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The map label for this gene is rbr [H]

Identifier: 85858039

GI number: 85858039

Start: 202441

End: 203316

Strand: Direct

Name: rbr [H]

Synonym: SYN_02559

Alternate gene names: 85858039

Gene position: 202441-203316 (Clockwise)

Preceding gene: 85858038

Following gene: 85858042

Centisome position: 6.37

GC content: 54.57

Gene sequence:

>876_bases
ATGGAGTTGAAGGGAAGCAGGACCGAAGACGTTTTACGGAAAGCATTGAATGCGGAATTGCGTCAGAGTTTCGAATATCG
CTACTTTGCCGGAATGGCGCGGCAGGCGGGTCTTCAGCAGGTTGCGGAGATTTTTGAGGCTACCGCAGCCAATGAACTGG
AGCATGCCCGCCATGAATATGAATTTCTCGGAGGTGCAGGGAATTCGCTGGAAAATGTCCGGCAGGCCGTCAGCAATGAA
CACGATCAGGTTCTTAAATTCTACCCGCAGGCTGCGGAAACGGCCGAGCAGGAGGGGTTTACAGAGATTGCTGAATTCTT
CCGACGGATTGTCGATGTCGAGGAAAAGCACGAGAAGAATTTTCAGGAACTGCTGCATGGGATAGAAAAGGAGACTGAAT
TCGAAGGCCGAACCGTGGGACATTCCTCTGTGGAGATGGCGCAGTTGATGCTGCCGGAGCAGGCTAACCCGGCTGGATTC
GTGCATGGCGGGGAATTGATGAAGATGATGGATAATGCGGCCGGGGTGGTGGCCGCCCGGCATGCGCATTCCAATGTCGT
TACCGCCCGGGTGGAGGACATTGTCTTTCAGAGTCCGGTTCGCGTCGGCAGCGTGGTTTTCGTGAAAGCCAGACTCGTGT
TTGCCAGCCGCTCCTCCATGGTCATCCGGGTCGACCTGGAGATGGAACATATCAGCCTGGAAAAGGGCCATGACGGCCAG
GAACATAGAGTCCCCGCGATGACGGCAAATTTCGTGATGGTGGCCGTGGATGAACAGGGAAAGGCCAGTGCCGTTCCAAA
ACTGATCCTGCTTACGGAAGAAGAGGAAAGGCTCTTCGCCGCCGCAGAGGAGGGCTATAAAGCAAGAAAGAAATAG

Upstream 100 bases:

>100_bases
GCCCATACGGGGAGGAGAATGACAGACACCGTAACATCGCTGTTTCCATGCCGTCGAGGTTAACCGGGTCATATCTTAAA
TCTTCTCACAGGAGGTAAAA

Downstream 100 bases:

>100_bases
GCTATGCCGAAAAAAAGCAGGCGAATCCCGCATCTGTCAGTCTGTCAAGGGCCAGGGCCGAAGTCCCACGACAGGAATCC
GGCTTTCCTCTGAAATAGAG

Product: rubrerythrin and thioesterase superfamily protein

Products: NA

Alternate protein names: RR [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MELKGSRTEDVLRKALNAELRQSFEYRYFAGMARQAGLQQVAEIFEATAANELEHARHEYEFLGGAGNSLENVRQAVSNE
HDQVLKFYPQAAETAEQEGFTEIAEFFRRIVDVEEKHEKNFQELLHGIEKETEFEGRTVGHSSVEMAQLMLPEQANPAGF
VHGGELMKMMDNAAGVVAARHAHSNVVTARVEDIVFQSPVRVGSVVFVKARLVFASRSSMVIRVDLEMEHISLEKGHDGQ
EHRVPAMTANFVMVAVDEQGKASAVPKLILLTEEEERLFAAAEEGYKARKK

Sequences:

>Translated_291_residues
MELKGSRTEDVLRKALNAELRQSFEYRYFAGMARQAGLQQVAEIFEATAANELEHARHEYEFLGGAGNSLENVRQAVSNE
HDQVLKFYPQAAETAEQEGFTEIAEFFRRIVDVEEKHEKNFQELLHGIEKETEFEGRTVGHSSVEMAQLMLPEQANPAGF
VHGGELMKMMDNAAGVVAARHAHSNVVTARVEDIVFQSPVRVGSVVFVKARLVFASRSSMVIRVDLEMEHISLEKGHDGQ
EHRVPAMTANFVMVAVDEQGKASAVPKLILLTEEEERLFAAAEEGYKARKK
>Mature_291_residues
MELKGSRTEDVLRKALNAELRQSFEYRYFAGMARQAGLQQVAEIFEATAANELEHARHEYEFLGGAGNSLENVRQAVSNE
HDQVLKFYPQAAETAEQEGFTEIAEFFRRIVDVEEKHEKNFQELLHGIEKETEFEGRTVGHSSVEMAQLMLPEQANPAGF
VHGGELMKMMDNAAGVVAARHAHSNVVTARVEDIVFQSPVRVGSVVFVKARLVFASRSSMVIRVDLEMEHISLEKGHDGQ
EHRVPAMTANFVMVAVDEQGKASAVPKLILLTEEEERLFAAAEEGYKARKK

Specific function: May provide oxidative stress protection via catalytic reduction of intracellular hydrogen peroxide [H]

COG id: COG1592

COG function: function code C; Rubrerythrin

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rubredoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI32528284, Length=151, Percent_Identity=37.7483443708609, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI32528286, Length=151, Percent_Identity=37.7483443708609, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI75709208, Length=151, Percent_Identity=37.7483443708609, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32528282, Length=151, Percent_Identity=37.7483443708609, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI22165355, Length=94, Percent_Identity=38.2978723404255, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22165400, Length=94, Percent_Identity=38.2978723404255, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787506, Length=118, Percent_Identity=38.135593220339, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009040
- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR004039
- InterPro:   IPR003251 [H]

Pfam domain/function: PF02915 Rubrerythrin [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 32571; Mature: 32571

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50905 FERRITIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKGSRTEDVLRKALNAELRQSFEYRYFAGMARQAGLQQVAEIFEATAANELEHARHEY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFLGGAGNSLENVRQAVSNEHDQVLKFYPQAAETAEQEGFTEIAEFFRRIVDVEEKHEKN
HHHCCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
FQELLHGIEKETEFEGRTVGHSSVEMAQLMLPEQANPAGFVHGGELMKMMDNAAGVVAAR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
HAHSNVVTARVEDIVFQSPVRVGSVVFVKARLVFASRSSMVIRVDLEMEHISLEKGHDGQ
HCCCCHHHHHHHHHHHHCCCHHHHEEEHHHHHHEECCCCEEEEEEEEEEEEECCCCCCCC
EHRVPAMTANFVMVAVDEQGKASAVPKLILLTEEEERLFAAAEEGYKARKK
CCCCCEEEECEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELKGSRTEDVLRKALNAELRQSFEYRYFAGMARQAGLQQVAEIFEATAANELEHARHEY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFLGGAGNSLENVRQAVSNEHDQVLKFYPQAAETAEQEGFTEIAEFFRRIVDVEEKHEKN
HHHCCCCCHHHHHHHHHCCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
FQELLHGIEKETEFEGRTVGHSSVEMAQLMLPEQANPAGFVHGGELMKMMDNAAGVVAAR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
HAHSNVVTARVEDIVFQSPVRVGSVVFVKARLVFASRSSMVIRVDLEMEHISLEKGHDGQ
HCCCCHHHHHHHHHHHHCCCHHHHEEEHHHHHHEECCCCEEEEEEEEEEEEECCCCCCCC
EHRVPAMTANFVMVAVDEQGKASAVPKLILLTEEEERLFAAAEEGYKARKK
CCCCCEEEECEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11972784; 12949112 [H]