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The map label for this gene is ubiG [H]

Identifier: 85375734

GI number: 85375734

Start: 2926035

End: 2926757

Strand: Reverse

Name: ubiG [H]

Synonym: ELI_14535

Alternate gene names: 85375734

Gene position: 2926757-2926035 (Counterclockwise)

Preceding gene: 85375735

Following gene: 85375729

Centisome position: 95.88

GC content: 65.98

Gene sequence:

>723_bases
GTGACCACTACAACCATCCGTCCCGACGAAGCCGCGCATTTCGGCGCGCTGGCGGCGGAATGGTGGGACCCGAAGGGCTC
GAGCGCGATGCTGCACCGGCTCAACCCGGTGCGGCTCGAGTTCATCCGCGAAGCGATCGACCTGCACTGGGGCGGCGATG
TCGAGGGCTTCACGCCATTGGCAGACAAGACCGCGCTCGATGTCGGCTGCGGTGCGGGGCTGCTGTGCGAGCCTTTGGCG
CGGCTGGGGGCCGATGTAACGGGCGTAGATGCAGCGGCCGAGAATATAGAAGCGGCGCAGGCCCATGCAGTCGGGATCGG
CCTCGATATCGACTACCGGCACGGCGAGCTGGCGGAATGGGGCCTTGGCCAGTTCGACTTGGTCACCTGCCTCGAAGTGA
TCGAACACGTCGCCGACAAGCGCGCGTTCCTTGCGAGCCTTGCCGAACGCCTCGCGCCGGGAGGAGTGATGATACTCTCG
ACGCCGAACAAGACCGTCAAATCGCGCTTGCTTCTCGTCGAAGCGGCCGAGGCGACCGGCATGATCCCGAGGGGCACCCA
TCACTGGGACGATTTCATCGGGCCCGAGGATCTGACCGCGCTGCTCGACGAACTGGGGCTGAGCGTCGGCGCGACCCGCG
GGATCGCCTTCTCGCCGGTCAGGGGACTGCAGCTGAGCGATGACCTGTCACTCAACTACATCCTCAGCGCGCGGCATGGG
TAG

Upstream 100 bases:

>100_bases
GATTACCCCGCCCGACTGGCTGTTCGGTGCCGATGCCAGCAGCTGGGGCGACACTTTGTTCGACAGCGTCAACGAACGCG
CCAAGACCGGAGCAATGTAA

Downstream 100 bases:

>100_bases
CCGCGCCTGATCGCGCGAGAGCAGCGCACACCATAAATCGTCATTGTTCGCCTCATCGCCCAAAGCGCAGATTGTCGGCA
GGACATCGTCGGTAAAGACC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTTTTIRPDEAAHFGALAAEWWDPKGSSAMLHRLNPVRLEFIREAIDLHWGGDVEGFTPLADKTALDVGCGAGLLCEPLA
RLGADVTGVDAAAENIEAAQAHAVGIGLDIDYRHGELAEWGLGQFDLVTCLEVIEHVADKRAFLASLAERLAPGGVMILS
TPNKTVKSRLLLVEAAEATGMIPRGTHHWDDFIGPEDLTALLDELGLSVGATRGIAFSPVRGLQLSDDLSLNYILSARHG

Sequences:

>Translated_240_residues
MTTTTIRPDEAAHFGALAAEWWDPKGSSAMLHRLNPVRLEFIREAIDLHWGGDVEGFTPLADKTALDVGCGAGLLCEPLA
RLGADVTGVDAAAENIEAAQAHAVGIGLDIDYRHGELAEWGLGQFDLVTCLEVIEHVADKRAFLASLAERLAPGGVMILS
TPNKTVKSRLLLVEAAEATGMIPRGTHHWDDFIGPEDLTALLDELGLSVGATRGIAFSPVRGLQLSDDLSLNYILSARHG
>Mature_239_residues
TTTTIRPDEAAHFGALAAEWWDPKGSSAMLHRLNPVRLEFIREAIDLHWGGDVEGFTPLADKTALDVGCGAGLLCEPLAR
LGADVTGVDAAAENIEAAQAHAVGIGLDIDYRHGELAEWGLGQFDLVTCLEVIEHVADKRAFLASLAERLAPGGVMILST
PNKTVKSRLLLVEAAEATGMIPRGTHHWDDFIGPEDLTALLDELGLSVGATRGIAFSPVRGLQLSDDLSLNYILSARHG

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=244, Percent_Identity=40.9836065573771, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1788564, Length=236, Percent_Identity=37.2881355932203, Blast_Score=153, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115533050, Length=225, Percent_Identity=35.1111111111111, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324476, Length=240, Percent_Identity=30.4166666666667, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281365311, Length=221, Percent_Identity=36.1990950226244, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24585589, Length=207, Percent_Identity=38.1642512077295, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 25591; Mature: 25460

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTIRPDEAAHFGALAAEWWDPKGSSAMLHRLNPVRLEFIREAIDLHWGGDVEGFTPL
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
ADKTALDVGCGAGLLCEPLARLGADVTGVDAAAENIEAAQAHAVGIGLDIDYRHGELAEW
CCCHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHC
GLGQFDLVTCLEVIEHVADKRAFLASLAERLAPGGVMILSTPNKTVKSRLLLVEAAEATG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHEEEEHHHCC
MIPRGTHHWDDFIGPEDLTALLDELGLSVGATRGIAFSPVRGLQLSDDLSLNYILSARHG
CCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCEECCCCCEEEEEEECCC
>Mature Secondary Structure 
TTTTIRPDEAAHFGALAAEWWDPKGSSAMLHRLNPVRLEFIREAIDLHWGGDVEGFTPL
CCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
ADKTALDVGCGAGLLCEPLARLGADVTGVDAAAENIEAAQAHAVGIGLDIDYRHGELAEW
CCCHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHC
GLGQFDLVTCLEVIEHVADKRAFLASLAERLAPGGVMILSTPNKTVKSRLLLVEAAEATG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHEEEEHHHCC
MIPRGTHHWDDFIGPEDLTALLDELGLSVGATRGIAFSPVRGLQLSDDLSLNYILSARHG
CCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA