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The map label for this gene is sucD [H]

Identifier: 85857866

GI number: 85857866

Start: 24436

End: 24978

Strand: Direct

Name: sucD [H]

Synonym: SYN_00001

Alternate gene names: 85857866

Gene position: 24436-24978 (Clockwise)

Preceding gene: 85857865

Following gene: 85857868

Centisome position: 0.77

GC content: 59.85

Gene sequence:

>543_bases
ATGCCATGGAAAACGGCGTCTTTGCCCTGGGGCCGACAACACCGGGGCATTCTTGTTCCGGGCAAAGGCAAGATGGGCAT
CATGCCGGCATCCATGTTCGCTCCGGGACGGGTCGGCATCATTTCCCGAAGCGGGACGCTCTCCTATGAATTCGCCGGAA
TTCTTTCGGAGAACAACGTGGGGCAGAGCACCGTTGTCGGCATGGGCGCGGATCCGGTCGTGCTGAGAAACCTTACGGAT
ATTCTGGAACTCTTTGAGGAAGACGAAGGAACGGACGCGGTGATCGTGGTCGGAGAGGTCGGCGGGGAACAGGAAGAGAA
GGCCGCCGGGTTCATCAAAAGGAGGATGACCAAGCCGGTGGCGGCCTACATCGCCGGACGTTATTCGCCGCAGGGAAAAC
GGATGGGCCATGCGGGCGCGATCGTGCGCGGCGCCTCGGGAACGGTTGCAGGCAAGCAGGAGGCGTTGAGAGACGCCGGA
GTAACCATCCTCGACTCCCCCATCCATGTTGCCGATTGGGCCGTTAAACATAAATTGAGTTAG

Upstream 100 bases:

>100_bases
GTCCTTGACGCCTTCATGGAGACCATCGATGCTGGGATCAAACTCATTGTCATCGTGCCGGAGCACATCCCTGTCCGGGA
TGTGATGAAGATGCGCAGCT

Downstream 100 bases:

>100_bases
AGTTTCTCTGAAAAAAAATACGGCGAACATTTTTGCCGGTAGTCCGATAGATTAAAACCATCCTTTCCGTTTTTCGGATC
GATAAGCTGCCTCACCTCCG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MPWKTASLPWGRQHRGILVPGKGKMGIMPASMFAPGRVGIISRSGTLSYEFAGILSENNVGQSTVVGMGADPVVLRNLTD
ILELFEEDEGTDAVIVVGEVGGEQEEKAAGFIKRRMTKPVAAYIAGRYSPQGKRMGHAGAIVRGASGTVAGKQEALRDAG
VTILDSPIHVADWAVKHKLS

Sequences:

>Translated_180_residues
MPWKTASLPWGRQHRGILVPGKGKMGIMPASMFAPGRVGIISRSGTLSYEFAGILSENNVGQSTVVGMGADPVVLRNLTD
ILELFEEDEGTDAVIVVGEVGGEQEEKAAGFIKRRMTKPVAAYIAGRYSPQGKRMGHAGAIVRGASGTVAGKQEALRDAG
VTILDSPIHVADWAVKHKLS
>Mature_179_residues
PWKTASLPWGRQHRGILVPGKGKMGIMPASMFAPGRVGIISRSGTLSYEFAGILSENNVGQSTVVGMGADPVVLRNLTDI
LELFEEDEGTDAVIVVGEVGGEQEEKAAGFIKRRMTKPVAAYIAGRYSPQGKRMGHAGAIVRGASGTVAGKQEALRDAGV
TILDSPIHVADWAVKHKLS

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=165, Percent_Identity=43.6363636363636, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI38569421, Length=156, Percent_Identity=32.0512820512821, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI38569423, Length=156, Percent_Identity=32.0512820512821, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786949, Length=156, Percent_Identity=50.6410256410256, Blast_Score=159, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17553126, Length=156, Percent_Identity=48.0769230769231, Blast_Score=130, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17550194, Length=156, Percent_Identity=46.1538461538462, Blast_Score=122, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17557344, Length=159, Percent_Identity=32.0754716981132, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=159, Percent_Identity=30.8176100628931, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324716, Length=160, Percent_Identity=45.625, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21356559, Length=165, Percent_Identity=41.8181818181818, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28574296, Length=156, Percent_Identity=43.5897435897436, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281363477, Length=159, Percent_Identity=30.188679245283, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363475, Length=159, Percent_Identity=30.188679245283, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281363473, Length=159, Percent_Identity=30.188679245283, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 19036; Mature: 18905

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWKTASLPWGRQHRGILVPGKGKMGIMPASMFAPGRVGIISRSGTLSYEFAGILSENNV
CCCCCCCCCCCCCCCCEEECCCCCCEECCHHHCCCCCEEEEECCCCEEEEEEEEECCCCC
GQSTVVGMGADPVVLRNLTDILELFEEDEGTDAVIVVGEVGGEQEEKAAGFIKRRMTKPV
CCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHH
AAYIAGRYSPQGKRMGHAGAIVRGASGTVAGKQEALRDAGVTILDSPIHVADWAVKHKLS
HHHHHCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure 
PWKTASLPWGRQHRGILVPGKGKMGIMPASMFAPGRVGIISRSGTLSYEFAGILSENNV
CCCCCCCCCCCCCCCEEECCCCCCEECCHHHCCCCCEEEEECCCCEEEEEEEEECCCCC
GQSTVVGMGADPVVLRNLTDILELFEEDEGTDAVIVVGEVGGEQEEKAAGFIKRRMTKPV
CCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHH
AAYIAGRYSPQGKRMGHAGAIVRGASGTVAGKQEALRDAGVTILDSPIHVADWAVKHKLS
HHHHHCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]