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The map label for this gene is nuoG2 [H]

Identifier: 85857934

GI number: 85857934

Start: 89997

End: 90719

Strand: Direct

Name: nuoG2 [H]

Synonym: SYN_00151

Alternate gene names: 85857934

Gene position: 89997-90719 (Clockwise)

Preceding gene: 85857933

Following gene: 85857937

Centisome position: 2.83

GC content: 56.29

Gene sequence:

>723_bases
ATGGTGAATTTAGTCATAGATGGGAAGAAGATCGAGGCAGAGACCGGCACAACAATCCTTTCCGCTGCCCGGGACAACGG
GATCGTCATTCCGACCTTGTGTCATCACGAGTCGATTGAGGCGTCAGGCGCTTGCCGGCTGTGCGTCGTGGAGATCGCAA
AGGGCGGGAGAAAGCGTATCGTTACCTCCTGCATTTATCTTGTCGAAGACGGCATCGTTGTTGATACAAAAAGCGAACGC
GTTCTTGGGGTCCGACGCCTCGTCCTGGAGCTGCTTATGGCCCGGTGTCCGGAATCCGAGGTGGTGCGGAACCTGGCTGA
AGAGCTTGGCGTCAAAACTCAGAAACGCTTCAAGCCTGATAAGGACAAGGGCAAGTGCATCCTGTGCCGGTTGTGTGTAA
AGACCTGTGAAGATATCGTGGGCGTGTCCGCCATCGGATTGTCCTTCCGCGGGAAGGATAAGGTGGTTGGTCCCCCTTTC
ACGGAGGATTCGAAGGCCTGCATCGGCTGTGGCGCCTGTGCTTATGTATGCCCGACGGGGCACATCGAGATGACCACCGG
CAACGGCGGCGCCGAGCGCACAATCTGGGGACGAACCTTCAAAATGGCACAATGCAGCGTCTGCGGTCAGTACTTTGCCC
CGGAGGATCAGCTTCAATATATCAGCAACAAGACGGGTGTGCCGATGGAGAACCTCACCGTCTGTATGAACTGCCGGCTG
TAA

Upstream 100 bases:

>100_bases
AAAAGGCCCACGAGATTGACCAGGCGAAATGCATCAAGTGCGGAGTTTGCATGGAAACGTGCAAGTTTGATGCGATAACC
TTATCATAAAGGTAGGCGAG

Downstream 100 bases:

>100_bases
GCCGGGAGACCCTGGCAGCAGAGACACATGAATTAGAGATACATACTCCTCAGTAGCTCAGTCGGTAGAGCAGATGGCTG
TTAACCATCGGGTCCGTGGT

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MVNLVIDGKKIEAETGTTILSAARDNGIVIPTLCHHESIEASGACRLCVVEIAKGGRKRIVTSCIYLVEDGIVVDTKSER
VLGVRRLVLELLMARCPESEVVRNLAEELGVKTQKRFKPDKDKGKCILCRLCVKTCEDIVGVSAIGLSFRGKDKVVGPPF
TEDSKACIGCGACAYVCPTGHIEMTTGNGGAERTIWGRTFKMAQCSVCGQYFAPEDQLQYISNKTGVPMENLTVCMNCRL

Sequences:

>Translated_240_residues
MVNLVIDGKKIEAETGTTILSAARDNGIVIPTLCHHESIEASGACRLCVVEIAKGGRKRIVTSCIYLVEDGIVVDTKSER
VLGVRRLVLELLMARCPESEVVRNLAEELGVKTQKRFKPDKDKGKCILCRLCVKTCEDIVGVSAIGLSFRGKDKVVGPPF
TEDSKACIGCGACAYVCPTGHIEMTTGNGGAERTIWGRTFKMAQCSVCGQYFAPEDQLQYISNKTGVPMENLTVCMNCRL
>Mature_240_residues
MVNLVIDGKKIEAETGTTILSAARDNGIVIPTLCHHESIEASGACRLCVVEIAKGGRKRIVTSCIYLVEDGIVVDTKSER
VLGVRRLVLELLMARCPESEVVRNLAEELGVKTQKRFKPDKDKGKCILCRLCVKTCEDIVGVSAIGLSFRGKDKVVGPPF
TEDSKACIGCGACAYVCPTGHIEMTTGNGGAERTIWGRTFKMAQCSVCGQYFAPEDQLQYISNKTGVPMENLTVCMNCRL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=204, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=9e-17,
Organism=Escherichia coli, GI145693161, Length=265, Percent_Identity=25.6603773584906, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209088, Length=207, Percent_Identity=28.5024154589372, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566231, Length=207, Percent_Identity=28.5024154589372, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565758, Length=207, Percent_Identity=28.5024154589372, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640559, Length=207, Percent_Identity=28.5024154589372, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640557, Length=207, Percent_Identity=28.5024154589372, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 26052; Mature: 26052

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00196 COPPER_BLUE ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
7.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLVIDGKKIEAETGTTILSAARDNGIVIPTLCHHESIEASGACRLCVVEIAKGGRKRI
CEEEEECCCEEECCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEHHCCCHHHH
VTSCIYLVEDGIVVDTKSERVLGVRRLVLELLMARCPESEVVRNLAEELGVKTQKRFKPD
HHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCCC
KDKGKCILCRLCVKTCEDIVGVSAIGLSFRGKDKVVGPPFTEDSKACIGCGACAYVCPTG
CCCCCCHHHHHHHHHHHHHHCHHHCCEEECCCCCCCCCCCCCCCCCEEECCCEEEECCCC
HIEMTTGNGGAERTIWGRTFKMAQCSVCGQYFAPEDQLQYISNKTGVPMENLTVCMNCRL
CEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHEEEEEECCC
>Mature Secondary Structure
MVNLVIDGKKIEAETGTTILSAARDNGIVIPTLCHHESIEASGACRLCVVEIAKGGRKRI
CEEEEECCCEEECCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEHHCCCHHHH
VTSCIYLVEDGIVVDTKSERVLGVRRLVLELLMARCPESEVVRNLAEELGVKTQKRFKPD
HHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCCCC
KDKGKCILCRLCVKTCEDIVGVSAIGLSFRGKDKVVGPPFTEDSKACIGCGACAYVCPTG
CCCCCCHHHHHHHHHHHHHHCHHHCCEEECCCCCCCCCCCCCCCCCEEECCCEEEECCCC
HIEMTTGNGGAERTIWGRTFKMAQCSVCGQYFAPEDQLQYISNKTGVPMENLTVCMNCRL
CEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]