAFVFPQSCGRRKGWVKYMKRRVVIIGGGAGGPSTAAEAGRRDPSLAIT
CCCCCCCCCCCCEEEECHHCCCCHHHHHHHHCEEEEEECCCCCCCHHHHCCCCCCCEEEE
MIEKGEYISYAACPMPYYIGDVIKDEKKLIARTPEKFREGGVDVRTGVEAENVDLAAQVV
EEECCCEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHCCCEEECCCCCCCCHHHHHHH
TLVGGEALPFDVLVLATGTRPILPGIPGEDREGVFTLKQLPDAVGIKQFIRESRCRTAII
HHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEHHHCCCCCCHHHHHHHCCCCEEEE
VGAGFIGMEMCEAFREAGVETTVVNRGSMPVPRWDPELGQLVVKSLLDHQIRMMADTTIQ
EECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIEKGETCRLRLITDQGKIEADVILLAIGVRPSVGLAGEMGLALGKTGAVAVDFSQKTSH
HHHCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCEECCCCCEEEEECCCCCC
PAVYAVGDCCEAYHRVSRRWVHIPLGDIANKQGRVAGCNIGGFPTIFPGIVGAQAFKLFD
CEEEEHHHHHHHHHHHHHCEEEEEHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHEEEEE
LEIAATGLDEREALAAGFHPVSNLVWGDVVPLSVPGTTRLGLKLIADEATGLFLGAQAIG
EEEEECCCCHHHHHHHCCCHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCEEEECHHCC
PHGAVSRINTLSAALWSGLSIDEVAYLDLAYSPPFSRAWDLIHIAAQDLMKKMVRRPPR
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA