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The map label for this gene is yfgC [H]

Identifier: 85857949

GI number: 85857949

Start: 105592

End: 106455

Strand: Direct

Name: yfgC [H]

Synonym: SYN_02199

Alternate gene names: 85857949

Gene position: 105592-106455 (Clockwise)

Preceding gene: 85857948

Following gene: 85857954

Centisome position: 3.32

GC content: 56.13

Gene sequence:

>864_bases
GTGCATATGATGGGCAATATTTCTTCGAAAAACGGCAAACGCTTCTTTTCCCCGCGAAAAGCCTTTCTGTTGGGAATGGC
CGGTCTGGCTCTGATTTTTTTCCTGCTGTCCTGCACGACTGTTCCCCTTACCGGAAGAAGCAGTCTGAGCCTGGTTCCCG
ATTCAGAACTGGTGACAATGAGTTATCAGCAATATAACGATGTCCTGAAGAAGGCGACGCTTTCCCGGGATGCGGAAAAG
GTGCAGATGGTCAAGCGGGTCGGCGGAAGAATTGCCGCTGCCGCGGAATCCTTTTTGAGAGAATCAGGCGCGGGGGCGGA
AGTCGCGCAGTACAAATGGGAGTTCAACCTGATTGAAGACGACAAGACGGTTAATGCCTGGTGCATGCCCGGCGGCAAAG
TGGCTGTGTATACGGGGATTCTTCCCATTACCCGGGATGAAACGGGGTTGGCCGTCGTGGTGGGGCATGAGGTGGCCCAT
GCCATAGCACGACACGGGAACGAAAGGATGAGCCAGGCCCTTCTCGTTCAGTTCGGGGGGATCGGTTTGTCCGCGGCCCT
GGCCAGTCAGGCTGCGGCCACTCAGGAGCTTTTTCTCCAACTTTACGGCGTCGGCGCGAACATCGGTTACATGCTTCCTT
ACAGCCGTCTCCACGAAAACGAAGCGGATCGGATCGGTCTGGTTCTCATGGCCAAGGCCGGTTATGACCCGAGAGCCGCA
GTGGGGCTCTGGCAGAGGATGAATGCCCAGGGCGGTGGGCGCACTCTGGAATTTTTATCCACCCACCCGGCGCCAACAAC
CCGGATTGCGAATATTGAATCTCTCATTCCCGAAGCGATGCGCTATTATCAGAAACCCCGGTAG

Upstream 100 bases:

>100_bases
TTCGCCTTTCTCTTCGCCTTTGCCGGCCTGCAGAAAATTCTGTCCTGAAGGCTGACCGCAGGCGGAAATCCTTACGTGAC
GTCTCATTAATAGAGGAGGT

Downstream 100 bases:

>100_bases
CCATGGTAACCAGGATAACTTCTGCCGCCGGCTGTTCATCCTGGTGGGCGAGTCGCAGGGTCTTGAGGATCTGCGGAACT
CCAATGGCCGGTGTCACGAA

Product: Zn-dependent protease with chaperone function

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MHMMGNISSKNGKRFFSPRKAFLLGMAGLALIFFLLSCTTVPLTGRSSLSLVPDSELVTMSYQQYNDVLKKATLSRDAEK
VQMVKRVGGRIAAAAESFLRESGAGAEVAQYKWEFNLIEDDKTVNAWCMPGGKVAVYTGILPITRDETGLAVVVGHEVAH
AIARHGNERMSQALLVQFGGIGLSAALASQAAATQELFLQLYGVGANIGYMLPYSRLHENEADRIGLVLMAKAGYDPRAA
VGLWQRMNAQGGGRTLEFLSTHPAPTTRIANIESLIPEAMRYYQKPR

Sequences:

>Translated_287_residues
MHMMGNISSKNGKRFFSPRKAFLLGMAGLALIFFLLSCTTVPLTGRSSLSLVPDSELVTMSYQQYNDVLKKATLSRDAEK
VQMVKRVGGRIAAAAESFLRESGAGAEVAQYKWEFNLIEDDKTVNAWCMPGGKVAVYTGILPITRDETGLAVVVGHEVAH
AIARHGNERMSQALLVQFGGIGLSAALASQAAATQELFLQLYGVGANIGYMLPYSRLHENEADRIGLVLMAKAGYDPRAA
VGLWQRMNAQGGGRTLEFLSTHPAPTTRIANIESLIPEAMRYYQKPR
>Mature_287_residues
MHMMGNISSKNGKRFFSPRKAFLLGMAGLALIFFLLSCTTVPLTGRSSLSLVPDSELVTMSYQQYNDVLKKATLSRDAEK
VQMVKRVGGRIAAAAESFLRESGAGAEVAQYKWEFNLIEDDKTVNAWCMPGGKVAVYTGILPITRDETGLAVVVGHEVAH
AIARHGNERMSQALLVQFGGIGLSAALASQAAATQELFLQLYGVGANIGYMLPYSRLHENEADRIGLVLMAKAGYDPRAA
VGLWQRMNAQGGGRTLEFLSTHPAPTTRIANIESLIPEAMRYYQKPR

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=273, Percent_Identity=30.4029304029304, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1788840, Length=245, Percent_Identity=27.3469387755102, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081800, Length=155, Percent_Identity=30.9677419354839, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322940, Length=278, Percent_Identity=29.136690647482, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 31241; Mature: 31241

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMMGNISSKNGKRFFSPRKAFLLGMAGLALIFFLLSCTTVPLTGRSSLSLVPDSELVTM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEE
SYQQYNDVLKKATLSRDAEKVQMVKRVGGRIAAAAESFLRESGAGAEVAQYKWEFNLIED
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEECC
DKTVNAWCMPGGKVAVYTGILPITRDETGLAVVVGHEVAHAIARHGNERMSQALLVQFGG
CCCEEEEECCCCCEEEEEEEEEEEECCCCEEEEECHHHHHHHHHCCHHHHHHHHHHHHCC
IGLSAALASQAAATQELFLQLYGVGANIGYMLPYSRLHENEADRIGLVLMAKAGYDPRAA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCCEEEEEEEECCCCCHHH
VGLWQRMNAQGGGRTLEFLSTHPAPTTRIANIESLIPEAMRYYQKPR
HHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHMMGNISSKNGKRFFSPRKAFLLGMAGLALIFFLLSCTTVPLTGRSSLSLVPDSELVTM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEE
SYQQYNDVLKKATLSRDAEKVQMVKRVGGRIAAAAESFLRESGAGAEVAQYKWEFNLIED
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEECC
DKTVNAWCMPGGKVAVYTGILPITRDETGLAVVVGHEVAHAIARHGNERMSQALLVQFGG
CCCEEEEECCCCCEEEEEEEEEEEECCCCEEEEECHHHHHHHHHCCHHHHHHHHHHHHCC
IGLSAALASQAAATQELFLQLYGVGANIGYMLPYSRLHENEADRIGLVLMAKAGYDPRAA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCCEEEEEEEECCCCCHHH
VGLWQRMNAQGGGRTLEFLSTHPAPTTRIANIESLIPEAMRYYQKPR
HHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]