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The map label for this gene is erg3 [H]

Identifier: 85375604

GI number: 85375604

Start: 2799360

End: 2800307

Strand: Reverse

Name: erg3 [H]

Synonym: ELI_13885

Alternate gene names: 85375604

Gene position: 2800307-2799360 (Counterclockwise)

Preceding gene: 85375605

Following gene: 85375603

Centisome position: 91.74

GC content: 61.6

Gene sequence:

>948_bases
ATGCCTGACTTTTCGCCGACTCAATACGCAGTACCGGGCTTCGTGCTGCTGGTCCTGATCGAGATGATCTGGGCCTGGCG
GCGCAATCCGGCTGCCTACGAGCCGAAGGACACGCTCGTCAGTCTTTCTTTCGGCCTCGGCAGCACCATTGCCGGCGCGC
TGTTCGGCGGCTTCGCGTTGCTCGTATTTATCGAAGCCTATGAATATCGCCTGTTCGACATGGGGCCCGAATGGTGGACC
ATCTGGTGGGCCTGGCCGCTGTGCTTCGTACTCGACGATCTGAAATATTACTGGGTGCACCGCGCCGGGCACCGCATCCG
CTGGATGTGGGCGAGCCATGTGAACCATCACTCGAGCCAGCACTACAATCTCAGCACGGCGTTGCGACAAAGCTGGACCG
GGGCCTTCACCTTCGGCCTGCTGTTCGCGCTGCCGCTGATCCTTCTCGGCTTCCACCCGGCGATGATCGCGATCTGCGCG
GGCTTCAACCTGATCTACCAGTTCTGGATCCATACCGAAGCGATCGACCGCATGCCGCGTTGGTTCGAAGCGGTGATGAA
CACCCCGAGCCACCACCGCGTCCATCATGCGACCAATCCGCGCTATCTCGACCGCAACTATGCGGGCGTATTCATCGTCT
GGGACAAGATGTTCGGCACGTTCGAACCGGAAACCGGCGAAGAGAAAATCCGCTACGGCATCGTCAAGCAATTGGGCAGC
TTCAACCTGCTGTGGGCGGTCTTCCACGAGTGGATCGGTATGGCGCAGGATATCTGGCGCGCGCCGTGGAGGCACAAGCT
CGGGTACCTGCTGCGCGAACCCGGCTGGACGCATGACGGCAGCCGCGACACATCCGACACGATCCGCGATCGCTGGCGCG
CGCGCACGGCCAACGAGCCGTCCGATACCGCCGAAAAGCCGATTGCCGGAACAGAGCAGGCTGCGTAA

Upstream 100 bases:

>100_bases
ACAGTCGATAGCGGCGAGCGGCGTTTTGGCACAATCACGCTGGCCCTCGACGACGGGGCATATTGGGAGAGCGCGATCAA
TCGGCTAAAGGCTATCAGCA

Downstream 100 bases:

>100_bases
CGCTTTCCTTCAAGAGGAGAGCATCGTGAATCAATACGACTACATCGTGATCGGCGGCGGCAGTGCAGGCAGCGCGGTGG
CCGGACGGCTGGCCGTCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPDFSPTQYAVPGFVLLVLIEMIWAWRRNPAAYEPKDTLVSLSFGLGSTIAGALFGGFALLVFIEAYEYRLFDMGPEWWT
IWWAWPLCFVLDDLKYYWVHRAGHRIRWMWASHVNHHSSQHYNLSTALRQSWTGAFTFGLLFALPLILLGFHPAMIAICA
GFNLIYQFWIHTEAIDRMPRWFEAVMNTPSHHRVHHATNPRYLDRNYAGVFIVWDKMFGTFEPETGEEKIRYGIVKQLGS
FNLLWAVFHEWIGMAQDIWRAPWRHKLGYLLREPGWTHDGSRDTSDTIRDRWRARTANEPSDTAEKPIAGTEQAA

Sequences:

>Translated_315_residues
MPDFSPTQYAVPGFVLLVLIEMIWAWRRNPAAYEPKDTLVSLSFGLGSTIAGALFGGFALLVFIEAYEYRLFDMGPEWWT
IWWAWPLCFVLDDLKYYWVHRAGHRIRWMWASHVNHHSSQHYNLSTALRQSWTGAFTFGLLFALPLILLGFHPAMIAICA
GFNLIYQFWIHTEAIDRMPRWFEAVMNTPSHHRVHHATNPRYLDRNYAGVFIVWDKMFGTFEPETGEEKIRYGIVKQLGS
FNLLWAVFHEWIGMAQDIWRAPWRHKLGYLLREPGWTHDGSRDTSDTIRDRWRARTANEPSDTAEKPIAGTEQAA
>Mature_314_residues
PDFSPTQYAVPGFVLLVLIEMIWAWRRNPAAYEPKDTLVSLSFGLGSTIAGALFGGFALLVFIEAYEYRLFDMGPEWWTI
WWAWPLCFVLDDLKYYWVHRAGHRIRWMWASHVNHHSSQHYNLSTALRQSWTGAFTFGLLFALPLILLGFHPAMIAICAG
FNLIYQFWIHTEAIDRMPRWFEAVMNTPSHHRVHHATNPRYLDRNYAGVFIVWDKMFGTFEPETGEEKIRYGIVKQLGSF
NLLWAVFHEWIGMAQDIWRAPWRHKLGYLLREPGWTHDGSRDTSDTIRDRWRARTANEPSDTAEKPIAGTEQAA

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=279, Percent_Identity=40.1433691756272, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI25144659, Length=254, Percent_Identity=34.6456692913386, Blast_Score=143, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 36763; Mature: 36632

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFSPTQYAVPGFVLLVLIEMIWAWRRNPAAYEPKDTLVSLSFGLGSTIAGALFGGFAL
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHH
LVFIEAYEYRLFDMGPEWWTIWWAWPLCFVLDDLKYYWVHRAGHRIRWMWASHVNHHSSQ
HHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCC
HYNLSTALRQSWTGAFTFGLLFALPLILLGFHPAMIAICAGFNLIYQFWIHTEAIDRMPR
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFEAVMNTPSHHRVHHATNPRYLDRNYAGVFIVWDKMFGTFEPETGEEKIRYGIVKQLGS
HHHHHHCCCCCCEEECCCCCCEECCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHCC
FNLLWAVFHEWIGMAQDIWRAPWRHKLGYLLREPGWTHDGSRDTSDTIRDRWRARTANEP
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
SDTAEKPIAGTEQAA
CCHHCCCCCCCCCCC
>Mature Secondary Structure 
PDFSPTQYAVPGFVLLVLIEMIWAWRRNPAAYEPKDTLVSLSFGLGSTIAGALFGGFAL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHH
LVFIEAYEYRLFDMGPEWWTIWWAWPLCFVLDDLKYYWVHRAGHRIRWMWASHVNHHSSQ
HHHHHHHHHHEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCC
HYNLSTALRQSWTGAFTFGLLFALPLILLGFHPAMIAICAGFNLIYQFWIHTEAIDRMPR
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFEAVMNTPSHHRVHHATNPRYLDRNYAGVFIVWDKMFGTFEPETGEEKIRYGIVKQLGS
HHHHHHCCCCCCEEECCCCCCEECCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHCC
FNLLWAVFHEWIGMAQDIWRAPWRHKLGYLLREPGWTHDGSRDTSDTIRDRWRARTANEP
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
SDTAEKPIAGTEQAA
CCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]